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CMC Certification Exam Mastery Guide: 100 AACN Cardiac Medicine Practice Questions with Detailed Rationales (2026 Updated Edition)

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Prepare confidently for the AACN Cardiac Medicine Certification (CMC) exam with this comprehensive review guide designed specifically for critical care nurses, cardiac nurses, ICU nurses, progressive care nurses, and advanced RN learners. This high-yield exam prep workbook includes realistic certification-style practice questions, detailed rationales, and essential cardiac nursing concepts to strengthen clinical judgment and improve test performance.

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Institution
CMC CERTIFICATIOAN EXA
Course
CMC CERTIFICATIOAN EXA

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CMC CERTIFICATION EXAM MASTERY GUIDE: 100 AACN CARDIAC MEDICINE PRACTICE
QUESTIONS WITH DETAILED RATIONALES (2026 UPDATED EDITION)




Question 1

A patient with acute myocardial infarction develops chest pain unrelieved by nitroglycerin.
What is the nurse’s priority action?

A. Encourage ambulation
B. Notify the provider immediately
C. Reassess in 2 hours
D. Restrict oxygen therapy

Correct Answer: B. Notify the provider immediately

Rationale:

Persistent chest pain despite nitroglycerin may indicate ongoing myocardial ischemia or
infarction requiring urgent intervention.

Potential treatments include:

• Additional anti-ischemic therapy

• Cardiac catheterization

• Reperfusion procedures

Prompt action helps reduce myocardial damage.



Question 2

Which assessment finding is most consistent with left-sided heart failure?

A. Ascites
B. Peripheral edema

,C. Pulmonary crackles
D. Jugular venous distention

Correct Answer: C. Pulmonary crackles

Rationale:

Left-sided heart failure causes fluid backup into the lungs, leading to pulmonary congestion.

Common findings include:

• Crackles

• Dyspnea

• Orthopnea

• Pulmonary edema

Peripheral edema is more commonly associated with right-sided heart failure.



Question 3

A patient develops ventricular fibrillation on the cardiac monitor. What is the nurse’s first
action?

A. Obtain blood pressure
B. Begin chest compressions
C. Immediate defibrillation
D. Administer atropine

Correct Answer: C. Immediate defibrillation

Rationale:

Ventricular fibrillation is a life-threatening pulseless rhythm requiring immediate
defibrillation.

Rapid defibrillation greatly improves survival rates.

CPR should continue until the defibrillator is ready.



Question 4

Which laboratory value is most specific for myocardial injury?

,A. BNP
B. Troponin
C. Potassium
D. Hemoglobin

Correct Answer: B. Troponin

Rationale:

Troponin is the most specific and sensitive biomarker for myocardial injury.

Elevated levels strongly suggest:

• Acute myocardial infarction

• Myocardial damage



Question 5

A patient with atrial fibrillation is at greatest risk for:

A. Pulmonary fibrosis
B. Stroke
C. Pneumothorax
D. Hypercalcemia

Correct Answer: B. Stroke

Rationale:

Atrial fibrillation causes ineffective atrial contractions, increasing the risk of thrombus
formation and embolic stroke.

Anticoagulation therapy is often required.



Question 6

Which medication is commonly administered for symptomatic bradycardia?

A. Adenosine
B. Atropine
C. Digoxin
D. Lidocaine

, Correct Answer: B. Atropine

Rationale:

Atropine increases heart rate by blocking vagal stimulation to the heart.

It is first-line treatment for symptomatic bradycardia.



Question 7

A patient with heart failure has gained 3 pounds in 24 hours. What should the nurse suspect?

A. Fluid retention
B. Dehydration
C. Improved cardiac output
D. Hyperthyroidism

Correct Answer: A. Fluid retention

Rationale:

Rapid weight gain in heart failure commonly indicates fluid accumulation.

Other findings may include:

• Edema

• Crackles

• Dyspnea

Daily weight monitoring is essential.



Question 8

Which ECG finding is commonly associated with hyperkalemia?

A. U waves
B. Peaked T waves
C. Prolonged QT interval
D. ST depression only

Correct Answer: B. Peaked T waves

Rationale:

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Institution
CMC CERTIFICATIOAN EXA
Course
CMC CERTIFICATIOAN EXA

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Uploaded on
May 20, 2026
Number of pages
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Written in
2025/2026
Type
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