ATI Pharmacology Proctored Review Latest Update 2026
| Exam Prep | High-Yield Review Guide
1. Beta blockers should be used cautiously in patients with which of the
following conditions?
Heart failure
Pulmonary embolism
Asthma
Coronary artery disease
2. What dietary component is recommended to be increased for patients taking
Lasix?
Potassium
Sodium
Calcium
Magnesium
3. Lisinopril, an ACE inhibitor, primarily exerts its therapeutic effect by:
Inhibiting the renin-angiotensin-aldosterone system
Dilating coronary arteries
Blocking beta-adrenergic receptors
Reducing serum cholesterol levels
4. Describe the significance of the route of administration for NEUPOGEN
(filgrastim) in patient care.
The intravenous route is preferred for immediate effects.
, Intramuscular injections are less painful for patients.
Oral administration is more effective for this medication.
The subcutaneous route allows for easier administration and better
patient compliance.
5. The Food and Drug Administration recently issued a warning on the use of
SSRIs with regard to children, adolescents, and young adults with depression.
This message warned of an increased risk for
sleep disorders.
suicidal ideation.
eating disorders.
attention-deficit disorder.
6. Describe the steps you would follow to ensure proper administration of
medication via a transdermal patch, and explain the importance of each step.
Properly clean, place, and label the patch according to instructions
to ensure absorption and safety.
The transdermal patch can be applied over clothing for ease of use.
Apply the patch to any clean skin surface for convenience.
Ensure the patient takes oral medications to complement the patch.
7. Describe the mechanism by which naloxone counteracts the effects of
opiates in an overdose situation.
Naloxone works by binding to opioid receptors, displacing the
opiate and reversing its effects.
Naloxone increases the production of endorphins to counteract
opiates.
, Naloxone enhances the metabolism of opiates in the liver.
Naloxone inhibits the synthesis of opiates in the body.
8. A patient presents with severe respiratory depression after taking an
overdose of a benzodiazepine. What would be the most appropriate
immediate treatment?
Administer flumazenil
Perform gastric lavage
Administer naloxone
Provide supplemental oxygen
9. Describe the role of N-acetylcysteine in treating Tylenol overdose.
N-acetylcysteine acts as an antidote by replenishing glutathione
levels, which helps to detoxify the harmful metabolites of Tylenol.
N-acetylcysteine neutralizes the Tylenol directly in the bloodstream.
N-acetylcysteine increases the absorption of Tylenol in the liver.
N-acetylcysteine prevents the conversion of Tylenol into its active
form.
10. Discuss why diuretics are contraindicated when a patient is prescribed
lithium.
Diuretics can increase lithium levels in the blood, leading to
toxicity.
Diuretics have no effect on lithium levels.
Diuretics are used to counteract the side effects of lithium.
Diuretics enhance the effectiveness of lithium in treating bipolar
disorder.
, 11. Which of the following is the most important consideration in patients taking
lithium?
1/2 of fluid given in first 8 hours
monitor plasma levels
inuse IV over 60 minutes
must administer with cilastatin
monitor vital signs
prevent with antihistamines
12. Long-term use of steroids can cause all of the following side effects except:
Bruising
Hypotension
Moon face
Osteoporosis
13. Pregabalin (Lyrica), used in the management of diabetes mellitus, will benefit
a patient in which of the following areas?
Peripheral neuropathy
Retinopathy
Nephropathy
Diabetic diarrhea
Gastric autonomic neuropathy
14. A pt arrives at the emergency room immediately following a tylenol
overdose. Which of the following drugs should you prepare to administer?
| Exam Prep | High-Yield Review Guide
1. Beta blockers should be used cautiously in patients with which of the
following conditions?
Heart failure
Pulmonary embolism
Asthma
Coronary artery disease
2. What dietary component is recommended to be increased for patients taking
Lasix?
Potassium
Sodium
Calcium
Magnesium
3. Lisinopril, an ACE inhibitor, primarily exerts its therapeutic effect by:
Inhibiting the renin-angiotensin-aldosterone system
Dilating coronary arteries
Blocking beta-adrenergic receptors
Reducing serum cholesterol levels
4. Describe the significance of the route of administration for NEUPOGEN
(filgrastim) in patient care.
The intravenous route is preferred for immediate effects.
, Intramuscular injections are less painful for patients.
Oral administration is more effective for this medication.
The subcutaneous route allows for easier administration and better
patient compliance.
5. The Food and Drug Administration recently issued a warning on the use of
SSRIs with regard to children, adolescents, and young adults with depression.
This message warned of an increased risk for
sleep disorders.
suicidal ideation.
eating disorders.
attention-deficit disorder.
6. Describe the steps you would follow to ensure proper administration of
medication via a transdermal patch, and explain the importance of each step.
Properly clean, place, and label the patch according to instructions
to ensure absorption and safety.
The transdermal patch can be applied over clothing for ease of use.
Apply the patch to any clean skin surface for convenience.
Ensure the patient takes oral medications to complement the patch.
7. Describe the mechanism by which naloxone counteracts the effects of
opiates in an overdose situation.
Naloxone works by binding to opioid receptors, displacing the
opiate and reversing its effects.
Naloxone increases the production of endorphins to counteract
opiates.
, Naloxone enhances the metabolism of opiates in the liver.
Naloxone inhibits the synthesis of opiates in the body.
8. A patient presents with severe respiratory depression after taking an
overdose of a benzodiazepine. What would be the most appropriate
immediate treatment?
Administer flumazenil
Perform gastric lavage
Administer naloxone
Provide supplemental oxygen
9. Describe the role of N-acetylcysteine in treating Tylenol overdose.
N-acetylcysteine acts as an antidote by replenishing glutathione
levels, which helps to detoxify the harmful metabolites of Tylenol.
N-acetylcysteine neutralizes the Tylenol directly in the bloodstream.
N-acetylcysteine increases the absorption of Tylenol in the liver.
N-acetylcysteine prevents the conversion of Tylenol into its active
form.
10. Discuss why diuretics are contraindicated when a patient is prescribed
lithium.
Diuretics can increase lithium levels in the blood, leading to
toxicity.
Diuretics have no effect on lithium levels.
Diuretics are used to counteract the side effects of lithium.
Diuretics enhance the effectiveness of lithium in treating bipolar
disorder.
, 11. Which of the following is the most important consideration in patients taking
lithium?
1/2 of fluid given in first 8 hours
monitor plasma levels
inuse IV over 60 minutes
must administer with cilastatin
monitor vital signs
prevent with antihistamines
12. Long-term use of steroids can cause all of the following side effects except:
Bruising
Hypotension
Moon face
Osteoporosis
13. Pregabalin (Lyrica), used in the management of diabetes mellitus, will benefit
a patient in which of the following areas?
Peripheral neuropathy
Retinopathy
Nephropathy
Diabetic diarrhea
Gastric autonomic neuropathy
14. A pt arrives at the emergency room immediately following a tylenol
overdose. Which of the following drugs should you prepare to administer?
