5/24/26, 6:35 PM BOD: Renal: Pathophysiology of Acid-base Disorders — Test
Test
BOD: Renal: Pathophysiology of Acid-base Disorders
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,5/24/26, 6:35 PM BOD: Renal: Pathophysiology of Acid-base Disorders — Test
QUESTION
What is a "normal" anion gap?
around 10 mEq/L. (anything below 12)
QUESTION
The appropriate respiratory compensation in metabolic
acidosis can be calculated using what formula?
The Winter Formula:
Expected PCO2 = 1.5[HCO3-] + 8 +/- 2
For example, if bicarb was 16 mEq/L, then [(1.5 x 16) + 8]
= approx 32. (This would indicate that the person was
breathing at an increased rate, blowing off CO2)
QUESTION
What is the primary cause of reduced H+ excretion in
renal failure? (What can worsen this situation?)
https://www.cram.com/flashcards/bod-renal-pathophysiology-of-acid-base-disorders-913395/test 2/2
, 5/24/26, 6:35 PM BOD: Renal: Pathophysiology of Acid-base Disorders — Test
Inadequate amt of urinary ammonia. (Hyperkalemia can
worsen this acidosis).
QUESTION
What is meant by "hyperchloremic acidosis"?
When the fall in serum bicarbonate is matched by a rise
in chloride levels. Thus, the chloride levels rise, but the
anion gap does not (think: Cl- + HCO3-)
QUESTION
Explain Type 1 Renal Tubular Acidosis. Explain how it
affects H+, Na+, and K+.
This is a distal RTA. H+ secretion into the collecting
tubules is impaired. H+ is not sec, so get metabolic
acidosis. Na+ can still be exchanged for K+, however, so
often see marked hypokalemia with a urine with a pH of
5.5 to 6.0 (Higher than you'd expect for an acidotic
individual. Higher because the patient can’ t acidify the
urine).
https://www.cram.com/flashcards/bod-renal-pathophysiology-of-acid-base-disorders-913395/test 3/3
Test
BOD: Renal: Pathophysiology of Acid-base Disorders
Incorrect 0 Skipped 0 Correct 50
1/1
,5/24/26, 6:35 PM BOD: Renal: Pathophysiology of Acid-base Disorders — Test
QUESTION
What is a "normal" anion gap?
around 10 mEq/L. (anything below 12)
QUESTION
The appropriate respiratory compensation in metabolic
acidosis can be calculated using what formula?
The Winter Formula:
Expected PCO2 = 1.5[HCO3-] + 8 +/- 2
For example, if bicarb was 16 mEq/L, then [(1.5 x 16) + 8]
= approx 32. (This would indicate that the person was
breathing at an increased rate, blowing off CO2)
QUESTION
What is the primary cause of reduced H+ excretion in
renal failure? (What can worsen this situation?)
https://www.cram.com/flashcards/bod-renal-pathophysiology-of-acid-base-disorders-913395/test 2/2
, 5/24/26, 6:35 PM BOD: Renal: Pathophysiology of Acid-base Disorders — Test
Inadequate amt of urinary ammonia. (Hyperkalemia can
worsen this acidosis).
QUESTION
What is meant by "hyperchloremic acidosis"?
When the fall in serum bicarbonate is matched by a rise
in chloride levels. Thus, the chloride levels rise, but the
anion gap does not (think: Cl- + HCO3-)
QUESTION
Explain Type 1 Renal Tubular Acidosis. Explain how it
affects H+, Na+, and K+.
This is a distal RTA. H+ secretion into the collecting
tubules is impaired. H+ is not sec, so get metabolic
acidosis. Na+ can still be exchanged for K+, however, so
often see marked hypokalemia with a urine with a pH of
5.5 to 6.0 (Higher than you'd expect for an acidotic
individual. Higher because the patient can’ t acidify the
urine).
https://www.cram.com/flashcards/bod-renal-pathophysiology-of-acid-base-disorders-913395/test 3/3
