PERF 510 -
stoff being tested on
Ch. 1 outline
Physiology = Study of function
Mechanical and biochemical responses to physical activity, stresses and disease
Organizational overview
Organisms→systems→organs→tissues→cellular level→molecular(biochemical)
Essential= C, H, O, N, Ca, P, K, S, Na, Cl, Mg, Fe, and I
Adaptation and Evolution
Abiogenesis → Protocells → Prokaryotic cells → Eukaryotic cells → Today’s Biodiversity
Systemic approach- 11 traditional, a new 12th?
Integumentary, skeletal, muscular, nervous, circulatory, endocrine, respiratory, urinary, digestive,
reproductive, lymphatic, interstitial (extra-cellular) matrix
ICM vs ECM
Perfusion = blood flow = maintaining ECM within limits compatible with life
Life- Metabolism, growth, development, responsiveness, reproduction, etc…
Homeostasis- Maintaining a steady (within “normal” range) internal environment despite changes in the
external environment
Accomplished via feedback systems- receptors → control center → effector organs
Negative Feedback = homeostasis =
response of effector will counteract the
initial deviation
Ex. Temperature, hydration,
glucose levels, CO2, O2, etc…
Positive Feedback = rare since the
response of the effector will enhance the
initial deviation
Ex. Labor, hemorrhagic shock
stoff being tested on
Ch. 1 outline
Physiology = Study of function
Mechanical and biochemical responses to physical activity, stresses and disease
Organizational overview
Organisms→systems→organs→tissues→cellular level→molecular(biochemical)
Essential= C, H, O, N, Ca, P, K, S, Na, Cl, Mg, Fe, and I
Adaptation and Evolution
Abiogenesis → Protocells → Prokaryotic cells → Eukaryotic cells → Today’s Biodiversity
Systemic approach- 11 traditional, a new 12th?
Integumentary, skeletal, muscular, nervous, circulatory, endocrine, respiratory, urinary, digestive,
reproductive, lymphatic, interstitial (extra-cellular) matrix
ICM vs ECM
Perfusion = blood flow = maintaining ECM within limits compatible with life
Life- Metabolism, growth, development, responsiveness, reproduction, etc…
Homeostasis- Maintaining a steady (within “normal” range) internal environment despite changes in the
external environment
Accomplished via feedback systems- receptors → control center → effector organs
Negative Feedback = homeostasis =
response of effector will counteract the
initial deviation
Ex. Temperature, hydration,
glucose levels, CO2, O2, etc…
Positive Feedback = rare since the
response of the effector will enhance the
initial deviation
Ex. Labor, hemorrhagic shock
