Test Bank for Abrams’ Clinical Drug Therapy Rationales for Nursing Practice 13th Edition by Frandsen & Pennington ISBN 9781975222321 Complete All Chapters

Test Bank For Abrams’ Clinical Drug Therapy R
g b6 g g g g g




ationales for Nursing Practice 13th Edition (Vers
g g g g g g g




ion 2026/2027) Geralyn Frandsen
g g g g

, GRADESBOOST.COM

Chapter 1, The Foundation of Pharmacology: Quality and Safety
g g g g g g g g




1. A woman diagnosed with obsessive–
g g g g



compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the
g g g g g g g g g g



expected effect for this prescription?
g g g g g



A. Curative effect on symptoms g g g



B. Systemic effect on symptoms g g g



C. Local effect on symptoms g g g



D. Parenteral effect on symptoms g g g




ANS: B g g



Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
g g g g g g g g g g g g g



bloodstream to their sites of action in various body tissues, and eventually eliminated from
g g g g g g g g g g g g g g



the body. Curative agents are given to cure a disease process. In this case, paroxeti ne
g g g g g g g g g g g g g g g g



hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff ects,
g g g g g g g g g g g g g g g



such as sunscreen and local anesthetics, act mainly at the site of application. Paroxet ine
g g g g g g g g g g g g g g g



hydrochloride is not administered parenterally. Parenteral agents are administered sub
g g g g g g g g g g



cutaneously, intramuscularly, or intravenously.
g g g g




PTS: 1 REF: p. 3, Introduction OBJ: 1 g g



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
g g g g g g g g



es TOP:
g Chapter: 1: The Foundation of Pharmacology: Quality and Safety
g g g g g g g g g



gKEY: Integrated Process: Nursing Process
g g g g



BLM: Cognitive Level: Understandg g NOT: Multiple Choice g g g g g




2. A client has been prescribed an antibiotic. This medication is a naturally occurring
g g g g g g g g g g g g
GRADESBOOST.COM
g




substance that has been cheG
g mRicA
alDlyEm
SoBdOifOieSd.TW
.hCaOt Mi s another name for this type o
g g g g b6 g g g g g g g
g




f medication?
g




g
g




A. Synthetic drug g
g




B. Semisynthetic drug
g




g
g




C. Biotechnology drug
g




g
g




D. Prototype drug g
g
g




ANS: B
g




g g
g




Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
g




g g g g g g g g g



that have been chemically modified. Synthetic drugs are more standardized in their chemic al
g g g g g g g g g g g g g g



characteristics, more consistent in their effects, and less likely to produce allergic react ions.
g g g g g g g g g g g g g g



Biotechnology drugs involve manipulating DNA and RNA and recombining genes i nto
g g g g g g g g g g g g



hybrid molecules that can be inserted into living organisms. Prototype drugs are the f irst
g g g g g g g g g g g g g g g



drug of a particular group to be developed.
g g g g g g g g




PTS: 1 REF: p. 3, Drug Sources OBJ: 1 g g g



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
g g g g g g g g



es TOP:
g Chapter: 1: The Foundation of Pharmacology: Quality and Safety
g g g g g g g g g



gKEY: Integrated Process: Nursing Process
g g g g



BLM: Cognitive Level: Understandg g NOT: Multiple Choice g g g g g




3. Which classification applies to morphine?
g g g g



A. Central nervous system depressant g g g



B. Central nervous system stimulant g g g




GRADESBOOST.COM#1TESTBANKSWEBSITE g g g g

, GRADESBOOST.COM

C. Anti-inflammatory
D. Antihypertensive
ANS: A g g



Rationale: Drugs are classified according to their effects on particular body systems, their
g g g g g g g g g g g g



therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
g g g g g g g g g g g g g



rvous system depressant and will produce this effect in the client. A central nervous syste m
g g g g g g g g g g g g g g g g



stimulant increases attention and raises mood. An anti-
g g g g g g g g



inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An g g g g g g g g g g g g



antihypertensive agent reduces blood pressure.
g g g g g




PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1 g g g g g g



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
g g g g g g g g



es TOP:
g Chapter: 1: The Foundation of Pharmacology: Quality and Safety
g g g g g g g g g



KEY: Integrated Process: Nursing Process
g g g g g



BLM: Cognitive Level: Remember NOT: Multiple Choice
g g g g g g g




4. A client is administered amoxicillin. The generic name of this medication belongs to whi ch
g g g g g g g g g g g g g g



drug group?
g g



A. Selective serotonin reuptake inhibitors g g g



B. Diuretics
C. Penicillins
D. ACE inhibitors g




ANS: C g g



Rationale: The generic namGeRoAfD
teE
n SinBdO
icO
atS
esTt.hC
eOdrug group (e.g., drugs with generic nam es
g g g b6 b6 b6 b6 g g g g g g g
GRADESBOOST.COM




ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medicatio
g




g g g g g g g g g g g
g




ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur
g




g g g g g g g g g g g g g g
g




etics are medications that increase urine output; diuretic is a broad classification, not a ge
g g g g g g g g g g g g g g g
g




neric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
g




g g g g g g g g g g g g g
g




not the generic name.
g




g g g g
g
g




PTS: 1 REF: p. 3, Drug Names OBJ: 2
g




g g g
g




NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
g




g g g g g g g g



es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
g




g g g g g g g g g g



gKEY: Integrated Process: Nursing Process g g g g



BLM: Cognitive Level: Understand NOT: Multiple Choice
g g g g g g g




5. The administration of diphenhydramine is regulated by which U.S. government agency?
g g g g g g g g g g



A. Public Health Service g g



B. Federal Trade Commission g g



C. Occupational Safety and Health Administration g g g g



D. Food and g




Drug Administration ANS: D
g b6 g




GRADESBOOST.COM#1TESTBANKSWEBSITE g g g g

, GRADESBOOST.COM

Rationale: The Food and Drug Administration approves drugs for over-the-
g g g g g g g g g



counter availability, including the transfer of drugs from prescription to OTC status, and may
g g g g g g g g g g g g g



require clinical trials to determine the safety and effectiveness of OTC use. The Pu blic
g g g g g g g g g g g g g g g



Health Service is regulated by the state to maintain the health of individual citizens of
g g g g g g g g g g g g g g g



the state. The Federal Trade Commission regulates imports and exports throughout the
g g g g g g g g g g g g



nation. The Occupational Safety and Health Administration regulates safety within the wo
g g g g g g g g g g g g



rkplace.
g




PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
g g g g g g g



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
g g g g g g g g



es TOP:
g g Chapter: 1: The Foundation of Pharmacology: Quality and Safety g g g g g g g g



KEY: Integrated Process: Nursing Process
g g g g g



BLM: Cognitive Level: Understand
g g NOT: Multiple Choice g g g g g




6. In the U.S., the administration of anabolic steroids is regulated by which law?
g g g g g g g g g g g g



A. The Food, Drug, and Cosmetic Act of 1938
g g g g g g g



B. The Comprehensive Drug Abuse Prevention and Control Act
g g g g g g g



C. The Harrison Narcotic Act g g g



D. The Sherley Amendment g g




ANS: B g g



Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma
g g g g g g g g g g g



nufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and anaboli
g g g g g g g g g g



gc steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
g g g g g g g g g g g g g



powe rs and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic
g g g g g g g g g g g g g g



Ac t restricted the importation, manufacture, sale, and use of opium, cocaine, marijuana,
GRADESBOOST.COM




g g g g g g g g g g g g g
g




and other drugs that the act defiGn eRd Aa Ds E
naSrcBoO
tiO
csS
.TTh.eCSOhM
erley Amendment of 1912
g




g g g g g g g g g g g g g b6 g g g
g




prohibited fraudulent claims of drug effectiveness.
g




g g g g g g
g
g




PTS: 1 REF:
g
g




p. 4, Prescription and Nonprescription Drugs OBJ: 3
g g g g g g g
g




NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
g




g g g g g g g g
g




es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
g




g g g g g g g g g g
g




KEY: Integrated Process: Nursing Process
g g g g g
g




BLM: Cognitive Level: Remember
g g NOT: Multiple Choice g g g g g




7. A nurse is responsible for maintaining an accurate count and record of the controlled
g g g g g g g g g g g g g



substances on the nursing division. This nursing action is regulated by which U.S. law or
g g g g g g g g g g g g g g g



agency?
g



A. The Food, Drug, and Cosmetic Act of 1938
g g g g g g g



B. The Public Health Service g g g



C. The Drug Enforcement Administration
g g g



D. The Sherley Amendment g g




ANS: C
g g





GRADESBOOST.COM#1TESTBANKSWEBSITE g g g g