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EPIDEMIOLOGY & BIOSTATISTICS EXAM PREP | 200+ PRACTICE QUESTIONS & ANSWERS | MPH CERTIFICATION TESTBANK

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Pass your Epidemiology and Biostatistics exam with confidence. This comprehensive practice test features 200+ realistic questions with detailed rationales covering every domain — disease frequency measures (incidence rate, cumulative incidence, point prevalence, period prevalence, attack rate), mortality measures (case fatality, cause-specific mortality, proportionate mortality, YPLL), study designs (cohort, case-control, cross-sectional, RCT, ecologic, nested case-control), measures of association (relative risk, odds ratio, risk difference, attributable risk, population attributable risk fraction, NNT, NNH), bias & confounding (selection bias, recall bias, detection bias, healthy worker effect, confounding, effect modification), screening & diagnostics (sensitivity, specificity, PPV, NPV, likelihood ratios, ROC curves, lead-time bias, length bias, overdiagnosis), statistical inference (p-values, confidence intervals, Type I/II error, power, sample size), descriptive statistics (mean, median, standard deviation, IQR, box plots, histograms, scatter plots), and statistical tests (t-test, paired t-test, ANOVA, chi-square, Mann-Whitney U, Wilcoxon signed-rank, Kruskal-Wallis, Pearson correlation, linear regression, logistic regression, survival analysis). Each answer explains the why behind the formula and interpretation, not just the correct letter. Written for MPH students, epidemiology certificate candidates, biostatistics learners, and anyone preparing for graduate-level epidemiology or biostatistics exams (e.g., CPH, PHR, USMLE, COMLEX). Master the material and walk into your exam confident and prepared.

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EPIDEMIOLOGY AND BIOSTATISTICS

|ACTUAL 300Qs&As|GRADED A+

Q1. In a population of 10,000 persons, 200 new cases of a

disease occurred during a 1-year period. What is the cumulative

incidence?

a) 2 per 1,000

b) 20 per 1,000

c) 2%

d) Both b and c

Correct Answer: d) Both b and c

*Rationale: Cumulative incidence = (new cases) / (population at

risk) = 200/10,000 = 0.02 = 2% = 20 per 1,000.*

Q2. A study follows 500 healthy women for 5 years. At baseline,

50 have the disease of interest and are excluded. Over 5 years,

30 new cases occur. Total person-years of follow-up is 2,250.

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What is the incidence rate?

a) 6 per 1,000 person-years

b) 13.3 per 1,000 person-years

c) 30 per 1,000 person-years

d) 60 per 1,000 person-years

Correct Answer: b) 13.3 per 1,000 person-years

*Rationale: Incidence rate = new cases / person-time = 30 /

2,250 = 0.01333 = 13.3 per 1,000 person-years.*

Q3. Which measure of disease frequency is most appropriate

for a rapidly fatal disease with short duration?

a) Point prevalence

b) Period prevalence

c) Incidence rate

d) Cumulative incidence

Correct Answer: c) Incidence rate

Rationale: For short-duration diseases, prevalence approximates

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incidence × duration. Incidence rate (person-time) is preferred

because it accounts for varying follow-up and is less affected by

disease duration.

Q4. In a cross-sectional survey of 1,000 adults, 100 have

hypertension. What is the prevalence of hypertension?

a) 1%

b) 5%

c) 10%

d) 20%

Correct Answer: c) 10%

*Rationale: Prevalence = (existing cases) / (total population) =

100/1,000 = 0.10 = 10%.*

Q5. A cohort study follows 2,000 smokers and 3,000 non-

smokers for 10 years. At the end, there are 200 lung cancer

cases among smokers and 30 among non-smokers. The incidence

rate ratio (relative risk) is approximately:

, Page 4 of 76


a) 0.33

b) 1.5

c) 6.7

d) 10.0

Correct Answer: d) 10.0

*Rationale: Incidence smokers = 200/2,000 = 0.10 = 10%.

Incidence non-smokers = 30/3,000 = 0.01 = 1%. Risk ratio =

0..01 = 10.0.*

Q6. If the incidence of a disease is 5 per 10,000 person-years

and the average duration is 2 years, what is the approximate

prevalence?

a) 1 per 10,000

b) 5 per 10,000

c) 10 per 10,000

d) 25 per 10,000

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