N211 Pharm Unit Test 3 – Full Questions and Answers | Study Guide | 2026
Updated | 100% Correct - Eastwick College.
Chapter 32 – Drugs Used to Treat
Gastroesophageal Reflux and Peptic Ulcer
Disease
1. What is the mechanism of action of antacids?
Answer:
Antacids neutralize stomach acid directly in the stomach.
Rationale:
Antacids provide rapid relief of heartburn and indigestion by reducing gastric acidity.
2. Which antacid is most associated with constipation?
A. Magnesium hydroxide
B. Calcium carbonate
C. Aluminum hydroxide
D. Sodium bicarbonate
Correct Answer:
C. Aluminum hydroxide
Rationale:
Aluminum-containing antacids commonly cause constipation, while magnesium-containing
antacids commonly cause diarrhea.
3. Which side effect is associated with magnesium
hydroxide?
,A. Constipation
B. Diarrhea
C. Hypertension
D. Bradycardia
Correct Answer:
B. Diarrhea
Rationale:
Magnesium antacids increase intestinal motility and frequently cause diarrhea.
4. What is the nursing teaching for antacids?
Answer:
Antacids should be taken 1–3 hours after meals and separated from other medications because
they interfere with medication absorption.
Rationale:
Antacids alter gastric pH and can reduce absorption of many drugs.
5. Which medication is an H₂ receptor blocker?
A. Omeprazole
B. Sucralfate
C. Famotidine
D. Metoclopramide
Correct Answer:
C. Famotidine
Rationale:
Famotidine is an H₂ receptor antagonist that decreases stomach acid secretion by blocking
histamine receptors on parietal cells.
, 6. Which H₂ blocker is associated with gynecomastia and
multiple drug interactions?
A. Nizatidine
B. Famotidine
C. Cimetidine
D. Ranitidine
Correct Answer:
C. Cimetidine
Rationale:
Cimetidine is well known for endocrine effects such as gynecomastia and numerous drug
interactions.
7. What is the mechanism of action of proton pump
inhibitors?
Answer:
PPIs block the proton pump in the stomach, almost completely stopping acid secretion.
Rationale:
They are the most effective acid-reducing medications for GERD and ulcers.
8. Which medication is classified as a proton pump
inhibitor?
A. Omeprazole
B. Famotidine
C. Sucralfate
D. Calcium carbonate
Correct Answer:
Updated | 100% Correct - Eastwick College.
Chapter 32 – Drugs Used to Treat
Gastroesophageal Reflux and Peptic Ulcer
Disease
1. What is the mechanism of action of antacids?
Answer:
Antacids neutralize stomach acid directly in the stomach.
Rationale:
Antacids provide rapid relief of heartburn and indigestion by reducing gastric acidity.
2. Which antacid is most associated with constipation?
A. Magnesium hydroxide
B. Calcium carbonate
C. Aluminum hydroxide
D. Sodium bicarbonate
Correct Answer:
C. Aluminum hydroxide
Rationale:
Aluminum-containing antacids commonly cause constipation, while magnesium-containing
antacids commonly cause diarrhea.
3. Which side effect is associated with magnesium
hydroxide?
,A. Constipation
B. Diarrhea
C. Hypertension
D. Bradycardia
Correct Answer:
B. Diarrhea
Rationale:
Magnesium antacids increase intestinal motility and frequently cause diarrhea.
4. What is the nursing teaching for antacids?
Answer:
Antacids should be taken 1–3 hours after meals and separated from other medications because
they interfere with medication absorption.
Rationale:
Antacids alter gastric pH and can reduce absorption of many drugs.
5. Which medication is an H₂ receptor blocker?
A. Omeprazole
B. Sucralfate
C. Famotidine
D. Metoclopramide
Correct Answer:
C. Famotidine
Rationale:
Famotidine is an H₂ receptor antagonist that decreases stomach acid secretion by blocking
histamine receptors on parietal cells.
, 6. Which H₂ blocker is associated with gynecomastia and
multiple drug interactions?
A. Nizatidine
B. Famotidine
C. Cimetidine
D. Ranitidine
Correct Answer:
C. Cimetidine
Rationale:
Cimetidine is well known for endocrine effects such as gynecomastia and numerous drug
interactions.
7. What is the mechanism of action of proton pump
inhibitors?
Answer:
PPIs block the proton pump in the stomach, almost completely stopping acid secretion.
Rationale:
They are the most effective acid-reducing medications for GERD and ulcers.
8. Which medication is classified as a proton pump
inhibitor?
A. Omeprazole
B. Famotidine
C. Sucralfate
D. Calcium carbonate
Correct Answer:
