NURS 5357 Neurobiology Exam 1 Questions and Answers (Verified Answers)
Most Recent exam COMPLETE (2026) (Latest Update 2026) UPDATE!!
What are the three major hypotheses of psychosis and their neurotransmitter networks? -
(ANSWER)Dopamine theory - hyperactive dopamine at D2 receptors in the mesolimbic pathway
Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the cortex
Briefly explain the dopamine hypothesis of the positive and negative symptoms of schizophrenia. -
(ANSWER)The dopamine hypothesis of schizophrenia consists of:
There is too much dopamine activity in the mesolimbic dopamine pathway, which leads to positive
symptoms (such as hallucinations and delusions).
There is also too little dopamine activity in the mesocortical dopamine pathway, which leads to negative
symptoms (such as blunting of affect, poverty of speech, anhedonia, and so on).
What pathway is responsible for regulating dopamine in the hypothalamus and affects the release of
prolactin? - (ANSWER)Tuberoinfundibular pathway
Drug-induced Parkinson's is caused by a decrease of dopamine in what pathway? -
(ANSWER)Nigrostriatal pathway
Brodmann's areas are differentiated by the: - (ANSWER)Cellular architecture
All of the following are true about the hippocampus except that it: - (ANSWER)Is disrupted by frontal
lobotomy
Which of the following statements is true about the cerebellum: - (ANSWER)Has been implicated in
autism.
Cytokines are involved with all of the following except: - (ANSWER)identifying T. pallidum
, NURS 5357 Neurobiology Exam 1 Questions and Answers (Verified Answers)
Most Recent exam COMPLETE (2026) (Latest Update 2026) UPDATE!!
Which of the following is a possible explanation for schizophrenia: - (ANSWER)Excessive pruning
Possible explanations for the role of thyroid hormone in mood disorders include all of the following
except: - (ANSWER)Changes in GR's
All of the following are plausible theories on the etiology of schizophrenia except? - (ANSWER)Dopamine
hypothesis
Auditory hallucinations have been shown to activate which region on fMRI? - (ANSWER)Superior
temporal lobe
All of the following suggest white matter impairment in schizophrenia except? - (ANSWER)Significantly
reduced white matter volume
Evidence that GABA interneurons are impaired in schizophrenia - (ANSWER)Reduced GAD67
All of the following support the reduced neuropil hypothesis except? - (ANSWER)oligodendrocyte
dysfunction
Evidence that schizophrenia is a biological disorder includes all of the following except? -
(ANSWER)Gliosis in the prefrontal cortex
Neurodevelopmental causes that could explain schizophrenia include excessive amounts of all of the
following except: - (ANSWER)Myelination
The NP's discuss a patient diagnosed with schizophrenia. The PMHNP knows that which of the following
groups of symptoms is most likely to be categorized as "negative symptoms" of schizophrenia? -
(ANSWER)Blunted affect, poor rapport, lack of spontaneity
Most Recent exam COMPLETE (2026) (Latest Update 2026) UPDATE!!
What are the three major hypotheses of psychosis and their neurotransmitter networks? -
(ANSWER)Dopamine theory - hyperactive dopamine at D2 receptors in the mesolimbic pathway
Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the cortex
Briefly explain the dopamine hypothesis of the positive and negative symptoms of schizophrenia. -
(ANSWER)The dopamine hypothesis of schizophrenia consists of:
There is too much dopamine activity in the mesolimbic dopamine pathway, which leads to positive
symptoms (such as hallucinations and delusions).
There is also too little dopamine activity in the mesocortical dopamine pathway, which leads to negative
symptoms (such as blunting of affect, poverty of speech, anhedonia, and so on).
What pathway is responsible for regulating dopamine in the hypothalamus and affects the release of
prolactin? - (ANSWER)Tuberoinfundibular pathway
Drug-induced Parkinson's is caused by a decrease of dopamine in what pathway? -
(ANSWER)Nigrostriatal pathway
Brodmann's areas are differentiated by the: - (ANSWER)Cellular architecture
All of the following are true about the hippocampus except that it: - (ANSWER)Is disrupted by frontal
lobotomy
Which of the following statements is true about the cerebellum: - (ANSWER)Has been implicated in
autism.
Cytokines are involved with all of the following except: - (ANSWER)identifying T. pallidum
, NURS 5357 Neurobiology Exam 1 Questions and Answers (Verified Answers)
Most Recent exam COMPLETE (2026) (Latest Update 2026) UPDATE!!
Which of the following is a possible explanation for schizophrenia: - (ANSWER)Excessive pruning
Possible explanations for the role of thyroid hormone in mood disorders include all of the following
except: - (ANSWER)Changes in GR's
All of the following are plausible theories on the etiology of schizophrenia except? - (ANSWER)Dopamine
hypothesis
Auditory hallucinations have been shown to activate which region on fMRI? - (ANSWER)Superior
temporal lobe
All of the following suggest white matter impairment in schizophrenia except? - (ANSWER)Significantly
reduced white matter volume
Evidence that GABA interneurons are impaired in schizophrenia - (ANSWER)Reduced GAD67
All of the following support the reduced neuropil hypothesis except? - (ANSWER)oligodendrocyte
dysfunction
Evidence that schizophrenia is a biological disorder includes all of the following except? -
(ANSWER)Gliosis in the prefrontal cortex
Neurodevelopmental causes that could explain schizophrenia include excessive amounts of all of the
following except: - (ANSWER)Myelination
The NP's discuss a patient diagnosed with schizophrenia. The PMHNP knows that which of the following
groups of symptoms is most likely to be categorized as "negative symptoms" of schizophrenia? -
(ANSWER)Blunted affect, poor rapport, lack of spontaneity
