MPJE ILLINOIS PHARMACY LAW EXAM – PRACTICE QUESTIONS AND CORRECT ANSWERS
(VERIFIED ANSWERS) PLUS RATIONALES 2026 Q&A | INSTANT DOWNLOAD PDF.
CORE DOMAINS
- Controlled Substances
- Pharmacy Licensure and Practice Acts
- Prescription Requirements and Recordkeeping
- Federal and State Labeling Regulations
- Pharmacist Responsibilities and Ethics
- Pharmacy Technicians and Supervision
- Compounding Standards
- Collaborative Practice Agreements
- Inventory Management and Distribution
INTRODUCTION
*The purpose of this practice examination is to evaluate candidates on their proficiency in Illinois
SECTION ONE: QUESTIONS 1–100
1. Under the Illinois Pharmacy Practice Act, what is the maximum number of pharmacy technicians a
pharmacist may supervise at one time in a retail setting if the pharmacist is also performing clinical
services?
, A. 2
B. 3
C. 4
D. 5
🟢 B. 3
🔴 RATIONALE: Illinois law typically limits the supervision ratio to three technicians per pharmacist
in a retail setting to ensure adequate oversight of technical functions.
2. A patient presents a prescription for a Schedule II controlled substance. The prescription is dated 35
days ago. What action should the pharmacist take?
A. Fill the prescription as it is valid for 6 months.
B. Call the prescriber to verify the patient still needs the medication.
C. Refuse to fill the prescription as it has expired under federal and state law.
D. Fill a partial quantity and request a new prescription for the remainder.
🟢 C. Refuse to fill the prescription as it has expired under federal and state law.
🔴 RATIONALE: While federal law does not explicitly state an expiration date for Schedule II
prescriptions, Illinois law and professional standards require that these prescriptions be filled within a
reasonable time, generally interpreted as 90 days, but pharmacy policy often mandates shorter
timeframes to prevent diversion.
3. Which of the following best describes the requirements for a pharmacist to engage in collaborative
practice in Illinois?
A. Completion of a specific certification program only.
B. A written collaborative practice agreement with a physician.
C. Five years of active pharmacy practice experience.
D. Direct supervision by a board-certified physician.
🟢 B. A written collaborative practice agreement with a physician.
, 🔴 RATIONALE: Collaborative practice in Illinois is governed by a formal written agreement between
a pharmacist and a physician, outlining the scope of clinical services the pharmacist may provide.
4. A pharmacy must report the theft or significant loss of controlled substances to the DEA using which
form?
A. DEA Form 106
B. DEA Form 222
C. DEA Form 41
D. DEA Form 224
🟢 A. DEA Form 106
🔴 RATIONALE: DEA Form 106 is the mandatory form used to document and report the theft or
significant loss of controlled substances to the DEA.
5. When compounding a sterile preparation, what is the primary standard that a pharmacy must follow?
A. USP <795>
B. USP <797>
C. USP <800>
D. USP <1163>
🟢 B. USP <797>
🔴 RATIONALE: USP <797> provides the mandatory standards for pharmaceutical compounding of
sterile preparations to ensure patient safety and product quality.
6. A pharmacist is requested to transfer a prescription for a Schedule III controlled substance to
another pharmacy. How many times can this be transferred?
A. Never
B. Once
C. Up to 5 times
D. As many times as there are refills remaining
, 🟢 B. Once
🔴 RATIONALE: Federal regulations permit the transfer of Schedule III-V controlled substance
prescriptions between pharmacies on a one-time basis only, unless the pharmacies share a real-
time, online electronic database.
7. Which agency is primarily responsible for the enforcement of the Illinois Controlled Substances Act?
A. Illinois Department of Financial and Professional Regulation (IDFPR)
B. Drug Enforcement Administration (DEA)
C. Department of Human Services
D. Food and Drug Administration (FDA)
🟢 A. Illinois Department of Financial and Professional Regulation (IDFPR)
🔴 RATIONALE: The IDFPR, through the Division of Professional Regulation, is the state agency
charged with licensing and enforcing pharmacy law and the Controlled Substances Act within Illinois.
8. A patient requests a refill of a non-controlled medication. How long must the pharmacy maintain the
record of this refill?
A. 1 year
B. 2 years
C. 5 years
D. 7 years
🟢 C. 5 years
🔴 RATIONALE: Illinois law requires that all prescription records, including refills, be maintained for
a period of at least five years.
9. Which of the following is required on the label of a dispensed prescription in Illinois?
A. The prescriber's DEA number
B. The pharmacy's DEA number
C. The serial number of the prescription
(VERIFIED ANSWERS) PLUS RATIONALES 2026 Q&A | INSTANT DOWNLOAD PDF.
CORE DOMAINS
- Controlled Substances
- Pharmacy Licensure and Practice Acts
- Prescription Requirements and Recordkeeping
- Federal and State Labeling Regulations
- Pharmacist Responsibilities and Ethics
- Pharmacy Technicians and Supervision
- Compounding Standards
- Collaborative Practice Agreements
- Inventory Management and Distribution
INTRODUCTION
*The purpose of this practice examination is to evaluate candidates on their proficiency in Illinois
SECTION ONE: QUESTIONS 1–100
1. Under the Illinois Pharmacy Practice Act, what is the maximum number of pharmacy technicians a
pharmacist may supervise at one time in a retail setting if the pharmacist is also performing clinical
services?
, A. 2
B. 3
C. 4
D. 5
🟢 B. 3
🔴 RATIONALE: Illinois law typically limits the supervision ratio to three technicians per pharmacist
in a retail setting to ensure adequate oversight of technical functions.
2. A patient presents a prescription for a Schedule II controlled substance. The prescription is dated 35
days ago. What action should the pharmacist take?
A. Fill the prescription as it is valid for 6 months.
B. Call the prescriber to verify the patient still needs the medication.
C. Refuse to fill the prescription as it has expired under federal and state law.
D. Fill a partial quantity and request a new prescription for the remainder.
🟢 C. Refuse to fill the prescription as it has expired under federal and state law.
🔴 RATIONALE: While federal law does not explicitly state an expiration date for Schedule II
prescriptions, Illinois law and professional standards require that these prescriptions be filled within a
reasonable time, generally interpreted as 90 days, but pharmacy policy often mandates shorter
timeframes to prevent diversion.
3. Which of the following best describes the requirements for a pharmacist to engage in collaborative
practice in Illinois?
A. Completion of a specific certification program only.
B. A written collaborative practice agreement with a physician.
C. Five years of active pharmacy practice experience.
D. Direct supervision by a board-certified physician.
🟢 B. A written collaborative practice agreement with a physician.
, 🔴 RATIONALE: Collaborative practice in Illinois is governed by a formal written agreement between
a pharmacist and a physician, outlining the scope of clinical services the pharmacist may provide.
4. A pharmacy must report the theft or significant loss of controlled substances to the DEA using which
form?
A. DEA Form 106
B. DEA Form 222
C. DEA Form 41
D. DEA Form 224
🟢 A. DEA Form 106
🔴 RATIONALE: DEA Form 106 is the mandatory form used to document and report the theft or
significant loss of controlled substances to the DEA.
5. When compounding a sterile preparation, what is the primary standard that a pharmacy must follow?
A. USP <795>
B. USP <797>
C. USP <800>
D. USP <1163>
🟢 B. USP <797>
🔴 RATIONALE: USP <797> provides the mandatory standards for pharmaceutical compounding of
sterile preparations to ensure patient safety and product quality.
6. A pharmacist is requested to transfer a prescription for a Schedule III controlled substance to
another pharmacy. How many times can this be transferred?
A. Never
B. Once
C. Up to 5 times
D. As many times as there are refills remaining
, 🟢 B. Once
🔴 RATIONALE: Federal regulations permit the transfer of Schedule III-V controlled substance
prescriptions between pharmacies on a one-time basis only, unless the pharmacies share a real-
time, online electronic database.
7. Which agency is primarily responsible for the enforcement of the Illinois Controlled Substances Act?
A. Illinois Department of Financial and Professional Regulation (IDFPR)
B. Drug Enforcement Administration (DEA)
C. Department of Human Services
D. Food and Drug Administration (FDA)
🟢 A. Illinois Department of Financial and Professional Regulation (IDFPR)
🔴 RATIONALE: The IDFPR, through the Division of Professional Regulation, is the state agency
charged with licensing and enforcing pharmacy law and the Controlled Substances Act within Illinois.
8. A patient requests a refill of a non-controlled medication. How long must the pharmacy maintain the
record of this refill?
A. 1 year
B. 2 years
C. 5 years
D. 7 years
🟢 C. 5 years
🔴 RATIONALE: Illinois law requires that all prescription records, including refills, be maintained for
a period of at least five years.
9. Which of the following is required on the label of a dispensed prescription in Illinois?
A. The prescriber's DEA number
B. The pharmacy's DEA number
C. The serial number of the prescription
