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HESI A2 Anatomy and Physiology Exam Study Guide – Practice Questions and Answers (Latest Update)

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This document covers the HESI A2 Anatomy and Physiology exam, including practice questions and answers aligned with current exam topics. It focuses on major body systems such as the cardiovascular, respiratory, nervous, digestive, muscular, and skeletal systems, along with basic cellular structure and physiological functions. The material is structured to reflect the HESI A2 exam format and helps students strengthen foundational A&P knowledge required for nursing school entry. It serves as a comprehensive study resource for exam preparation and review.

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HESIA2
Course
HESIA2

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HESI A2 ANATOMY AND
PHYSIOLOGY ACTUAL QESTIONS
AND VERIFIED ASWERS GRADE
A+ 2026.
The specialized junction from which nerve impulses pass from one neuron to the next is
called a _______________________. - answer-Synapse

Which type of bone has a diaphysis and two epiphyses? - answer-Long bone

Which of the following correctly describes the function of luteinizing hormone? -
answer-It stimulates the production of testosterone in males

Which of the following statements is incorrect about estrogen? - answer-It stimulates
ovulation ( This is the luteinizing hormone job)

What is the role of calcium in muscle contraction? - answer-Calcium binds to troponin
and leads to the uncovering of the active site of actin.

Which structure controls the activity of the endocrine system? - answer-Hypothalmus

The left atrium receives blood from the ______. - answer-Pulmonary vein

Which is the most abundant nervous tissue? - answer-Neuroglia

The tibia is _______ to the femur. - answer-Distal

Which of the following organelles would you expect to find an abundance of in
leukocytes? - answer-Lysosomes

A patient with a lower than normal amount of thrombocytes could be at risk of
____________. - answer-extensive bleeding

A sprain occurs when which of the following structures is stretched or torn? - answer-
Ligament

Which of the following glands secrete earwax? - answer-Ceruminous

What is the function of endocrine glands? - answer-They secrete hormones directly into
the blood.

Which of the following occurs when the sympathetic nervous system is stimulated? -
answer-Heart rate increases

Pupils dilate

, Digestion slows down

Which bones form via intramembranous ossification? - answer-The flat bones of the
skull, the mandible, and clavicles

The carpals articulate with the distal ends of which two bones? - answer-Radius and
ulna

Which of the following best describes the function of the mitral valve? - answer-Lets
blood flow from the left atrium to the left ventricle

Which type of connection do ligaments create? - answer-Bone to Bone

Which of the four chambers of the heart has the thickest muscular wall? - answer-Left
ventricle

Which important minerals are stored within the skeletal system? - answer-Calcium and
phosphorous

Which type of tissue is most widely distributed throughout the body? - answer-
Connective tissue

In which of the following reproductive structures does the fertilization of an ovum
occur? - answer-Fallopian tube

Which of the following structures is part of the upper respiratory system? - answer-
Pharynx

Eccrine glands secrete a watery substance onto the surface of the skin to maintain
temperature homeostasis through which process? - answer-Evaporation

What, in addition to adenosine triphosphate, must be present for a muscle to contract?
- answer-Calcium

Mitosis occurs in which layer of the skin? - answer-Stratum germinativum

A patient reveals to you that they were recently involved in a car accident that they
believe resulted in a deviated septum. Which of the following bones may have been
injured in the accident, resulting in the deviated septum? - answer-vomer is a thin,
vertical bone in the nose.

Which of the following describes cellular respiration? - answer-It is an oxidative
catabolic activity

Which structure in the epidermis is responsible for cooling the body to maintain
temperature homeostasis? - answer-Eccrine glands ( produces sweat )

Which system coordinates and regulates processes within the body through the use of
hormones? - answer-Endocrine system

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