ATI Pharmacology CMS NGN Practice
Questions (With Answers & Rationales)
1. Anticoagulants (Warfarin)
A nurse is teaching a client prescribed warfarin for atrial fibrillation. Which statement indicates
understanding?
A. “I will increase green leafy vegetables daily.”
B. “I will take aspirin for headaches.”
C. “I will have my INR checked regularly.”
D. “I will stop medication once symptoms improve.”
Correct Answer: C
Rationale: Warfarin requires monitoring of INR (goal usually 2–3). Vitamin K intake should remain
consistent, not increased. Aspirin increases bleeding risk.
2. Insulin Administration
A client receives insulin glargine and lispro. What should the nurse do?
A. Mix both insulins in one syringe
B. Give lispro before meals
C. Give glargine IV
D. Shake both insulin types before use
Correct Answer: B
Rationale: Lispro is rapid-acting and given before meals. Glargine is long-acting and never mixed or
shaken.
3. NGN Clinical Judgment: Digoxin Toxicity
A client taking digoxin reports nausea, vomiting, and seeing yellow halos.
What is the priority action?
A. Give next dose as scheduled
B. Hold medication and notify provider
,C. Increase potassium intake
D. Encourage fluid restriction
Correct Answer: B
Rationale: These are signs of digoxin toxicity. Medication must be held immediately.
4. Antibiotics
A nurse is administering gentamicin. Which lab should be monitored?
A. ALT
B. Creatinine
C. Troponin
D. INR
Correct Answer: B
Rationale: Gentamicin is nephrotoxic → monitor kidney function (creatinine, BUN).
5. NGN Prioritization (Respiratory)
A client with asthma is wheezing and using accessory muscles.
What is the priority medication?
A. Oral prednisone
B. Albuterol inhaler
C. Montelukast
D. Theophylline
Correct Answer: B
Rationale: Albuterol is a fast-acting bronchodilator for acute bronchospasm.
6. Electrolytes & Diuretics
A client on furosemide is at risk for which imbalance?
A. Hyperkalemia
B. Hypokalemia
C. Hypernatremia
D. Hypocalcemia
Correct Answer: B
Rationale: Loop diuretics waste potassium → hypokalemia.
,7. NGN SATA (Select all that apply)
Which are teaching points for ACE inhibitors (lisinopril)?
✔ Monitor blood pressure
✔ Report dry cough
✔ Avoid potassium supplements
✔ Take with grapefruit juice
Correct Answers: A, B, C
Rationale: ACE inhibitors can cause hypotension, dry cough, and hyperkalemia. Grapefruit juice is not
required avoidance (more relevant to statins).
8. Opioids
Which is a priority assessment before giving morphine?
A. Respiratory rate
B. Blood glucose
C. Temperature
D. Reflexes
Correct Answer: A
Rationale: Opioids depress respiration → check RR first.
9. NGN Delegation
Which task can be delegated to a UAP?
A. Assess pain level
B. Teach insulin injection
C. Assist with ambulation
D. Evaluate lab results
Correct Answer: C
Rationale: UAP can assist with ADLs and ambulation but not assessment or teaching.
10. Cardiac Drugs
A client is on propranolol. What should the nurse monitor?
, A. Heart rate
B. Liver enzymes only
C. Blood glucose only
D. Oxygen saturation only
Correct Answer: A
Rationale: Beta blockers reduce heart rate and blood pressure.
Here is a FULL ATI Pharmacology CMS NGN-style Mock Exam (80 Questions) with
correct answers + concise rationales.
This is designed to closely match ATI difficulty, NGN clinical judgment style, and
pharmacology content distribution.
ATI PHARMACOLOGY CMS NGN MOCK
EXAM (80 QUESTIONS)
1. Warfarin Teaching
Which statement indicates correct understanding?
A. “I will take aspirin for pain.”
B. “I will report unusual bruising.”
C. “I will double my dose if I miss one.”
D. “I will stop eating all green vegetables.”
Answer: B
Rationale: Bleeding is a priority risk. Aspirin increases bleeding risk; vitamin K intake should
be consistent.
2. Insulin Lispro
When should lispro be given?
A. At bedtime
B. 30 minutes after meals
Questions (With Answers & Rationales)
1. Anticoagulants (Warfarin)
A nurse is teaching a client prescribed warfarin for atrial fibrillation. Which statement indicates
understanding?
A. “I will increase green leafy vegetables daily.”
B. “I will take aspirin for headaches.”
C. “I will have my INR checked regularly.”
D. “I will stop medication once symptoms improve.”
Correct Answer: C
Rationale: Warfarin requires monitoring of INR (goal usually 2–3). Vitamin K intake should remain
consistent, not increased. Aspirin increases bleeding risk.
2. Insulin Administration
A client receives insulin glargine and lispro. What should the nurse do?
A. Mix both insulins in one syringe
B. Give lispro before meals
C. Give glargine IV
D. Shake both insulin types before use
Correct Answer: B
Rationale: Lispro is rapid-acting and given before meals. Glargine is long-acting and never mixed or
shaken.
3. NGN Clinical Judgment: Digoxin Toxicity
A client taking digoxin reports nausea, vomiting, and seeing yellow halos.
What is the priority action?
A. Give next dose as scheduled
B. Hold medication and notify provider
,C. Increase potassium intake
D. Encourage fluid restriction
Correct Answer: B
Rationale: These are signs of digoxin toxicity. Medication must be held immediately.
4. Antibiotics
A nurse is administering gentamicin. Which lab should be monitored?
A. ALT
B. Creatinine
C. Troponin
D. INR
Correct Answer: B
Rationale: Gentamicin is nephrotoxic → monitor kidney function (creatinine, BUN).
5. NGN Prioritization (Respiratory)
A client with asthma is wheezing and using accessory muscles.
What is the priority medication?
A. Oral prednisone
B. Albuterol inhaler
C. Montelukast
D. Theophylline
Correct Answer: B
Rationale: Albuterol is a fast-acting bronchodilator for acute bronchospasm.
6. Electrolytes & Diuretics
A client on furosemide is at risk for which imbalance?
A. Hyperkalemia
B. Hypokalemia
C. Hypernatremia
D. Hypocalcemia
Correct Answer: B
Rationale: Loop diuretics waste potassium → hypokalemia.
,7. NGN SATA (Select all that apply)
Which are teaching points for ACE inhibitors (lisinopril)?
✔ Monitor blood pressure
✔ Report dry cough
✔ Avoid potassium supplements
✔ Take with grapefruit juice
Correct Answers: A, B, C
Rationale: ACE inhibitors can cause hypotension, dry cough, and hyperkalemia. Grapefruit juice is not
required avoidance (more relevant to statins).
8. Opioids
Which is a priority assessment before giving morphine?
A. Respiratory rate
B. Blood glucose
C. Temperature
D. Reflexes
Correct Answer: A
Rationale: Opioids depress respiration → check RR first.
9. NGN Delegation
Which task can be delegated to a UAP?
A. Assess pain level
B. Teach insulin injection
C. Assist with ambulation
D. Evaluate lab results
Correct Answer: C
Rationale: UAP can assist with ADLs and ambulation but not assessment or teaching.
10. Cardiac Drugs
A client is on propranolol. What should the nurse monitor?
, A. Heart rate
B. Liver enzymes only
C. Blood glucose only
D. Oxygen saturation only
Correct Answer: A
Rationale: Beta blockers reduce heart rate and blood pressure.
Here is a FULL ATI Pharmacology CMS NGN-style Mock Exam (80 Questions) with
correct answers + concise rationales.
This is designed to closely match ATI difficulty, NGN clinical judgment style, and
pharmacology content distribution.
ATI PHARMACOLOGY CMS NGN MOCK
EXAM (80 QUESTIONS)
1. Warfarin Teaching
Which statement indicates correct understanding?
A. “I will take aspirin for pain.”
B. “I will report unusual bruising.”
C. “I will double my dose if I miss one.”
D. “I will stop eating all green vegetables.”
Answer: B
Rationale: Bleeding is a priority risk. Aspirin increases bleeding risk; vitamin K intake should
be consistent.
2. Insulin Lispro
When should lispro be given?
A. At bedtime
B. 30 minutes after meals
