NUCLEAR MEDICINE LATEST 2026 TEST PAPER QUESTIONS
AND SOLUTIONS GUARANTEE A+
✔✔When is dobutamine recommended as a stress agent? - ✔✔Patients who can't
undergo stress testing and have contraindications to pharmacological vasodilator
✔✔What medication is used to evaluate for cerebrovascular reserve? -
✔✔Acetazolamide (vasodilator which crosses BBB) Trade name Diamox Used in TIA,
completed stroke or vascular anomalies to distinguish vascular from neuronal dementia
✔✔What two tracers show uptake in the liver spleen and bone marrow only? - ✔✔In-
111 WBC Tc-99m SC
✔✔What is scanning performed for In-111 WBC - ✔✔Typically at 24 h May also image
earlier at 4h (medium energy)
✔✔Which cells does Tc99m petechnetate localizes in which stomach cells? -
✔✔Mucous producing cells
✔✔What is carcinoid syndrome? What does one usually have before diarrhea occurs? -
✔✔Paroxysmal vasomotor disturbance Diarrhea Bronchocpasm Flushing
✔✔What is a RAD? - ✔✔Radiation absorbed dose Measure of absorbed dose 1 RAD =
deposition of 100 ergs of energy in 1gm of any material from any type of radiation
✔✔What is In-111 pantreotide? What is it used for? - ✔✔Somatostatin analogue
Obtained at 4 and 24 h Binds to tumors like: carcinoid, pheochromocytoma, insulinoma,
Gastrinoma
✔✔What's injected into the thecal space to look for leak? - ✔✔In-111 DTPA
✔✔In nuclear medicine what is the rim sign - ✔✔Gangrenous cholecystitis on
hepatobilliary imaging
✔✔What is the lambda sign? - ✔✔Gallium scan uptake in mediastinum in setting of
sarcoidosis
✔✔What entity will sometimes show a target sign on bone scan - ✔✔Osteoid osteoma
✔✔What's the half life of I-131 NaI? - ✔✔8 days
✔✔What is the half life of xenon-133 - ✔✔5.3 days
✔✔What is the half life of F18 - ✔✔109 min
, ✔✔How often is linearity checked on a dose calibrator? - ✔✔Quarterly
✔✔What is the dose limit of the lens for occupational workers? - ✔✔15 rem (0.15 Sv)
✔✔What is the characteristic uptake of FDG in Lewy body dimensia? - ✔✔Decreased
Occipital lobe
✔✔What renal agent can be used to assess renal tubular function? - ✔✔Tc-99 Mag3.
Cleared essentially by renal tubules
✔✔What's the mechanism of uptake for Tc-99 tetrofosmin - ✔✔Passive diffusion
✔✔When is it normal to have diffuse iodine uptake in the liver following thyroid radio
ablation? - ✔✔Immediately after. Due to thyroid protein metabolism
✔✔What's the half life of I-123 NaI - ✔✔13 hours
✔✔What is the half life of xenon133? - ✔✔5.3 days
✔✔What entities will not uptake gallium in an anterior mediastinal mass: -lymphoma -
sarcoid -Kaposi sarcoma - ✔✔Kaposi sarcoma will not uptake gallium in the
mediastinum
✔✔2 Pagets manifestations in skull - ✔✔osteoporosis circumpscripta cotton wool also
accociated with basilar invagination neuroforaminal narrowing
✔✔Super scan DDx - ✔✔Mets : breast, prostate, lung Metaoblic: Hyperparathyroidism,
renal osteodystophy, osteomalacia Other: Mastocytosis, Myelofibrosis
✔✔Is gallium or indiumWBC a better tool for lung infections - ✔✔Gallium
In-111 had background uptake in lungs for up to 4 hours
✔✔What's a common cause of hydrolyzed Tc-99m contaminant - ✔✔Air exposure
✔✔What timeframe of gb visualization in hida excludes acute cholecystitis - ✔✔60 min
✔✔Is gall bladder uptake normal with FDG pet? - ✔✔No- uptake suggests cholecystitis
or a neoplastic process
✔✔What is a major concern with use of radioisotopes and treatment of metastatic bone
disease? - ✔✔Myelosupression
AND SOLUTIONS GUARANTEE A+
✔✔When is dobutamine recommended as a stress agent? - ✔✔Patients who can't
undergo stress testing and have contraindications to pharmacological vasodilator
✔✔What medication is used to evaluate for cerebrovascular reserve? -
✔✔Acetazolamide (vasodilator which crosses BBB) Trade name Diamox Used in TIA,
completed stroke or vascular anomalies to distinguish vascular from neuronal dementia
✔✔What two tracers show uptake in the liver spleen and bone marrow only? - ✔✔In-
111 WBC Tc-99m SC
✔✔What is scanning performed for In-111 WBC - ✔✔Typically at 24 h May also image
earlier at 4h (medium energy)
✔✔Which cells does Tc99m petechnetate localizes in which stomach cells? -
✔✔Mucous producing cells
✔✔What is carcinoid syndrome? What does one usually have before diarrhea occurs? -
✔✔Paroxysmal vasomotor disturbance Diarrhea Bronchocpasm Flushing
✔✔What is a RAD? - ✔✔Radiation absorbed dose Measure of absorbed dose 1 RAD =
deposition of 100 ergs of energy in 1gm of any material from any type of radiation
✔✔What is In-111 pantreotide? What is it used for? - ✔✔Somatostatin analogue
Obtained at 4 and 24 h Binds to tumors like: carcinoid, pheochromocytoma, insulinoma,
Gastrinoma
✔✔What's injected into the thecal space to look for leak? - ✔✔In-111 DTPA
✔✔In nuclear medicine what is the rim sign - ✔✔Gangrenous cholecystitis on
hepatobilliary imaging
✔✔What is the lambda sign? - ✔✔Gallium scan uptake in mediastinum in setting of
sarcoidosis
✔✔What entity will sometimes show a target sign on bone scan - ✔✔Osteoid osteoma
✔✔What's the half life of I-131 NaI? - ✔✔8 days
✔✔What is the half life of xenon-133 - ✔✔5.3 days
✔✔What is the half life of F18 - ✔✔109 min
, ✔✔How often is linearity checked on a dose calibrator? - ✔✔Quarterly
✔✔What is the dose limit of the lens for occupational workers? - ✔✔15 rem (0.15 Sv)
✔✔What is the characteristic uptake of FDG in Lewy body dimensia? - ✔✔Decreased
Occipital lobe
✔✔What renal agent can be used to assess renal tubular function? - ✔✔Tc-99 Mag3.
Cleared essentially by renal tubules
✔✔What's the mechanism of uptake for Tc-99 tetrofosmin - ✔✔Passive diffusion
✔✔When is it normal to have diffuse iodine uptake in the liver following thyroid radio
ablation? - ✔✔Immediately after. Due to thyroid protein metabolism
✔✔What's the half life of I-123 NaI - ✔✔13 hours
✔✔What is the half life of xenon133? - ✔✔5.3 days
✔✔What entities will not uptake gallium in an anterior mediastinal mass: -lymphoma -
sarcoid -Kaposi sarcoma - ✔✔Kaposi sarcoma will not uptake gallium in the
mediastinum
✔✔2 Pagets manifestations in skull - ✔✔osteoporosis circumpscripta cotton wool also
accociated with basilar invagination neuroforaminal narrowing
✔✔Super scan DDx - ✔✔Mets : breast, prostate, lung Metaoblic: Hyperparathyroidism,
renal osteodystophy, osteomalacia Other: Mastocytosis, Myelofibrosis
✔✔Is gallium or indiumWBC a better tool for lung infections - ✔✔Gallium
In-111 had background uptake in lungs for up to 4 hours
✔✔What's a common cause of hydrolyzed Tc-99m contaminant - ✔✔Air exposure
✔✔What timeframe of gb visualization in hida excludes acute cholecystitis - ✔✔60 min
✔✔Is gall bladder uptake normal with FDG pet? - ✔✔No- uptake suggests cholecystitis
or a neoplastic process
✔✔What is a major concern with use of radioisotopes and treatment of metastatic bone
disease? - ✔✔Myelosupression
