, Test Bank ma
to accompany
ma
Psychopharmacology, Third Edition ma ma
Meyer • Quenzer ma ma
Chapter 1: Principles of Pharmacology ma ma ma ma
Multiple Choice ma
1. ma
refer(s) to specific molecular changes that occur when a drug binds to a particular t
ma ma ma ma ma ma ma ma ma ma ma ma ma ma
arget site or receptor, while
ma ma ma ma
are the resulting widespread alterationsin function.
ma ma ma ma m
a ma
a. Drug action; therapeutic effects
ma ma ma
b. Side effects; drug effects
ma ma ma
c. Therapeutic effects; side effects ma ma ma
d. Drug action; drug effects ma ma ma
Answer: d ma
Textbook Reference: Pharmacology: The Science of Drug Action
ma ma ma ma ma ma ma
2. After drug administration has occurred, the amount of drug in the blood that is free
ma ma ma ma ma ma ma ma ma ma ma ma ma ma ma
tobind at specific target sites is referred to as
m
a ma ma ma ma ma ma ma ma
a. the therapeutic dose.
ma ma
b. first-pass effects. ma
c. bioavailability.
d. ED50.
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
3. The specific molecular changes that occur when a drug binds to a particular target si
ma ma ma ma ma ma ma ma ma ma ma ma ma ma
teor receptor are referred to as
m
a ma ma ma ma ma
a. drug effects. ma
b. drug action. ma
c. side effects. ma
d. placebo effects. ma
Answer: b ma
Textbook Reference: Pharmacology: The Science of Drug Action
ma ma ma ma ma ma ma
4. Which of the following is not a possible explanation for placebo effects?
ma ma ma ma ma ma ma ma ma ma ma
a. Pavlovian conditioning ma
b. Genetic variation ma
c. Drug competition ma
d. Expectation of outcome ma ma
Answer: c ma
Textbook Reference: Pharmacology: The Science of Drug Action
ma ma ma ma ma ma ma
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ma ma ma
,5. The administration of oxytocin has been proposed as a treatment for autism. ma ma ma ma ma ma ma ma ma ma
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
6. Which factor does not affect the pharmacokinetics of a drug?
ma ma ma ma ma ma ma ma ma
a. Route of administration
ma ma
b. Lipid solubility
ma
c. Depot bindingma
d. Drug action
ma
Answer: d ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
7. First-pass metabolism occurs when drugs are taken
ma ma ma ma ma ma
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
8. The area postrema is one area in the brain where the
ma ma is not complete.
ma ma ma ma ma ma ma ma ma ma
a. cerebrospinal fluid ma
b. blood–brain barrier ma
c. choroid plexus ma
d. phospholipid membrane ma
Answer: b ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
9. First-pass metabolism occurs with orally administered drugs because
ma ma ma ma ma ma ma
a. their absorption is slowed by food.
ma ma ma ma ma
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
ma ma ma ma ma ma ma ma ma ma ma ma ma ma ma
togeneral circulation.
m
a ma
c. drugs must first survive the acidic environment of the stomach.
ma ma ma ma ma ma ma ma ma
d. salivary enzymes in the mouth begin the process of metabolism.
ma ma ma ma ma ma ma ma ma
Answer: b ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
10. Toxic substances in the blood trigger a vomiting response by activating the
ma ma ma ma ma ma ma ma ma ma ma
a. blood–brain barrier. ma
b. choroid plexus. ma
c. area postrema.
ma
d. median eminence. ma
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ma ma ma
, Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
11. Drugs administered _ ma have the most rapid onset of action. ma ma ma ma ma ma ma
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
12. Ionization of a drug depends on the
ma of the solution and the
ma ma ma ma ma ma ma ma ma
of thedrug.
ma m
a
a. pH; pKa
ma
b. pKa; pH ma
c. concentration; lipid solubility ma ma
d. pH; concentration
ma
Answer: a ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
13. The absorption of a drug depends on all of the following except
ma ma ma ma ma ma ma ma ma ma ma
a. lipid solubility.
ma
b. ionization.
c. body temperature.
ma
d. the concentration of the drug.
ma ma ma ma
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
14. Drugs that are ma should be avoided by women of childbearing age.
ma ma ma ma ma ma ma ma
a. teratogenic
b. able to cross the placental barrier
ma ma ma ma ma
c. psychoactive
d. highly lipid-soluble
ma
Answer: a ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
15. Agents that induce developmental abnormalities in a fetus are known as
ma ma ma ma ma ma ma ma ma ma
a. psychoactive drugs. ma
b. illicit drugs.
ma
c. teratogens.
d. placental drugs. ma
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
16. Depot binding is said to occur when drugs
ma ma ma ma ma ma ma
a. bind to their target sites.
ma ma ma ma
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ma ma ma
to accompany
ma
Psychopharmacology, Third Edition ma ma
Meyer • Quenzer ma ma
Chapter 1: Principles of Pharmacology ma ma ma ma
Multiple Choice ma
1. ma
refer(s) to specific molecular changes that occur when a drug binds to a particular t
ma ma ma ma ma ma ma ma ma ma ma ma ma ma
arget site or receptor, while
ma ma ma ma
are the resulting widespread alterationsin function.
ma ma ma ma m
a ma
a. Drug action; therapeutic effects
ma ma ma
b. Side effects; drug effects
ma ma ma
c. Therapeutic effects; side effects ma ma ma
d. Drug action; drug effects ma ma ma
Answer: d ma
Textbook Reference: Pharmacology: The Science of Drug Action
ma ma ma ma ma ma ma
2. After drug administration has occurred, the amount of drug in the blood that is free
ma ma ma ma ma ma ma ma ma ma ma ma ma ma ma
tobind at specific target sites is referred to as
m
a ma ma ma ma ma ma ma ma
a. the therapeutic dose.
ma ma
b. first-pass effects. ma
c. bioavailability.
d. ED50.
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
3. The specific molecular changes that occur when a drug binds to a particular target si
ma ma ma ma ma ma ma ma ma ma ma ma ma ma
teor receptor are referred to as
m
a ma ma ma ma ma
a. drug effects. ma
b. drug action. ma
c. side effects. ma
d. placebo effects. ma
Answer: b ma
Textbook Reference: Pharmacology: The Science of Drug Action
ma ma ma ma ma ma ma
4. Which of the following is not a possible explanation for placebo effects?
ma ma ma ma ma ma ma ma ma ma ma
a. Pavlovian conditioning ma
b. Genetic variation ma
c. Drug competition ma
d. Expectation of outcome ma ma
Answer: c ma
Textbook Reference: Pharmacology: The Science of Drug Action
ma ma ma ma ma ma ma
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ma ma ma
,5. The administration of oxytocin has been proposed as a treatment for autism. ma ma ma ma ma ma ma ma ma ma
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
6. Which factor does not affect the pharmacokinetics of a drug?
ma ma ma ma ma ma ma ma ma
a. Route of administration
ma ma
b. Lipid solubility
ma
c. Depot bindingma
d. Drug action
ma
Answer: d ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
7. First-pass metabolism occurs when drugs are taken
ma ma ma ma ma ma
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
8. The area postrema is one area in the brain where the
ma ma is not complete.
ma ma ma ma ma ma ma ma ma ma
a. cerebrospinal fluid ma
b. blood–brain barrier ma
c. choroid plexus ma
d. phospholipid membrane ma
Answer: b ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
9. First-pass metabolism occurs with orally administered drugs because
ma ma ma ma ma ma ma
a. their absorption is slowed by food.
ma ma ma ma ma
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
ma ma ma ma ma ma ma ma ma ma ma ma ma ma ma
togeneral circulation.
m
a ma
c. drugs must first survive the acidic environment of the stomach.
ma ma ma ma ma ma ma ma ma
d. salivary enzymes in the mouth begin the process of metabolism.
ma ma ma ma ma ma ma ma ma
Answer: b ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
10. Toxic substances in the blood trigger a vomiting response by activating the
ma ma ma ma ma ma ma ma ma ma ma
a. blood–brain barrier. ma
b. choroid plexus. ma
c. area postrema.
ma
d. median eminence. ma
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Page 2 of 247
ma ma ma
, Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
11. Drugs administered _ ma have the most rapid onset of action. ma ma ma ma ma ma ma
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
12. Ionization of a drug depends on the
ma of the solution and the
ma ma ma ma ma ma ma ma ma
of thedrug.
ma m
a
a. pH; pKa
ma
b. pKa; pH ma
c. concentration; lipid solubility ma ma
d. pH; concentration
ma
Answer: a ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
13. The absorption of a drug depends on all of the following except
ma ma ma ma ma ma ma ma ma ma ma
a. lipid solubility.
ma
b. ionization.
c. body temperature.
ma
d. the concentration of the drug.
ma ma ma ma
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
14. Drugs that are ma should be avoided by women of childbearing age.
ma ma ma ma ma ma ma ma
a. teratogenic
b. able to cross the placental barrier
ma ma ma ma ma
c. psychoactive
d. highly lipid-soluble
ma
Answer: a ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
15. Agents that induce developmental abnormalities in a fetus are known as
ma ma ma ma ma ma ma ma ma ma
a. psychoactive drugs. ma
b. illicit drugs.
ma
c. teratogens.
d. placental drugs. ma
Answer: c ma
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ma ma ma ma ma ma
16. Depot binding is said to occur when drugs
ma ma ma ma ma ma ma
a. bind to their target sites.
ma ma ma ma
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ma ma ma