ADME EXAM QUESTIONS AND
ANSWERS
pharmacodynamics - Correct Answers -what a drug does to the body
pharmacokinetics - Correct Answers -what the body does to a drug
passive diffusion - Correct Answers -movement of drugs from area of higher
concentration to lower concentration
hydrophilic - Correct Answers -capable of associating with or absorbing water
why is drug bound the plasma proteins essentially inactive? - Correct Answers -when
drug is bound to plasma proteins, it is not free to move through biological membranes to
the site of action.
if the rate and extent of absorption of a drug from two different formulations is
statistically the same, how would the blood concentration-time profiles appear? -
Correct Answers -about the same
human variability - Correct Answers -differences in age, weight, genetics, and gender
are among the variables that influence the differences in disposition and response to
medications. it can alter blood concentration-time profiles and affect drug efficacy.
hydrophobic - Correct Answers -water repelling; cannot associate with water
active transport - Correct Answers -movement of drugs from area of lower concentration
to higher; cellular energy required
paradoxical effect - Correct Answers -a drug effect opposite of what would be expected
homeostasis - Correct Answers -state of equilibrium of the body
blocker - Correct Answers -another term for antagonist drug. antagonist drugs block the
action of neurotransmitters
mimetic - Correct Answers -another term for agonist drug, because agonists mimic or
imitate the action of the neurotransmitter
ANSWERS
pharmacodynamics - Correct Answers -what a drug does to the body
pharmacokinetics - Correct Answers -what the body does to a drug
passive diffusion - Correct Answers -movement of drugs from area of higher
concentration to lower concentration
hydrophilic - Correct Answers -capable of associating with or absorbing water
why is drug bound the plasma proteins essentially inactive? - Correct Answers -when
drug is bound to plasma proteins, it is not free to move through biological membranes to
the site of action.
if the rate and extent of absorption of a drug from two different formulations is
statistically the same, how would the blood concentration-time profiles appear? -
Correct Answers -about the same
human variability - Correct Answers -differences in age, weight, genetics, and gender
are among the variables that influence the differences in disposition and response to
medications. it can alter blood concentration-time profiles and affect drug efficacy.
hydrophobic - Correct Answers -water repelling; cannot associate with water
active transport - Correct Answers -movement of drugs from area of lower concentration
to higher; cellular energy required
paradoxical effect - Correct Answers -a drug effect opposite of what would be expected
homeostasis - Correct Answers -state of equilibrium of the body
blocker - Correct Answers -another term for antagonist drug. antagonist drugs block the
action of neurotransmitters
mimetic - Correct Answers -another term for agonist drug, because agonists mimic or
imitate the action of the neurotransmitter
