1. Which laboratory value is most critical to assess before chemotherapy administration?
A. Hemoglobin
B. Absolute neutrophil count (ANC)
C. Blood glucose
D. Serum calcium
Correct Answer: B. Absolute neutrophil count (ANC)
Rationale: ANC determines infection risk and whether chemotherapy can be safely given.
2. Which ANC level indicates severe neutropenia?
A. >1500/mm³
B. 1000–1500/mm³
C. <500/mm³
D. >3000/mm³
Correct Answer: C. <500/mm³
Rationale: Severe neutropenia greatly increases infection risk.
3. Which condition is a priority complication of chemotherapy?
A. Neutropenic sepsis
B. Hair growth
C. Hypertension
D. Hyperthyroidism
Correct Answer: A. Neutropenic sepsis
Rationale: Immunosuppression leads to life-threatening infection.
4. Which nursing intervention is essential for neutropenic patients?
A. Strict hand hygiene and protective isolation
B. Encourage raw fruits and vegetables
C. Avoid monitoring temperature
D. Increase visitors
,Correct Answer: A. Strict hand hygiene and protective isolation
Rationale: Reduces exposure to pathogens.
5. Which temperature indicates febrile neutropenia emergency?
A. 37.0°C
B. 37.5°C
C. ≥38.0°C
D. 36.0°C
Correct Answer: C. ≥38.0°C
Rationale: Fever in neutropenic patients is a medical emergency.
6. Which intervention is priority in febrile neutropenia?
A. Start broad-spectrum IV antibiotics immediately
B. Give oral fluids only
C. Delay treatment until cultures return
D. Apply ice packs only
Correct Answer: A. Start broad-spectrum IV antibiotics immediately
Rationale: Rapid treatment reduces sepsis mortality.
7. Which chemotherapy side effect affects bone marrow most significantly?
A. Myelosuppression
B. Rash
C. Constipation only
D. Hair growth
Correct Answer: A. Myelosuppression
Rationale: Chemotherapy suppresses blood cell production.
8. Which blood cell line is most affected first in chemotherapy?
, A. Neutrophils
B. Platelets
C. Red blood cells
D. Lymphocytes only
Correct Answer: A. Neutrophils
Rationale: Neutrophils have short lifespan and decline quickly.
9. Which finding indicates thrombocytopenia?
A. Easy bruising and petechiae
B. Hypertension
C. Fever only
D. Weight gain
Correct Answer: A. Easy bruising and petechiae
Rationale: Low platelets impair clotting.
10.Which platelet level is considered high bleeding risk?
A. >150,000/mm³
B. 100,000/mm³
C. <50,000/mm³
D. >400,000/mm³
Correct Answer: C. <50,000/mm³
Rationale: Severe thrombocytopenia increases bleeding risk.
11.Which intervention is appropriate for thrombocytopenia?
A. Avoid IM injections
B. Encourage vigorous exercise
C. Use aspirin freely
D. No precautions needed
Correct Answer: A. Avoid IM injections
Rationale: Prevents bleeding complications.
A. Hemoglobin
B. Absolute neutrophil count (ANC)
C. Blood glucose
D. Serum calcium
Correct Answer: B. Absolute neutrophil count (ANC)
Rationale: ANC determines infection risk and whether chemotherapy can be safely given.
2. Which ANC level indicates severe neutropenia?
A. >1500/mm³
B. 1000–1500/mm³
C. <500/mm³
D. >3000/mm³
Correct Answer: C. <500/mm³
Rationale: Severe neutropenia greatly increases infection risk.
3. Which condition is a priority complication of chemotherapy?
A. Neutropenic sepsis
B. Hair growth
C. Hypertension
D. Hyperthyroidism
Correct Answer: A. Neutropenic sepsis
Rationale: Immunosuppression leads to life-threatening infection.
4. Which nursing intervention is essential for neutropenic patients?
A. Strict hand hygiene and protective isolation
B. Encourage raw fruits and vegetables
C. Avoid monitoring temperature
D. Increase visitors
,Correct Answer: A. Strict hand hygiene and protective isolation
Rationale: Reduces exposure to pathogens.
5. Which temperature indicates febrile neutropenia emergency?
A. 37.0°C
B. 37.5°C
C. ≥38.0°C
D. 36.0°C
Correct Answer: C. ≥38.0°C
Rationale: Fever in neutropenic patients is a medical emergency.
6. Which intervention is priority in febrile neutropenia?
A. Start broad-spectrum IV antibiotics immediately
B. Give oral fluids only
C. Delay treatment until cultures return
D. Apply ice packs only
Correct Answer: A. Start broad-spectrum IV antibiotics immediately
Rationale: Rapid treatment reduces sepsis mortality.
7. Which chemotherapy side effect affects bone marrow most significantly?
A. Myelosuppression
B. Rash
C. Constipation only
D. Hair growth
Correct Answer: A. Myelosuppression
Rationale: Chemotherapy suppresses blood cell production.
8. Which blood cell line is most affected first in chemotherapy?
, A. Neutrophils
B. Platelets
C. Red blood cells
D. Lymphocytes only
Correct Answer: A. Neutrophils
Rationale: Neutrophils have short lifespan and decline quickly.
9. Which finding indicates thrombocytopenia?
A. Easy bruising and petechiae
B. Hypertension
C. Fever only
D. Weight gain
Correct Answer: A. Easy bruising and petechiae
Rationale: Low platelets impair clotting.
10.Which platelet level is considered high bleeding risk?
A. >150,000/mm³
B. 100,000/mm³
C. <50,000/mm³
D. >400,000/mm³
Correct Answer: C. <50,000/mm³
Rationale: Severe thrombocytopenia increases bleeding risk.
11.Which intervention is appropriate for thrombocytopenia?
A. Avoid IM injections
B. Encourage vigorous exercise
C. Use aspirin freely
D. No precautions needed
Correct Answer: A. Avoid IM injections
Rationale: Prevents bleeding complications.
