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MSN 671 NEI GLOBAL VIDEO COMPETENCY REVIEW 2026 MOCK TEST COMPLETE KEY INSIGHTS

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MSN 671 NEI GLOBAL VIDEO COMPETENCY REVIEW 2026 MOCK TEST COMPLETE KEY INSIGHTS

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MSN 671 NEI GLOBAL VIDEO COMPETENCY
REVIEW 2026 MOCK TEST COMPLETE KEY
INSIGHTS

◉ Key metabolic labs before starting antipsychotics.
Answer: CBC, CMP, A1C, lipids, weight/BMI, vitals, ECG.


◉ SGAs with most metabolic risk.
Answer: Olanzapine, clozapine.


◉ Antipsychotics causing most prolactin elevation.
Answer: Risperidone and paliperidone.


◉ TCAs lethal in overdose.
Answer: Cardiac sodium channel blockade → fatal arrhythmias.


◉ SSRI mechanism of action.
Answer: Block SERT, ↑ serotonin in cleft.


◉ Why SSRIs take weeks to work.

, Answer: Delayed 5-HT1A autoreceptor desensitization → increased
serotonin release.


◉ SSRI with longest half-life.
Answer: Fluoxetine (Prozac) (4-16 days metabolite).


◉ SSRI with worst withdrawal.
Answer: Paroxetine (Paxil).


◉ Low-dose vs high-dose trazodone effects.
Answer: Low: H1 + α1 block → sedation; High: SERT inhibition →
antidepressant.


◉ Age group with highest suicidality risk from antidepressants.
Answer: Children 6-12.


◉ Washout needed when switching SSRI → MAOI.
Answer: 2 weeks (except fluoxetine: 5 weeks).


◉ MAOI diet restrictions.
Answer: No tyramine (aged/fermented foods).

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