Nurs 615 Pharm Exam 1 – Maryville Updated
Questions and Answers (2026) | Latest Practice
Review with Detailed Explanations | Grade A+
• 6 steps in rational drug prescribing -✓✓Define problem, specify therapeutic
objective, choose therapy, initiate therapy, educate patient, monitor & adjust.
• WHO prescribing process -✓✓Diagnose, define goal, select treatment, initiate
treatment, educate patient, monitor/adjust.
• Off-label prescribing -✓✓Using a drug for an unapproved indication, dose, or
population.
• Reasons for off-label prescribing -✓✓Clinical evidence supports use, few
approved alternatives, provider judgment.
• FDA regulation -✓✓Drug safety, efficacy, labeling, manufacturing, marketing.
• Non-regulated by FDA -✓✓Prescribing decisions by licensed practitioners or off-
label use.
• Pharmacodynamics -✓✓Study of drug effects on the body.
• Drug-receptor binding -✓✓The interaction between a drug and cellular receptor
to produce a response.
• Agonist -✓✓A drug that activates a receptor to produce a response.
, • Antagonist -✓✓A drug that blocks receptor activation.
• Affinity, efficacy, and potency -✓✓Affinity = binding strength; Efficacy = max
effect; Potency = dose needed for effect.
• 4 processes in pharmacokinetics -✓✓Absorption, distribution, metabolism,
excretion (ADME).
• Drug absorption -✓✓Most drugs are absorbed through passive diffusion.
• Factors favoring passive diffusion -✓✓Lipid solubility, small size, non-ionized
form.
• Factors affecting gastric absorption -✓✓pH, food, gastric emptying, drug
formulation.
• First-pass metabolism -✓✓Liver metabolism before systemic circulation,
reducing drug bioavailability.
• Factors affecting drug distribution -✓✓Solubility, molecular size, pH, protein
binding.
• Importance of lipid solubility -✓✓Lipid-soluble drugs cross membranes more
easily.
• Protein binding of drugs -✓✓Most drugs bind to albumin.
Questions and Answers (2026) | Latest Practice
Review with Detailed Explanations | Grade A+
• 6 steps in rational drug prescribing -✓✓Define problem, specify therapeutic
objective, choose therapy, initiate therapy, educate patient, monitor & adjust.
• WHO prescribing process -✓✓Diagnose, define goal, select treatment, initiate
treatment, educate patient, monitor/adjust.
• Off-label prescribing -✓✓Using a drug for an unapproved indication, dose, or
population.
• Reasons for off-label prescribing -✓✓Clinical evidence supports use, few
approved alternatives, provider judgment.
• FDA regulation -✓✓Drug safety, efficacy, labeling, manufacturing, marketing.
• Non-regulated by FDA -✓✓Prescribing decisions by licensed practitioners or off-
label use.
• Pharmacodynamics -✓✓Study of drug effects on the body.
• Drug-receptor binding -✓✓The interaction between a drug and cellular receptor
to produce a response.
• Agonist -✓✓A drug that activates a receptor to produce a response.
, • Antagonist -✓✓A drug that blocks receptor activation.
• Affinity, efficacy, and potency -✓✓Affinity = binding strength; Efficacy = max
effect; Potency = dose needed for effect.
• 4 processes in pharmacokinetics -✓✓Absorption, distribution, metabolism,
excretion (ADME).
• Drug absorption -✓✓Most drugs are absorbed through passive diffusion.
• Factors favoring passive diffusion -✓✓Lipid solubility, small size, non-ionized
form.
• Factors affecting gastric absorption -✓✓pH, food, gastric emptying, drug
formulation.
• First-pass metabolism -✓✓Liver metabolism before systemic circulation,
reducing drug bioavailability.
• Factors affecting drug distribution -✓✓Solubility, molecular size, pH, protein
binding.
• Importance of lipid solubility -✓✓Lipid-soluble drugs cross membranes more
easily.
• Protein binding of drugs -✓✓Most drugs bind to albumin.
