AACN PCCN Exam Review:
Multisystem with correct answers
2026
Normal-inflammatory-response---correct-answer-vasodilatation,-increased-microvascular-
permeability,-cellular-activation-and-release-of-mediators,-and-coagulation
Define-sepsis---correct-answer-systemic-response-to-infection,-manifested-by-two-or-more-
conditions-resulting-from-infection-(temp->38C,-HR->90-bpm,-RR->20-bpm,-PaCO2-<32-mmHg,-
WBC->12,-<4)
Define-septic-shock---correct-answer-sepsis-with-hypotension,-despite-adequate-fluid-
resuscitation,-along-with-presence-of-perfusion-abnormalities-including-lactic-acidosis,-oliguria,-
acute-AMS
Risk-factors-for-sepsis---correct-answer-malnutrition,-immunosuppression,-prolonged-antibiotic-
use,-invasive-devices
Define-MODS---correct-answer-multiple-organ-dysfunction,-worsening-progression-of-systemic-
inflammatory-response-(SIRS)-involving-signs-of-organ-dysfunction
, Management-of-sepsis---correct-answer-treat-cause-(antibiotics),-maximize-oxygen,-maximize-CO-
(difficult-bc-pathological-problem-of-SIRS-is-increased-permeability-of-capillary-bed---liberal-fluid-
admin),-decrease-oxygen-demand-(reduce-tachycardia,-tachypnea,-hyperthermia,-pain,-prevent-
shivering,-comfort-measures)
What-is-NOT-an-accurate-measurement-of-adequate-perfusion---correct-answer-BLOOD-
PRESSURE,-adequate-pressure-does-not-always-equal-adequate-perfusion
Symptoms-of-alcohol-withdrawal---correct-answer-insomnia,-tremors,-anxiety,-GI-upset,-HA,-
sweating,-palpitations,-hallucinations,-seizures,-fever,-agitation
How-is-isopropyl-alcohol-intoxication-distinguished-from-other-types-of-alcohol-intoxication---
correct-answer-presence-of-ketoacids-in-urine-and-serum
Which-imbalance-is-seen-in-methanol-intoxication-and-relieved-by-hyperventilation---correct-
answer-metabolic-acidosis-(decreased-bicarbonate-level)
Which-alcohol-intoxication-affects-renal-tubular-degeneration---correct-answer-ethylene-glycol-
intoxication
Which-vitamins-are-most-important-in-alcohol-withdrawal---correct-answer-thiamine,-folate-
(banana-bag-of-B-vitamins)
Signs-and-symptoms-applicable-to-majority-of-drug-overdose---correct-answer-decreased-LOC,-
behavioral-changes,-respiratory-depression
Antidote-for-acetaminophen---correct-answer-N-acetylcysteine
Antidote-for-opiates---correct-answer-naloxone
Multisystem with correct answers
2026
Normal-inflammatory-response---correct-answer-vasodilatation,-increased-microvascular-
permeability,-cellular-activation-and-release-of-mediators,-and-coagulation
Define-sepsis---correct-answer-systemic-response-to-infection,-manifested-by-two-or-more-
conditions-resulting-from-infection-(temp->38C,-HR->90-bpm,-RR->20-bpm,-PaCO2-<32-mmHg,-
WBC->12,-<4)
Define-septic-shock---correct-answer-sepsis-with-hypotension,-despite-adequate-fluid-
resuscitation,-along-with-presence-of-perfusion-abnormalities-including-lactic-acidosis,-oliguria,-
acute-AMS
Risk-factors-for-sepsis---correct-answer-malnutrition,-immunosuppression,-prolonged-antibiotic-
use,-invasive-devices
Define-MODS---correct-answer-multiple-organ-dysfunction,-worsening-progression-of-systemic-
inflammatory-response-(SIRS)-involving-signs-of-organ-dysfunction
, Management-of-sepsis---correct-answer-treat-cause-(antibiotics),-maximize-oxygen,-maximize-CO-
(difficult-bc-pathological-problem-of-SIRS-is-increased-permeability-of-capillary-bed---liberal-fluid-
admin),-decrease-oxygen-demand-(reduce-tachycardia,-tachypnea,-hyperthermia,-pain,-prevent-
shivering,-comfort-measures)
What-is-NOT-an-accurate-measurement-of-adequate-perfusion---correct-answer-BLOOD-
PRESSURE,-adequate-pressure-does-not-always-equal-adequate-perfusion
Symptoms-of-alcohol-withdrawal---correct-answer-insomnia,-tremors,-anxiety,-GI-upset,-HA,-
sweating,-palpitations,-hallucinations,-seizures,-fever,-agitation
How-is-isopropyl-alcohol-intoxication-distinguished-from-other-types-of-alcohol-intoxication---
correct-answer-presence-of-ketoacids-in-urine-and-serum
Which-imbalance-is-seen-in-methanol-intoxication-and-relieved-by-hyperventilation---correct-
answer-metabolic-acidosis-(decreased-bicarbonate-level)
Which-alcohol-intoxication-affects-renal-tubular-degeneration---correct-answer-ethylene-glycol-
intoxication
Which-vitamins-are-most-important-in-alcohol-withdrawal---correct-answer-thiamine,-folate-
(banana-bag-of-B-vitamins)
Signs-and-symptoms-applicable-to-majority-of-drug-overdose---correct-answer-decreased-LOC,-
behavioral-changes,-respiratory-depression
Antidote-for-acetaminophen---correct-answer-N-acetylcysteine
Antidote-for-opiates---correct-answer-naloxone
