root causes of disease
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toxins, allergens, microbes, stress, poor diet
Gut inflammation test
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➢ Assess fecal eosinophil protein X (EPX)
➢ EPX is elevated during inflammatory bowel disease (IBD)
➢ However, EPX is also elevated in atopic dermatitis, intestinal pancreatic
disease, gastroenteritis
➢ Assess fecal calprotectin
➢ Calprotectin is a marker of leukocyte activity
➢ Common in IBS, ulcerative colitis, and Crohn's disease
➢ However, calprotectin is also elevated in bowel cancer and polyps
which of the following are characteristic of an anti-inflammatory diet
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a.Choose whole grain carbohydrates and limit the portion sizes.
b.Include anti-inflammatory herbs and spices such as garlic, turmeric,
rosemary, ginger, oregano, cumin, and cayenne in the diet.
c.Increase vegetable and fruit intake (especially vegetables).
d.Adopt the Okinawan philosophy of "hara hachi bu"- stopping when nearly
8/10 full and paying attention to your hunger and satiety signals.
Discuss the reasons for following a vegetarian diet during a detoxification program.
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- Considering that most biochemical pathways (including phases I, II, and
III) work more effectively in less acidic, more alkaline environments,
vegetarian diets would favor biotransformation reactions
- Additionally, in vegetarian diets, there are sulfur-containing cruciferous
vegetables, which assist in phase I and phase II pathways, fiber-rich fruits,
vegetables, grains, and legumes, which assist in elimination, and
antioxidant-rich sources which quench ROS propagation.
- In general, plant-based foods tend to enhance the activity of phase II
, enzymes, which is NOT harmful. - Amongst all inductions/inhibitions that
can occur, the induction of phase II enzymes is the most favorable.
However, the induction of phase I enzymes ALONE can lead to disease
because a lot of phase I metabolites would emerge and the phase II
enzymes cannot keep up, leading to a build-up of potentially toxic
compounds.
Part of mitochondrial superoxide dismutase (SOD)
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manganese
Maillard reaction products
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formed between amino acids/proteins and a reducing sugar. These Maillard
products provide foods their characteristic browned color. They represent
the previous step in the formation of AGEs (advanced glycation end
products).
lipid peroxidases
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formed by the oxidation of unsaturated fatty acids in the presence of
oxygen; this process is accelerated at high temperatures.
, How are PAMPs recognized?
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• Macrophages and dendritic cells express toll-like receptors (TLRs) on
their surface.
• When TLRs bind to PAMPs, the synthesis of pro-inflammatory cytokines
and NFκB increases.
mediators/perpetuators
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factors, biochemical or psychosocial, that contribute to pathological
changes and dysfunctional responses.
lysozyme
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dissolves cell wall of gram positive bacteria
dehydration leads to
Give this one a try later!
Give this one a try later!
toxins, allergens, microbes, stress, poor diet
Gut inflammation test
,Give this one a try later!
➢ Assess fecal eosinophil protein X (EPX)
➢ EPX is elevated during inflammatory bowel disease (IBD)
➢ However, EPX is also elevated in atopic dermatitis, intestinal pancreatic
disease, gastroenteritis
➢ Assess fecal calprotectin
➢ Calprotectin is a marker of leukocyte activity
➢ Common in IBS, ulcerative colitis, and Crohn's disease
➢ However, calprotectin is also elevated in bowel cancer and polyps
which of the following are characteristic of an anti-inflammatory diet
Give this one a try later!
a.Choose whole grain carbohydrates and limit the portion sizes.
b.Include anti-inflammatory herbs and spices such as garlic, turmeric,
rosemary, ginger, oregano, cumin, and cayenne in the diet.
c.Increase vegetable and fruit intake (especially vegetables).
d.Adopt the Okinawan philosophy of "hara hachi bu"- stopping when nearly
8/10 full and paying attention to your hunger and satiety signals.
Discuss the reasons for following a vegetarian diet during a detoxification program.
Give this one a try later!
- Considering that most biochemical pathways (including phases I, II, and
III) work more effectively in less acidic, more alkaline environments,
vegetarian diets would favor biotransformation reactions
- Additionally, in vegetarian diets, there are sulfur-containing cruciferous
vegetables, which assist in phase I and phase II pathways, fiber-rich fruits,
vegetables, grains, and legumes, which assist in elimination, and
antioxidant-rich sources which quench ROS propagation.
- In general, plant-based foods tend to enhance the activity of phase II
, enzymes, which is NOT harmful. - Amongst all inductions/inhibitions that
can occur, the induction of phase II enzymes is the most favorable.
However, the induction of phase I enzymes ALONE can lead to disease
because a lot of phase I metabolites would emerge and the phase II
enzymes cannot keep up, leading to a build-up of potentially toxic
compounds.
Part of mitochondrial superoxide dismutase (SOD)
Give this one a try later!
manganese
Maillard reaction products
Give this one a try later!
formed between amino acids/proteins and a reducing sugar. These Maillard
products provide foods their characteristic browned color. They represent
the previous step in the formation of AGEs (advanced glycation end
products).
lipid peroxidases
Give this one a try later!
formed by the oxidation of unsaturated fatty acids in the presence of
oxygen; this process is accelerated at high temperatures.
, How are PAMPs recognized?
Give this one a try later!
• Macrophages and dendritic cells express toll-like receptors (TLRs) on
their surface.
• When TLRs bind to PAMPs, the synthesis of pro-inflammatory cytokines
and NFκB increases.
mediators/perpetuators
Give this one a try later!
factors, biochemical or psychosocial, that contribute to pathological
changes and dysfunctional responses.
lysozyme
Give this one a try later!
dissolves cell wall of gram positive bacteria
dehydration leads to
Give this one a try later!
