HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP
HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP NEWEST
2026/2027 ACTUAL EXAM COMPLETE 160 QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED
A+|BRAND NEW VERSION!!
What pathophysiologic abnormality underlies systemic lupus erythematosus
(SLE)?
a. Immune deficiency
b. Type 2 hypersensitivity
c. Autoimmunity
d. Immunosuppression - Correct Answer-c. Autoimmunity
Which of the following terms best describes the symptoms of petechiae. easy
bruising, bleeding gums, occult hematuria or retinal hemorrhage?
a. Neutropenia
b. Leukopenia
c. Anemia
d. Thrombocytopenia - Correct Answer-d. Thrombocytopenia
If I get a kidney transplant from my sister, what is it called?
a. Allogenic transplant
b. 'Gift of Life'
c. Autologous transplant
1|Page
, HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP
d. peripheral stem cell transplant - Correct Answer-a. Allogenic transplant
Which of the following is a malignant disorder of mature antibody-secreting B
lymphocytes or plasma cells?
a. Multiple myeloma
b. Hairy cell leukemia
c. ALL
d. CML - Correct Answer-a. Multiple myeloma
Which disease has the presence of Reed-Sternberg cells?
a. B-cell lymphoma
b. NK-cell lymphoma
c. Hodgkin lymphoma
d. T-cell lymphoma - Correct Answer-c. Hodgkin lymphoma
Which of the following assists in the diagnosis of multiple myeloma?
a. Elevated liver enzymes
b. Bence Jones proteins
c. Hyperkalmia
d. Erythrocytosis - Correct Answer-b. Bence Jones proteins
What statement is true regarding HIV-1?
a. It is a causative agent in the US
2|Page
, HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP
b. It produces a milder form of the disease
c. It is most commonly found in West Africa
d. The latency period is longer than HIV-2 - Correct Answer-a. It is a causative
agent in the US
What is the result of increased hydrostatic pressure in blood vessels?
a. Increased levels of albumin
b. Fluid movement into interstitial space
c. Vasoconstriction
d. Hypertension - Correct Answer-b. Fluid movement into interstitial space
Which is a manifestation of left heart failure?
a. Peripheral edema
b. Increased exercise tolerance
c. Pulmonary edema
d. Paroxysmal nocturnal dyspnea (PND) - Correct Answer-c. Pulmonary edema
An initial disturbance in a system sets off a chain of events that does not favor
stability and often abruptly displaces a system from its steady state: what is that?
a. Positive Feedback
b. Negative Feedback
c. Disease
d. Homeostasis - Correct Answer-a. positive feedback
3|Page
, HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP
What organ shrinks with age?
a. Prostate
b. Gums
c. Heart
d. All of the above - Correct Answer-b. gums
Which of the following is true?
a. An infant will have a slower heart rate than an adult
b. The elderly have better temperature sensations
c. There are more sweat glands in an elderly person
d. There is less thirst perception in the elderly - Correct Answer-d. there is less
thirst perception in the elderly
Which of the following is true?
a. Women snore more than men
b. Men have higher calcium levels
c. Women have a lower hemoglobin than men
d. Men have a lower creatinine level than women - Correct Answer-c. Women
have a lower hemoglobin than men
An increase in normal adaptive response to the decreased availability of oxygen at
high altitude is termed which?
a. Circadian
b. Acclimatization
4|Page
HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP NEWEST
2026/2027 ACTUAL EXAM COMPLETE 160 QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED
A+|BRAND NEW VERSION!!
What pathophysiologic abnormality underlies systemic lupus erythematosus
(SLE)?
a. Immune deficiency
b. Type 2 hypersensitivity
c. Autoimmunity
d. Immunosuppression - Correct Answer-c. Autoimmunity
Which of the following terms best describes the symptoms of petechiae. easy
bruising, bleeding gums, occult hematuria or retinal hemorrhage?
a. Neutropenia
b. Leukopenia
c. Anemia
d. Thrombocytopenia - Correct Answer-d. Thrombocytopenia
If I get a kidney transplant from my sister, what is it called?
a. Allogenic transplant
b. 'Gift of Life'
c. Autologous transplant
1|Page
, HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP
d. peripheral stem cell transplant - Correct Answer-a. Allogenic transplant
Which of the following is a malignant disorder of mature antibody-secreting B
lymphocytes or plasma cells?
a. Multiple myeloma
b. Hairy cell leukemia
c. ALL
d. CML - Correct Answer-a. Multiple myeloma
Which disease has the presence of Reed-Sternberg cells?
a. B-cell lymphoma
b. NK-cell lymphoma
c. Hodgkin lymphoma
d. T-cell lymphoma - Correct Answer-c. Hodgkin lymphoma
Which of the following assists in the diagnosis of multiple myeloma?
a. Elevated liver enzymes
b. Bence Jones proteins
c. Hyperkalmia
d. Erythrocytosis - Correct Answer-b. Bence Jones proteins
What statement is true regarding HIV-1?
a. It is a causative agent in the US
2|Page
, HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP
b. It produces a milder form of the disease
c. It is most commonly found in West Africa
d. The latency period is longer than HIV-2 - Correct Answer-a. It is a causative
agent in the US
What is the result of increased hydrostatic pressure in blood vessels?
a. Increased levels of albumin
b. Fluid movement into interstitial space
c. Vasoconstriction
d. Hypertension - Correct Answer-b. Fluid movement into interstitial space
Which is a manifestation of left heart failure?
a. Peripheral edema
b. Increased exercise tolerance
c. Pulmonary edema
d. Paroxysmal nocturnal dyspnea (PND) - Correct Answer-c. Pulmonary edema
An initial disturbance in a system sets off a chain of events that does not favor
stability and often abruptly displaces a system from its steady state: what is that?
a. Positive Feedback
b. Negative Feedback
c. Disease
d. Homeostasis - Correct Answer-a. positive feedback
3|Page
, HESI RN ADVANCED PATHOPHYSIOLOGY EXAM PREP
What organ shrinks with age?
a. Prostate
b. Gums
c. Heart
d. All of the above - Correct Answer-b. gums
Which of the following is true?
a. An infant will have a slower heart rate than an adult
b. The elderly have better temperature sensations
c. There are more sweat glands in an elderly person
d. There is less thirst perception in the elderly - Correct Answer-d. there is less
thirst perception in the elderly
Which of the following is true?
a. Women snore more than men
b. Men have higher calcium levels
c. Women have a lower hemoglobin than men
d. Men have a lower creatinine level than women - Correct Answer-c. Women
have a lower hemoglobin than men
An increase in normal adaptive response to the decreased availability of oxygen at
high altitude is termed which?
a. Circadian
b. Acclimatization
4|Page
