NURS 663 Exam 1 Questions and
Answers
Bipolar one disorder DSM five criteria -
Manic episode: 1+ week of a colon elevated, expansive or irritable mood and increase
energy. 3+ symptoms from B: distractibility, indiscretion, irresponsible, grandiosity, flight
of ideas, activity(Increase goal-orient), decreased need for sleep, talkativeness or
pressured speech.
Bipolar two DSM five criteria -
Hypo mania and major depressive disorder: hypo mania same as mania with
decreased severity and duration and no functional impairment for episode of four or
more days and no psychosis
Mixed episodes (bipolar) -
Manic and depressive symptoms time by side usually with comorbid substance abuse
increased risk of suicide and psychosis
rapid cycling -
Four or more cycles per year no greater than a week well period
Cyclothymia DSM-V Criteria -
Two or more years of mood cycling with dysthymia and hypo mania decreased
intensity than bipolar disorder meets criteria for hypo mania but does not meet criteria
for major depressive disorder
Dysthymia DSM five criteria -
HE'S 2 SAD depressive symptoms lasting two or more years that is subsydromal
characterized by hopelessness decreased energy, decrease self-esteem for two years,
abnormal sleep, abnormal appetite impaired decision-making.
MAOÍ Mechanism of action generally -
Catalyzes the deamination of monoamines intracellularly and MAO transport
Reuptake extracellular monoamines
MAO-A Mechanism of action -
MAO-A Oxidizes serotonin norepinephrine and epinephrine
MAO-B Mechanism of action -
Oxidizes phenylalanine
MAO-A and MAO-B mechanism of action -
Oxidizes dopamine non-preferentially
, MAOs Neumonic -2 -
Date with Tyra banks with wine and cheese in Maui— can cause hypertensive crisis
related to tyramine from aged food.
MAWIs= my arms weight increased= effective for atypical depression
MAOs adverse effects-6 -
Hypertensive crisis, diet restriction, avoid meds, five week after Prozac, two week
after other antidepressants, no other medications for two weeks after discontinuing
MAOs diet restriction-4 compounds -
Tyrosine, high tyramine, tryptophan, phenylalanine
Tyrosine foods-10 -
Aged cheese, aged wine, fava or broad bean pods, sauerkraut, soy sauce, tap or draft
beer, overripe fruit, cured meat, spoiled food
MAOs drugs to avoid- 6 -
Antidepressants, Dextromethorphan, stimulants, sympathomimetics, meperidine,
disulfiram
MAOs side effects 11 -
Increased weight, drowsy, dizzy, orthostatic hypotension, tremor, headache, dry
mouth, constipation, change in sexual drive, peripheral Edema, sweating
Tricyclic mechanism of action -
Inhibit 5HT2, norepinephrine, dopamine and reuptake slows. Amino group interferes
with ASP - 98 in HSERT. Causing down regulation of receptors.
Tricyclic side effects -
Anticholinergic effects (dry mouth, blurred vision, constipation, urine retention,
impotence). Histamine effects (sedation, increased weight). Adrenergic alpha receptor
(postural hypotension). Direct membrane effects (decrease seizure threshold and
arrhythmias). 5HT2 receptor (increase weight and decrease anxiety).
Amitriptyline dosing/Class -
Start at 25 to 50 mg per day, titrate 25 to 50 mg per day per week, Max dose is 300
mg per day/TCA
Names of tricyclics 10 -
Amitriptyline, nortriptyline, clomipramine, imipramine, protriptyline, doxepin,
amoxapine, desipramine, mapratiline, tripramine
Tricyclics are useful-2 -
Pain, migraine
Answers
Bipolar one disorder DSM five criteria -
Manic episode: 1+ week of a colon elevated, expansive or irritable mood and increase
energy. 3+ symptoms from B: distractibility, indiscretion, irresponsible, grandiosity, flight
of ideas, activity(Increase goal-orient), decreased need for sleep, talkativeness or
pressured speech.
Bipolar two DSM five criteria -
Hypo mania and major depressive disorder: hypo mania same as mania with
decreased severity and duration and no functional impairment for episode of four or
more days and no psychosis
Mixed episodes (bipolar) -
Manic and depressive symptoms time by side usually with comorbid substance abuse
increased risk of suicide and psychosis
rapid cycling -
Four or more cycles per year no greater than a week well period
Cyclothymia DSM-V Criteria -
Two or more years of mood cycling with dysthymia and hypo mania decreased
intensity than bipolar disorder meets criteria for hypo mania but does not meet criteria
for major depressive disorder
Dysthymia DSM five criteria -
HE'S 2 SAD depressive symptoms lasting two or more years that is subsydromal
characterized by hopelessness decreased energy, decrease self-esteem for two years,
abnormal sleep, abnormal appetite impaired decision-making.
MAOÍ Mechanism of action generally -
Catalyzes the deamination of monoamines intracellularly and MAO transport
Reuptake extracellular monoamines
MAO-A Mechanism of action -
MAO-A Oxidizes serotonin norepinephrine and epinephrine
MAO-B Mechanism of action -
Oxidizes phenylalanine
MAO-A and MAO-B mechanism of action -
Oxidizes dopamine non-preferentially
, MAOs Neumonic -2 -
Date with Tyra banks with wine and cheese in Maui— can cause hypertensive crisis
related to tyramine from aged food.
MAWIs= my arms weight increased= effective for atypical depression
MAOs adverse effects-6 -
Hypertensive crisis, diet restriction, avoid meds, five week after Prozac, two week
after other antidepressants, no other medications for two weeks after discontinuing
MAOs diet restriction-4 compounds -
Tyrosine, high tyramine, tryptophan, phenylalanine
Tyrosine foods-10 -
Aged cheese, aged wine, fava or broad bean pods, sauerkraut, soy sauce, tap or draft
beer, overripe fruit, cured meat, spoiled food
MAOs drugs to avoid- 6 -
Antidepressants, Dextromethorphan, stimulants, sympathomimetics, meperidine,
disulfiram
MAOs side effects 11 -
Increased weight, drowsy, dizzy, orthostatic hypotension, tremor, headache, dry
mouth, constipation, change in sexual drive, peripheral Edema, sweating
Tricyclic mechanism of action -
Inhibit 5HT2, norepinephrine, dopamine and reuptake slows. Amino group interferes
with ASP - 98 in HSERT. Causing down regulation of receptors.
Tricyclic side effects -
Anticholinergic effects (dry mouth, blurred vision, constipation, urine retention,
impotence). Histamine effects (sedation, increased weight). Adrenergic alpha receptor
(postural hypotension). Direct membrane effects (decrease seizure threshold and
arrhythmias). 5HT2 receptor (increase weight and decrease anxiety).
Amitriptyline dosing/Class -
Start at 25 to 50 mg per day, titrate 25 to 50 mg per day per week, Max dose is 300
mg per day/TCA
Names of tricyclics 10 -
Amitriptyline, nortriptyline, clomipramine, imipramine, protriptyline, doxepin,
amoxapine, desipramine, mapratiline, tripramine
Tricyclics are useful-2 -
Pain, migraine
