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NCLEX-RN Comprehensive Practice Exam Review Guide 2025–2026 – High-Yield Nursing Concepts, Clinical Judgment & Exam Preparation Notes

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This NCLEX-RN review guide is designed to support nursing students preparing for comprehensive exit exams and the NCLEX-RN. It provides structured, high-yield content aligned with current NCLEX test plans and Next Generation NCLEX (NGN) expectations. The material focuses on essential nursing knowledge areas including safety and infection control, pharmacology fundamentals, prioritization and delegation, leadership and management, and medical-surgical nursing concepts. It also includes clinical judgment frameworks to strengthen decision-making skills in complex patient care scenarios. This guide is intended for educational review and conceptual understanding, not as a reproduction of actual exam questions or proprietary test content

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RN Comprehensive Online Practice Exam B (2026–2027) –
NCLEX-RN Practice Questions and Verified Answers | Latest
Updated Review & Study Guide


A nurse is caring for a 5-year-old child


Physical Examination:
1510:
Upon visual inspection, throat is inflamed, tonsils appear pink, reddened and
epiglottis is edematous and cherry red in appearance. Skin appears pale. Stridor
noted upon inspiration with diminished bilateral lung sounds.


Nurse's Notes:
1500
Child accompanied to emergency department by caregiver. Caregiver states child
has a sore throat and reports the child has "pain on swallowing" and denies cough.
Child is agitated and lean - CORRECT ANSWER -Condition: Epiglottis
Actions: Initiate droplet precautions and request a prescription for IV antibiotics
Monitors: Breath sounds and temperature


The nurse should anticipate initiating droplet precautions and requesting a
prescription for IV antibiotics. The child is most likely experiencing epiglottis
because of the clinical manifestations of a high fever, inflammation and redness of
the throat, pale skin, stridor with inspiration, painful swallowing, no cough, is sitting
in tripod position, and drooling. The nurse should monitor the child's temperature
and breath sounds.

,A nurse is caring for a client who is on the spinal cord injury (SCI) unit


Nurses' Notes
Day 3, 1700
Client admitted to SCI unit 3 days ago following C7 injury. Skin is cool, pale, and
dry to touch. Respirations easy and unlabored. Lung sounds diminished in lower
lobes. Abdomen soft and nondistended with active bowel sounds. Client passed a
small amount of hard formed stool this AM. Indwelling urinary catheter draining
clear yellow urine. Deep tendon reflexes (DTR) are biceps 1+, triceps 1+, pa -
CORRECT ANSWER -The client is most likely experiencing manifestations of
pneumonia and autonomic dysreflexia.


The nurse should analyze cues from the client's manifestations and determine that
the client is most likely experiencing manifestations of pneumonia and autonomic
dysreflexia. A client who has a cervical SCI is at risk for respiratory complications
because spinal innervation to the respiratory muscles is disrupted. Adventitious
breath sounds in the lower lobes bilaterally and a decrease in oxygen saturation to
less than 92% can indicate pneumonia. The client's sudden increase in blood
pressure, bradycardia, flushing of the skin above the area of the injury, headache,
and blurred vision are manifestations of autonomic dysreflexia, which can be a life-
threatening condition.


A nurse is caring for a client who has abdominal pain


Nurses' Notes
0900
Client reports loss of appetite, weight loss, and fatigue for 1 week. Reports
abdominal pain, 6 on a scale from 0 to 10, for 2 days. Client is a perioperative
nurse, returned 1 week ago from a 2-week mission trip to an underdeveloped
country

,1200
Results of antibody studies obtained. Provider prescription for antiviral medication
pending.


Physical Examination
0930
Lung sounds clear bilaterally. Skin warm to touch and jau - CORRECT ANSWER -
Hepatitis A: Client's risk from fecal-oral transmission, laboratory results, and
physical examination findings


Hepatitis B: Antiviral treatment, laboratory results, client's risk from bloodborne
transmission, physical examination findings


Hepatitis C: Antiviral treatment, laboratory results, client's risk from bloodborne
transmission, and physical examination findings


When analyzing cues, the nurse should recognize that manifestations of hepatitis A,
hepatitis B, and hepatitis C include jaundice, yellow sclerae, right upper quandrant
pain upon palpation, dark yellow urine, and elevated AST and ALT levels. When
analyzing cues, the nurse should also recognize the client's risk for contracting
hepatitis A through the fecal-oral route during recent travel to an underdeveloped
country and the client's occupational risk as a perioperative nurse for contracting
hepatitis B and hepatitis C through bloodborne transmission. The nurse should
recognize that the current standard of practice for


A nurse is caring for a client on a medical-surgical unit


Vital Signs

, 0700
Temperature 37.6 C (99.7 F)
Heart rate 100/min
Respiratory rate 22/min
Blood pressure 115/70 mmHg
Oxygen saturation 98% on room air


Nurses' Notes
1100
Client alert and oriented to person, place, and time. Client had episode of
diarrhea, provided perineal care. Noted 2 cm x 2 cm (0.8 in x 0.8 in) painful
edematous area on sacrum. Client repositioned every 4 hr. - CORRECT ANSWER -
Click to highlight the findings that require follow up. To deselect a finding, click on
the finding again.
- Noted 2 cm x 2 cm (0.8 in x 0.8 in) painful edematous area on sacrum
- Client repositioned every 4 hr


When recognizing cues, the nurse should determine that the client's painful
edematous area on their sacrum and that the client has only been repositioned
every 4 hr requires follow up. The client has manifestations of a pressure injury that
need to be addressed. The client should be repositioned at least every 2 hr to
prevent worsening of the pressure injury and to relieve pressure from the sacral
area.


A nurse in an outpatient mental health clinic is caring for a client


Vital Signs
3 months ago

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