COMSAE Phase 2 Cognitive Evaluation Form B
Questions With Correct Answers (Verified
Answers) Plus Rationales 2026 Q&A | Instant
Download Pdf
1
A 55-year-old man presents with chest pain radiating to the left arm.
ECG shows ST-segment elevation in leads II, III, and aVF. Which coronary
artery is most likely occluded?
A. Left anterior descending artery
B. Left circumflex artery
C. Right coronary artery
D. Posterior descending artery
Answer: C
Rationale: Inferior wall MI (II, III, aVF) is most commonly due to
occlusion of the right coronary artery, which typically supplies the AV
node and inferior myocardium.
,2
A patient presents with fatigue, pallor, and a hemoglobin of 8 g/dL.
MCV is 68 fL. Which condition is most likely?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Aplastic anemia
D. Sickle cell anemia
Answer: B
Rationale: Microcytic anemia with low MCV is most commonly due to
iron deficiency, often from chronic blood loss or inadequate intake.
3
A 23-year-old woman presents with tremor, weight loss, and heat
intolerance. Labs show low TSH and high free T4. What is the most likely
diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
C. Thyroid cancer
D. Secondary hypothyroidism
,Answer: B
Rationale: Graves disease causes hyperthyroidism with suppressed
TSH and elevated T4 due to thyroid-stimulating immunoglobulins.
4
A child presents with edema, proteinuria, and hypoalbuminemia. What
is the most likely diagnosis?
A. Nephritic syndrome
B. Nephrotic syndrome
C. Acute tubular necrosis
D. Pyelonephritis
Answer: B
Rationale: Nephrotic syndrome is characterized by heavy protein loss
leading to hypoalbuminemia and edema.
5
A patient has sudden severe flank pain radiating to the groin. Urinalysis
shows hematuria. Most likely diagnosis?
, A. Pyelonephritis
B. Kidney stones
C. Bladder cancer
D. Appendicitis
Answer: B
Rationale: Ureteral obstruction by a renal calculus classically causes
colicky flank pain and hematuria.
6
Which hormone is responsible for increasing calcium reabsorption in
the kidney?
A. Calcitonin
B. Parathyroid hormone
C. Aldosterone
D. ADH
Answer: B
Rationale: PTH increases serum calcium by increasing renal
reabsorption, bone resorption, and activating vitamin D.
Questions With Correct Answers (Verified
Answers) Plus Rationales 2026 Q&A | Instant
Download Pdf
1
A 55-year-old man presents with chest pain radiating to the left arm.
ECG shows ST-segment elevation in leads II, III, and aVF. Which coronary
artery is most likely occluded?
A. Left anterior descending artery
B. Left circumflex artery
C. Right coronary artery
D. Posterior descending artery
Answer: C
Rationale: Inferior wall MI (II, III, aVF) is most commonly due to
occlusion of the right coronary artery, which typically supplies the AV
node and inferior myocardium.
,2
A patient presents with fatigue, pallor, and a hemoglobin of 8 g/dL.
MCV is 68 fL. Which condition is most likely?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Aplastic anemia
D. Sickle cell anemia
Answer: B
Rationale: Microcytic anemia with low MCV is most commonly due to
iron deficiency, often from chronic blood loss or inadequate intake.
3
A 23-year-old woman presents with tremor, weight loss, and heat
intolerance. Labs show low TSH and high free T4. What is the most likely
diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
C. Thyroid cancer
D. Secondary hypothyroidism
,Answer: B
Rationale: Graves disease causes hyperthyroidism with suppressed
TSH and elevated T4 due to thyroid-stimulating immunoglobulins.
4
A child presents with edema, proteinuria, and hypoalbuminemia. What
is the most likely diagnosis?
A. Nephritic syndrome
B. Nephrotic syndrome
C. Acute tubular necrosis
D. Pyelonephritis
Answer: B
Rationale: Nephrotic syndrome is characterized by heavy protein loss
leading to hypoalbuminemia and edema.
5
A patient has sudden severe flank pain radiating to the groin. Urinalysis
shows hematuria. Most likely diagnosis?
, A. Pyelonephritis
B. Kidney stones
C. Bladder cancer
D. Appendicitis
Answer: B
Rationale: Ureteral obstruction by a renal calculus classically causes
colicky flank pain and hematuria.
6
Which hormone is responsible for increasing calcium reabsorption in
the kidney?
A. Calcitonin
B. Parathyroid hormone
C. Aldosterone
D. ADH
Answer: B
Rationale: PTH increases serum calcium by increasing renal
reabsorption, bone resorption, and activating vitamin D.
