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Western Governors University D027 Advanced Pharmacology Objective Assessment Study Guide and Practice Resource

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This study resource is designed to support learning in advanced pharmacology by helping students strengthen understanding of drug therapy principles, medication safety, and clinical application of pharmacological knowledge. It emphasizes critical thinking, clinical judgment, and evidence-based decision-making in medication management. The material covers key topics such as pharmacokinetics and pharmacodynamics, drug classifications, mechanisms of action, adverse drug reactions, contraindications, dosage calculations, patient education, autonomic nervous system drugs, cardiovascular medications, antibiotics, endocrine therapies, pain management, psychiatric medications, and safe medication administration practices. It also focuses on applying pharmacology concepts to clinical nursing care and patient safety outcomes. This resource is suitable for students preparing for Western Governors University D027 coursework, objective assessments, competency evaluations, nursing examinations, and pharmacology review studies.

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Institution
Pharmacology
Course
Pharmacology

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WGU D027 OA EXAM 2024-2025 ACTUAL
EXAM TEST BANK 100 QUESTIONS AND
CORRECT DETAILED ANSWERS WITH
RATIONALES |A GRADE
What is the gold standard for the suspected diagnosis of Celiac Disease? – Answer
endoscopy with small intestine biopsy

A 44-year-old woman has recently been diagnosed with advanced metastatic non-small-cell lung
cancer. Genetic testing is ordered to determine if the patient's tumor has any genomic alterations
and to guide treatment decisions. A few weeks later, the patient's test results come back positive
for a genetic mutation. The APN starts osimertinib (Tagrisso). Based on this information, what
type of genetic mutation does this patient have? – answer EGFR mutation

A 20-year-old male meets with an advanced professional nurse (APN) to discuss symptoms that
have been slowly progressing over the past several years. He is mainly concerned because he has
been falling frequently. Since childhood, his gait has consisted of walking on his toes. During
middle school, he was able to participate in sports but was unable to participate in high school
sports due to difficulty with running and jumping. Lately, he has noticed it takes longer and is
more difficult to change positions from sitting to standing than it used to in the past. He has also
been waking up with muscle and joint stiffness. The APRN notes that his family history is not
significant for any chronic or genetic diseases. Which condition is likely to be the cause of these
symptoms? – answer Becker muscular dystrophy
--Becker muscular dystrophy (often called Becker MD or BMD) is a form of muscular dystrophy,
a genetic disorder that gradually makes the body's muscles weaker and smaller. It causes less
severe problems than the most common type, Duchenne muscular dystrophy.

Which statement should the provider give the patient regarding the pathophysiology of SLE and
its relation to thrombocytopenia? – answer SLE disrupts immune homeostasis and promotes
development of self-reactive antibodies.

A female patient presents to an office to establish care. Her previous primary care provider told
her to follow up regarding an elevated ferritin level. She has no previous medical history and is
currently asymptomatic. She is concerned about the elevated ferritin and would like to know if
she should be worried. What should the provider do next for this patient? – answer Order a
liver function test

A 75-year-old female presents to the emergency department with an irregular heart rate of
130.What can be ascertained about this patient's findings given the limited

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,information? – answer She is diagnosed with atrial fibrillation and needs her heart rate
controlled with metoprolol (Lopressor).

Which condition from this patient's medical history is contributing to the loss of
contractility? – answer Acute myocardial infarction

Which condition is this patient suffering from? – answer Diabetic ketoacidosis

A 45-year-old female fears that she is having a stroke and takes herself to an
emergency room. After several diagnostic and laboratory tests, the patient is diagnosed with
Cushing disease. Which lab abnormality would be present in this patient? – answer Increased
cortisol

SOB when lying down, and moving around --Based on the patient's presentation, which disease
process is the patient likely exhibiting? – answer Asthma

A two-year-old child presents with a clear runny nose and cough which has lasted 3 days. The
child's mother reports the cough sounds like a barking noise. The child is sleeping in the
mother's arms and appears to have stridor. The child's mother also reports an axillary
temperature of 101°F last night. Which management technique is appropriate for this child's
symptoms? – answer Oral steroids and breathing treatments

Delerium, urinary incontinence, fever-- Which lab and diagnostic tests should be ordered as part
of the patient's assessment? – answer Complete blood count, complete metabolic profile, and
urinalysis

An 18-year-old male is involved in a motorcycle crash while not wearing a helmet. He is brought
into an emergency room and is immediately taken for a CT scan. The provider tells the patient's
parents he has bleeding between the dura mater and the skull. What is this patient's condition
called? – answer Epidural hematoma

-- What is the appropriate diagnosis for this patient? – answer Crohn's disease

Which diagnostic test is appropriate to order for this patient? – answer Ultrasound

A 45-year-old male is being seen in the clinic for a yearly check-up and lab work. His history
includes hypertension and hyperlipidemia for which he currently takes Norvasc 5 mg daily and
Lipitor 20 mg nightly. Patient has a family history of diabetes,
hypertension, heart disease, and hyperlipidemia. After obtaining lab work, the provider notices
the patient's hgbA1c is elevated at 7.5. The patient is already on a DASH diet and watching the
amount of sweets and carbohydrates he eats daily. The patient is not overweight and participates
in moderate physical activity at least 4-5 days a week. He was started on Metformin three months
ago, and his hemoglobin A1c is now 6.9. The nurse expects to see a class of medication
prescribed which is proven to reduce the risk of cardiovascular events. Considering the treatment
guidelines from the American



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, College of Cardiology, which medication should be recommended for this patien – answer
Invokana 100 mg daily
--Invokana is a medication used to treat type 2 diabetes. It is a third-line medication to
metformin. It is used together with exercise and diet. It is not recommended in type 1 diabetes.
It is taken by mouth.

A 78-year-old female presents to the clinic for a checkup and refills on her medications.
She is currently taking lisinopril (Zestril), metformin (Glucophage), and levothyroxine
(Synthroid). The patient has a history of hypertension, type 2 diabetes, hypothyroidism, GERD,
and gastric ulcers. The patient is concerned about heart disease and wants to start taking a low-
dose aspirin. Which aspirin regimen recommendation should the advanced professional nurse
(APN) give to the patient? – answer Low-dose enteric coated aspirin 81 mg daily

A 28-year-old married female presents to primary care accompanied by her husband with
complaints of weight gain, fatigue, muscle aches, bloating, constipation, and difficulty
concentrating. The patient explains that she has been experiencing these symptoms with
increasing frequency over the last two months and reports feeling upset that she has gained 10
pounds over the past month despite no significant changes in dietary intake or activity level. The
patient holds a bachelor's degree and is employed full time as an accountant. The patient reports
feeling frustrated with her poor
concentration and identifies recent work errors to be due to this symptom. The patient explains
that she and her spouse plan to start trying to conceive soon, and she is worried that she may have
trouble becoming pregnant. The patient reports using over-the-counter laxative products over the
last week to combat constipation. The patient repo – answer 5.31 mIU/L

A 74- year-old male with Cushing syndrome presents to the emergency department (ED) with
pain in his left leg, and is diagnosed with a deep vein thrombosis (DVT).What is this patient's
symptoms related to? – answer Elevated Von Willebrand factor

A 42-year-old asthmatic who has been using beta-adrenergic agonists for several years began to
experience premature atrial contractions (PACs). To treat the PACs,
metoprolol (Toprol XL) therapy was started.What is a likely consequence of this patient taking
metoprolol (Toprol XL)? – answer Metoprolol (Toprol XL) worsened asthma symptoms, but
improved the PACs.
-- Beta blockers are widely used in the management of cardiac conditions and thyrotoxicosis,
and to reduce perioperative complications. Asthma and chronic obstructive pulmonary disease
(COPD) have been classic contraindications to the use of beta blockers because of their potential
for causing bronchospasm.

Which inhaler prescription would support long-acting treatment for twice-daily use in
controlled asthma management? – answer Fluticasone propionate/salmeterol (Advair Diskus)
--Fluticasone and salmeterol is a combination of two medicines that are used to help control
the symptoms of asthma and improve breathing.

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Institution
Pharmacology
Course
Pharmacology

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