APHA NAPLEX EXAM SCRIPT 2026
QUESTIONS WITH ANSWERS GRADED A+
●● Calculating a dose of new dosage form. Answer: dose of new dosage
form =
amount absorbed from current dosage form/F of new dosage form
●● Vd. Answer: dose/cp
(amount of drug in body/conc. of drug in plasma)
●● Cl. Answer: Rate of elim (ke) / Conc
or
F X dose / AUC
●● Elimination Rate constant. Answer: Ke = cl/vd
●● LD. Answer: desired concentration x Vd / F
, ●● t1/2. Answer: 0.693/ke
●● IBW for females. Answer: 45.5kg + (2.3kg)(# of inches over 5 feet)
●● IBW for men. Answer: 50kg + (2.3kg)(# inches over 5 feet)
●● ABW. Answer: IBW + 0.4(TBW-IBW)
●● dehydration. Answer: BUN:Scr > 20:1
●● BMI. Answer: Weight (kg) / height (m2)
<18.5 underweight
18.5-24.9 normal
25-29.9 overweight
30+obese
●● Corrected Calcium (when alb <3.5, unless ionized Ca given).
Answer: Calcium reported + [(4.0-albumin) x 0.8]
●● Anion Gap. Answer: Na-Cl-HCo3
QUESTIONS WITH ANSWERS GRADED A+
●● Calculating a dose of new dosage form. Answer: dose of new dosage
form =
amount absorbed from current dosage form/F of new dosage form
●● Vd. Answer: dose/cp
(amount of drug in body/conc. of drug in plasma)
●● Cl. Answer: Rate of elim (ke) / Conc
or
F X dose / AUC
●● Elimination Rate constant. Answer: Ke = cl/vd
●● LD. Answer: desired concentration x Vd / F
, ●● t1/2. Answer: 0.693/ke
●● IBW for females. Answer: 45.5kg + (2.3kg)(# of inches over 5 feet)
●● IBW for men. Answer: 50kg + (2.3kg)(# inches over 5 feet)
●● ABW. Answer: IBW + 0.4(TBW-IBW)
●● dehydration. Answer: BUN:Scr > 20:1
●● BMI. Answer: Weight (kg) / height (m2)
<18.5 underweight
18.5-24.9 normal
25-29.9 overweight
30+obese
●● Corrected Calcium (when alb <3.5, unless ionized Ca given).
Answer: Calcium reported + [(4.0-albumin) x 0.8]
●● Anion Gap. Answer: Na-Cl-HCo3