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HESI Exit Exam Study Guide PDF | RN Nursing Exit Exam Questions and Answers | NCLEX Preparation & Review 2026

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Prepare confidently for your nursing exit exams with the HESI Exit Exam Study Guide PDF, a comprehensive resource designed for RN and PN nursing students. This study guide includes practice questions, verified answers, detailed rationales, and NCLEX-style review materials to help improve clinical judgment and exam performance. Ideal for nursing students in the USA, UK, Canada, Australia, and Europe, this guide supports success in the HESI Exit Exam and strengthens readiness for the Next Generation NCLEX (NGN).

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Institution
Nursing Course
Course
Nursing course

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HESI Exit Exam Study Guide
Labs:ormal Values:
HgB: - Males:
• 14-18
- Female:
• 12-16
Hct: - Males:
• 42-52
- Female:
• 37-47
RBC’s: - Males:
• 4.7-6.1 million
- Female:
• 4.2-5.4 million
WBC’s: - 4.5-11k
Platelets: - 150-400k
PT: - 11-12.5 seconds
INR: - 1.5-2.5 times normal
APTT: - 60-70 seconds
BUN: - 10-20
Creatinine: - 0.5-1.2
Glucose: - 70-110
Cholesterol: - <200
Bilirubin Newborn: - 1-12
Phenylalanine: - Newborn: <2
- Adult: <6
Na: - 135-145
K: - 3.5-5.0
- Hypokalemia:
• Prominent U waves
• Depressed ST segment
• Flat T waves
- Hyperkalemia:
• Tall T-Waves
• Prolonged PR interval
• Wide QRS




HESI Exit Exam Study Guide

,HESI Exit Exam Study Guide

Ca: - 9-10.5
- Hypocalcemia:
• Muscle spasms
• Convulsions
• Cramps/tetany
• Trousseau’s
+ Chvostek’s
• Prolonged ST interval
• Prolonged QT segment
Mg: - 1.5-2.5
Cl: - 96-106
Phosphate: - 3-4.5
Albumin: - 3.5-5
Specific Gravity: - 1.003-1.030
A1c: - 4-6% is ideal
- <7.5= OK
- This tells you average blood glucose over 120 days
Dilantin: - 10-20
Lithium: - 0.5-1.5
ABGs: - Used in acidosis v alkalosis
- PH:
• 7.35-7.45
- CO2:
• 35-45  Respiratory Driver
- HCO3:
• 21-28  Metabolic Driver
- O2:
• 80-100
- O2 STAT:
• 95-100%




HESI Exit Exam Study Guide

, HESI Exit Exam Study Guide

Antidotes
Antidotes:
1. Digoxin Digibond
2. Coumadin Vitamin K ( Keep PT and INR @ 1-1.5 X
Normal)
3. Benzodiazepines Flumazenil (Romazicon)
4. Magnesium Sulfate Calcium Gluconate
5. Heparin Protamine Sulfate (Keep APTT and PTT @
1.5-2.5 X Normal)
6. Tylenol Mucomyst (17 doses + Loading Dose)
7. Opiates (Narcotic analgesics, heroin, morphine)
Narcan (Naloxone)
8. Cholinergic Meds (Myasthenic Bradycardia)
atropine
9. Methotrexate Leucovorin

Delegation:
Delegation:
RN Only: - Blood Products  2 RN’s Must Check
- Clotting Factors
- Sterile Dressing changes and procedures
- Assessment that require clinical judgment
- Ultimately responsible for all delegated duties
UAP: - Non-sterile procedures




HESI Exit Exam Study Guide

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Nursing course

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Written in
2025/2026
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