Lecture 1 Clinical
Approach to Anemia &
Microcytic Anemia 2026 |
Study Guide
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success|
Updated 2026 Questions and Answers
100% Verified Exam Prep and Comprehensive
Rationales
Included
, Anemia most common disorder of the blood
1. blood loss the three main causes of anemia
2. destruction of RBC
3. decreased RBC production
Lasthenie de Ferjol Syndrome a very rare psychiatric pathology characterized by severe relapsing anaemia due
to repeated self-induced hemorrhages
• GI or GU tract; obvious or occult main causes of blood loss that can lead to anemia
• Menstrual
• Retroperitoneal
• Nose bleeds, cutting, hematuria
• Lack of iron, B12, folate causes of decreased RBC production that lead to anemia
• Dysfunctional Bone marrow
• Suppressed bone marrow (radiation/chemo)
• Low levels erythropoietin, androgen, thyroid
Bone where does erythropoiesis occur in adults?
Erythropoietin (EPO) -enhances growth and differentiation of two erythroid progenitors to normoblasts
of
increasing maturity.
Reticulocytes Normoblast extrudes its nucleus to form a RBC and is identified as a ___________________
1% Reticulocytes >_____% means bone marrow is working.
Hemolysis The destruction of red blood cells which leads to the release of hemoglobin from
within the red blood cells into the blood plasma
Bi-concave disk shape of RBC
Normochromic Normocytic
Hypochromic
Hyperchromic
Hemoglobin S variant of hemoglobin found in people with sickle cell
Approach to Anemia &
Microcytic Anemia 2026 |
Study Guide
| Graded A+ | Guaranteed
success|
Updated 2026 Questions and Answers
100% Verified Exam Prep and Comprehensive
Rationales
Included
, Anemia most common disorder of the blood
1. blood loss the three main causes of anemia
2. destruction of RBC
3. decreased RBC production
Lasthenie de Ferjol Syndrome a very rare psychiatric pathology characterized by severe relapsing anaemia due
to repeated self-induced hemorrhages
• GI or GU tract; obvious or occult main causes of blood loss that can lead to anemia
• Menstrual
• Retroperitoneal
• Nose bleeds, cutting, hematuria
• Lack of iron, B12, folate causes of decreased RBC production that lead to anemia
• Dysfunctional Bone marrow
• Suppressed bone marrow (radiation/chemo)
• Low levels erythropoietin, androgen, thyroid
Bone where does erythropoiesis occur in adults?
Erythropoietin (EPO) -enhances growth and differentiation of two erythroid progenitors to normoblasts
of
increasing maturity.
Reticulocytes Normoblast extrudes its nucleus to form a RBC and is identified as a ___________________
1% Reticulocytes >_____% means bone marrow is working.
Hemolysis The destruction of red blood cells which leads to the release of hemoglobin from
within the red blood cells into the blood plasma
Bi-concave disk shape of RBC
Normochromic Normocytic
Hypochromic
Hyperchromic
Hemoglobin S variant of hemoglobin found in people with sickle cell
