Questions and Answers Graded A+
1. What are the most common cancers? prostate, breast, lung, colorectal
2. Which cancer is the leading cause of cancer lung
related deaths?
3. What are the 4 treatment modalities for cancer? surgery, radiation, chemo, im-
munotherapy
4. Which treatment modality is most effective in chemotherapy
treating disseminated cancers (leukemia)?
5. Which treatment modality is most effective in surgery
treating and curing solid tumors and debulk-
ing?
6. Cure, prolong survival/maintain quality of life goals of cancer treatment
and/or provide palliative care are the .
7. : ratio of the number of proliferating Cell growth fraction
cells to the total number of cells
8. : the time it takes a tumor mass to double Doubling time
in size.
9. are associated with large growth fraction Small tumors, large tumors
& short doubling time while are associat-
ed with small growth fraction & long doubling
time.
10. Tumor masses are generally cells when 10^9
detected.
11. Drug therapy (chemotherapy) is most effective large growth fraction & short dou-
against cancers with . bling time
, Pharm III: Chemotherapy & General Principles of Cancer Treatment Test
Questions and Answers Graded A+
12. As the tumors enlarge, the rate of growth decreases, increases
while the doubling time .
13. Why is surgery & radiation done before reduce tumor size -> chemo is most
chemotherapy? ettective when tumor is small &
rapidly dividing
14. The of the WBC count is the concen- nadir
tration of WBC's in the peripheral blood after lowest
cytotoxic chemotherapy (usually reached 7-14
days post chemo)
15. ANC is considered neutropenic. < 500 cells/mm^3
16. Adjuvant, neoadjuvant and palliative therapy solid tumors
are treatment options for .
17. : chemotherapy given as a supplement Adjuvant
treatment following surgery and/or radiation to
attack micrometastases.
18. : chemotherapy given prior to surgery to Neoadjuvant
decrease tumor burden.
19. : reduce symptoms, may prolong overall Palliative
survival (OS).
20. Tumor Lysis Syndrome causes an increase in potassium
what: phosphorus
nucleic acids --> uric acid
21. Why is allopurinol started before chemothera- inhibits xanthine oxidase which pre-
py? vents uric acid accumulation