Test Bank for Abrams’ Clinical Drug Therapy Rationales for Nursing Practice 13th Edition by Frandsen & Pennington ISBN 9781975222321 Complete All Chapters

TestBank ForAbrams’ClinicalDrugTherapy R
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ationalesforNursingPractice13thEdition
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(Vers ion 2026/2027) Geralyn Frandsen
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Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the
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expected effect for this prescription?
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A. Curative effect on symptoms e e e



B. Systemic effect on symptoms e e e



C. Local effect on symptoms e e e



D. Parenteral effect on symptoms e e e




ANS: B e e



Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
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bloodstream to their sites of action in various body tissues, and eventually eliminated from
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the body. Curative agents are given to cure a disease process. In this case, paroxeti ne
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hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff ects,
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such as sunscreen and local anesthetics, act mainly at the site of application. Paroxet ine
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hydrochloride is not administered parenterally. Parenteral agents are administered sub
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cutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 e e



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
e Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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eKEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understande e NOT: Multiple Choice e e e e e




2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
e mRicA
alDlyEm
SoBdOifOieSd.TW
.hCaOt Mi s another name for this type o
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f medication?
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A. Synthetic drug e
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B. Semisynthetic drug
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C. Biotechnology drug
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D. Prototype drug e
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ANS: B
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Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their chemic al
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characteristics, more consistent in their effects, and less likely to produce allergic react ions.
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Biotechnology drugs involve manipulating DNA and RNA and recombining genes i nto
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hybrid molecules that can be inserted into living organisms. Prototype drugs are the f irst drug
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of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 e e e



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
e Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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eKEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understande e NOT: Multiple Choice e e e e e




3. Which classification applies to morphine?
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A. Central nervous system depressant e e e



B. Central nervous system stimulant e e e




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C. Anti-inflammatory
D. Antihypertensive
ANS: A e e



Rationale: Drugs are classified according to their effects on particular body systems, their
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therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
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rvous system depressant and will produce this effect in the client. A central nervous syste m
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stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
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antihypertensive agent reduces blood pressure.
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PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
e Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember e e NOT: Multiple Choice e e e e e




4. A client is administered amoxicillin. The generic name of this medication belongs to whi ch
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drug group?
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A. Selective serotonin reuptake inhibitors e e e



B. Diuretics
C. Penicillins
D. ACE inhibitors e




ANS: C e e



Rationale: The generic namGeRoAfDteE
n SinBdO
icO
atS
esTt.hC
eOdrug group (e.g., drugs with generic nam es
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ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medicatio
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ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur
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etics are medications that increase urine output; diuretic is a broad classification, not a ge neric
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name. ACE inhibitor is the broad classification for the angiotensin receptor blockers, not the
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generic name.
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PTS: 1 REF: p. 3, Drug Names OBJ: 2
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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eKEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understande e NOT: Multiple Choice e e e e e




5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service e e



B. Federal Trade Commission e e



C. Occupational Safety and Health Administration e e e e



D. Food and e




Drug Administration ANS: D
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Rationale: The Food and Drug Administration approves drugs for over-the-
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counter availability, including the transfer of drugs from prescription to OTC status, and may
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require clinical trials to determine the safety and effectiveness of OTC use. The Pu blic
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Health Service is regulated by the state to maintain the health of individual citizens of
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the state. The Federal Trade Commission regulates imports and exports throughout the
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nation. The Occupational Safety and Health Administration regulates safety within the wo
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rkplace.
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PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
e e Chapter: 1: The Foundation of Pharmacology: Quality and Safety e e e e e e e e



KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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6. In the U.S., the administration of anabolic steroids is regulated by which law?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Comprehensive Drug Abuse Prevention and Control Act
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C. The Harrison Narcotic Act e e e



D. The Sherley Amendment e e




ANS: B e e



Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma
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nufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and anaboli c
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steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powe
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rs and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Ac t
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restricted the importation, manufacture, sale, and use of opium, cocaine, marijuana, and other
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drugs that the act defiGneRd Aa Ds E
naSrcBoO
tiO
csS
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erley Amendment of 1912 prohibited
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fraudulent claims of drug effectiveness.
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PTS: 1 REF:
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p. 4, Prescription and Nonprescription Drugs OBJ: 3
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
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7. A nurse is responsible for maintaining an accurate count and record of the controlled
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substances on the nursing division. This nursing action is regulated by which U.S. law or
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agency?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Public Health Service e e e



C. The Drug Enforcement Administration
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D. The Sherley Amendment e e




ANS: C
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