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1. Figure 11.4 Nu- Chapter 11 Concept Checks
cleotides and their Figure 11.4 Cytosine is found in both DNA and RNA.
components. For
simplicity, the car-
bon atoms in the
ring structures are
shown only for gua-
nine and cytosine
in part (a).
Concept Check:
Which pyrimi-
dine(s) is (are)
found in both DNA
and RNA?
2. Figure 11.5 Con- Chapter 11 Concept Checks
ventional number- Figure 11.5 The phosphate is attached to the 52 carbon
ing in a DNA nu- in a DNA nucleotide.
cleotide. The car-
bons in the sug-
ar are given a
prime designation,
whereas those in
the base are not.
Concept Check:
What is the num-
bering designation
of the carbon atom
to which the phos-
phate is attached?
3. Figure 11.11 The Chapter 11 Concept Checks
Meselson and Stahl Figure 11.11 The expected fractions would be 1/8
experiment show- half-heavy and 7/8 light
ing that DNA repli-
cation is semicon-
servative. (5): -
, Biology Ch 11 Fifth Edition Brooker BRCC 1033
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Meselson, M., and
Stahl, F. 1958.
The replication of
DNA in Escherichia
coli. PNAS 44(7):
671-682, Fig. 4a
Concept Check:
If this experiment
was conducted for
four rounds of DNA
replication (that is,
four generations),
what would be
the expected frac-
tions of light DNA
and half-heavy
DNA according to
the semiconserva-
tive model?
4. Figure 11.15 En- Chapter 11 Concept Checks
zymatic synthesis Figure 11.15 The oxygen in a new phosphoester bond
of DNA. (a) In- comes from the sugar.
coming deoxynu-
cleoside triphos-
phates first hy-
drogen-bond to
the template
strand according
to the AT/GC
rule. DNA poly-
merase recognizes
these deoxynu-
cleoside triphos-
phates and attach-
es a deoxynucle-
oside monophos-
phate to the 3-
, Biology Ch 11 Fifth Edition Brooker BRCC 1033
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„end of a grow-
ing strand. (b) DNA
polymerase breaks
the bond between
the first and sec-
ond phosphate in
a deoxynucleoside
triphosphate, caus-
ing the release
of pyrophosphate.
This provides the
energy to form a
covalent bond be-
tween the result-
ing deoxynucleo-
side monophos-
phate and the pre-
vious nucleotide in
the growing strand.
The pyrophosphate
is broken down to
two phosphates.
Concept Check:
Does the oxygen
in a new phospho-
ester bond come
from the sugar
or from the phos-
phate?
5. Figure 11.17 Syn- Chapter 11 Concept Checks
thesis of new DNA Figure 11.17 The lagging strand is made discontinu-
strands. The sepa- ously in the direction opposite to the movement of the
ration of DNA at the replication fork
origin of replication
produces two repli-
cation forks that
move in oppo-