Pharmacology HESI & NCLEX Review
2026 | Latest Questions, Answers &
Exam Success Guide
THIS EXAM CONTAINS:
• Comprehensive Pharmacology review notes
• HESI and NCLEX-style practice questions
• Detailed answers
• Dosage calculation practice
• NCLEX test-taking strategies
• Graded A+
,Pharmacology HESI & NCLEX Review 2026 | Latest Questions, & Exam Success
Guide
1. A male client who has been taking a high dose of a nonsteroidal anti-
inflammatory drug (NSAID) comes to the clinic complaining of gastric pain and
blood in his stool. The healthcare provider discontinues the NSAIDs and prescribes
esomeprazole. Which information should the client include in the nurse's teaching
plan?
A. Once pain subsides, NSAID therapy can be continued
B. Resume a diet that consists of milk, cream, and bland foods
C. Notify the healthcare provider of the passage of black stool
D. Call the clinic if diarrhea or headache occur when taking esomeprazole
Correct Answer: C
2. When administering zolpidem to an older client, which computer
documentation indicates that the desired outcome has been achieved?
A. Sleeps soundly through the night
B. Decreased episodes of incontinence
C. Exhibits fewer emotional outburst
D. Improved ability to concentrate
Correct Answer: A
3. A male client with a fungal infection of the toenail reports to the nurse that he
has been applying an over-the-counter triple antibiotic ointment to the infection
daily for two weeks without any improvement. Which action should the nurse
take?
A. Instruct the client to obtain a prescription for oral terbinafine
B. Suggest that the client use the ointment twice a day to be more effective
C. Reassure that the treatment of fungus-infected toenails often takes several
,months
D. Advise the client to obtain a prescription-strength formulation of the ointment
Correct Answer: A
4. A client with a nasogastric tube (NGT) has a prescription for sucralfate. The
liquid form of the medication is not currently available in the pharmacy and
tablets have been delivered to the medication dispensing system. Which action
should the nurse include when administering the medication?
A. Crush the tablet and mix it with water separately from other medications
B. Crush the tablet and mix it with other crushed tablets diluted in water
C. Withhold the medication until a liquid form is available on the nursing unit
D. Crush the tablet and mix it with other liquid medications for administration
Correct Answer: A
Page 2
5. A client with chronic asthma receives a prescription for montelukast, a
leukotriene modifier. Which statement by the client indicates to the nurse that
medication teaching was effective?
A. "I should take this medication only when I am having an asthma attack"
B. "I will take the tablet every evening to control my asthma"
C. "This medication will stop an asthma attack immediately"
D. "I will not need to use my inhalers twice a day when I start this medication"
Correct Answer: B
6. The nurse is planning to administer the antiulcer GI agent sucralfate to a client
with peptic ulcer disease. Which action should the nurse include in this client's
plan of care?
, A. Assess for secondary Candida infection
B. Administer sucralfate once a day, preferably at bedtime
C. Give sucralfate on an empty stomach
D. Monitor for electrolyte imbalance
Correct Answer: C
7. A client with anemia secondary to chronic kidney disease (CKD) started a
prescription for epoetin alfa two months ago. Which client finding best indicates
that the medication is effective?
A. Reports of increased energy levels and decreased fatigue
B. Takes concurrent iron therapy without adverse effects
C. Food diary shows increased consumption of iron-rich foods
D. Hemoglobin level increased to 12 grams/dL (120 mmol/L)
Correct Answer: D
8. The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution,
a strong iodine solution, for a client with hyperthyroidism. How should the nurse
schedule the administration of these medications?
A. Administer iodine one hour before PTU
B. Offer both drugs together with a meal
C. Schedule both medications at bedtime
D. Give parental dose once every 24 hours
Correct Answer: B
Page 3
9. Twenty minutes after the nurse starts a secondary IV infusion of cefepime 2
grams using an infusion pump to deliver the dose in one hour, the client reports
feeling nauseated. Which action should the nurse implement?
2026 | Latest Questions, Answers &
Exam Success Guide
THIS EXAM CONTAINS:
• Comprehensive Pharmacology review notes
• HESI and NCLEX-style practice questions
• Detailed answers
• Dosage calculation practice
• NCLEX test-taking strategies
• Graded A+
,Pharmacology HESI & NCLEX Review 2026 | Latest Questions, & Exam Success
Guide
1. A male client who has been taking a high dose of a nonsteroidal anti-
inflammatory drug (NSAID) comes to the clinic complaining of gastric pain and
blood in his stool. The healthcare provider discontinues the NSAIDs and prescribes
esomeprazole. Which information should the client include in the nurse's teaching
plan?
A. Once pain subsides, NSAID therapy can be continued
B. Resume a diet that consists of milk, cream, and bland foods
C. Notify the healthcare provider of the passage of black stool
D. Call the clinic if diarrhea or headache occur when taking esomeprazole
Correct Answer: C
2. When administering zolpidem to an older client, which computer
documentation indicates that the desired outcome has been achieved?
A. Sleeps soundly through the night
B. Decreased episodes of incontinence
C. Exhibits fewer emotional outburst
D. Improved ability to concentrate
Correct Answer: A
3. A male client with a fungal infection of the toenail reports to the nurse that he
has been applying an over-the-counter triple antibiotic ointment to the infection
daily for two weeks without any improvement. Which action should the nurse
take?
A. Instruct the client to obtain a prescription for oral terbinafine
B. Suggest that the client use the ointment twice a day to be more effective
C. Reassure that the treatment of fungus-infected toenails often takes several
,months
D. Advise the client to obtain a prescription-strength formulation of the ointment
Correct Answer: A
4. A client with a nasogastric tube (NGT) has a prescription for sucralfate. The
liquid form of the medication is not currently available in the pharmacy and
tablets have been delivered to the medication dispensing system. Which action
should the nurse include when administering the medication?
A. Crush the tablet and mix it with water separately from other medications
B. Crush the tablet and mix it with other crushed tablets diluted in water
C. Withhold the medication until a liquid form is available on the nursing unit
D. Crush the tablet and mix it with other liquid medications for administration
Correct Answer: A
Page 2
5. A client with chronic asthma receives a prescription for montelukast, a
leukotriene modifier. Which statement by the client indicates to the nurse that
medication teaching was effective?
A. "I should take this medication only when I am having an asthma attack"
B. "I will take the tablet every evening to control my asthma"
C. "This medication will stop an asthma attack immediately"
D. "I will not need to use my inhalers twice a day when I start this medication"
Correct Answer: B
6. The nurse is planning to administer the antiulcer GI agent sucralfate to a client
with peptic ulcer disease. Which action should the nurse include in this client's
plan of care?
, A. Assess for secondary Candida infection
B. Administer sucralfate once a day, preferably at bedtime
C. Give sucralfate on an empty stomach
D. Monitor for electrolyte imbalance
Correct Answer: C
7. A client with anemia secondary to chronic kidney disease (CKD) started a
prescription for epoetin alfa two months ago. Which client finding best indicates
that the medication is effective?
A. Reports of increased energy levels and decreased fatigue
B. Takes concurrent iron therapy without adverse effects
C. Food diary shows increased consumption of iron-rich foods
D. Hemoglobin level increased to 12 grams/dL (120 mmol/L)
Correct Answer: D
8. The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution,
a strong iodine solution, for a client with hyperthyroidism. How should the nurse
schedule the administration of these medications?
A. Administer iodine one hour before PTU
B. Offer both drugs together with a meal
C. Schedule both medications at bedtime
D. Give parental dose once every 24 hours
Correct Answer: B
Page 3
9. Twenty minutes after the nurse starts a secondary IV infusion of cefepime 2
grams using an infusion pump to deliver the dose in one hour, the client reports
feeling nauseated. Which action should the nurse implement?
