Evolve Pharmacology
HESI Practice Questions
& Study Guide with
Answers and Rationales |
Nursing Pharm
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Updated 2026 Questions and Answers
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, 4/24/26, 7:06 PM Evolve Pharmacology hesi practice Flashcards | Quizlet
A client who has been taking phenazopyridine (Pyridium) C) Have you had any relief from urinary pain, burning, or urgency?
for symptoms of urethritis and cystitis comes to the clinic Feedback:
because her urine is reddish-orange. Which question Phenazopyridine, an over-the-counter urinary analgesic, acts on the mucosa of the
should the practical nurse ask to determine if the urinary tract to relieve urinary pain, burning, itching, or urgency (C) associated with
medication has been effective? urethritis and cystitis. Although determining if the client is forcing fluids (A),
A) How much water have you been drinking each day? experiencing staining from Pyridium's side effect (B), or having signs of a urinary
B) Does the urine color stain your toilet bowl or infection (D) are worthwhile assessments, the therapeutic response of Pyridium is
undergarments? related to urinary discomforts only.
C) Have you had any relief from urinary pain, burning, or
urgency?
D) Did your urine appear cloudy or have a foul odor on
voiding?
A male client who has been receiving an antineoplastic D) Shave with an electric razor.
drug has developed thrombocytopenia. What instructions Feedback:
should the practical nurse (PN) reinforce? Thrombocytopenia is a common side effect of bone marrow depression caused by
A) Use suppository form of drugs. several antineoplastic agents. The client is experiencing a low platelet count and
B) Avoid large public gatherings. should use an electric razor (D) to reduce his risk of bleeding. (A, B, and C) are not
C) Rise slowly when standing up. indicated for a client who needs to implement thrombocytopenia precautions.
D) Shave with an electric razor.
The practical nurse (PN) is caring for a client who has B) Weight gain.
been taking prednisone (Deltasone) daily for a year. Which Feedback:
adverse effect should the PN document in the client's Long term use of prednisone causes fluid retention and redistribution of fat
record? deposition. Weight gain (B) and moon face reflect adverse effects of long-term
A) Photosensitvity. prednisone use and should be documented. (A, C, and D) do not occur with
B) Weight gain. treatment using prednisone.
C) Loss of hair.
D) Pale skin color.
A female client with recurring headaches tells the practical B) Hepatic enzymes.
nurse (PN) that she has been taking at least 4 grams of Feedback:
acetaminophen a day. Which laboratory studies should the Liver toxicity can occur when doses of acetaminophen exceed 4 grams a day,
PN review for this client? resulting in an elevation in hepatic enzyme values (B). (A, C, and D) do not reveal
A) Creatinine clearance. findings related to acetaminophen toxicity.
B) Hepatic enzymes.
C) Coagulation values.
D) Arterial blood gases.
A client receives a prescription for an oral opioid analgesic A) Constipation.
for post-operative pain. Which adverse effect should the Feedback:
practical nurse (PN) monitor for with the client? Opioid analgesics slow peristalsis, which leads to constipation (A), a common side
A) Constipation. effect of opiates. (B, C, and D) are not associated with opioid analgesics.
B) Photosensitivity.
C) Decreased heart rate.
D) Frequent urination.
Which action should the practical nurse implement when D) Place the medication between the upper molar teeth and cheek.
administering a buccal medication? Feedback:
A) Encourage the client to swallow. Buccal medications are placed between the upper molar teeth and the cheek (D) for
B) Administer water with medication. absorption by the capillaries of the oral mucosa. The client should be cautioned
C) Ensure the medication is positioned under the tongue. against swallowing, not (A). Buccal medications are not administered with water (B).
D) Place the medication between the upper molar teeth (C) describes sublingual administration.
and cheek.
What assessment is most important for the practical nurse C) Understanding of diet modification.
(PN) to obtain prior to initiating medication therapy with Feedback:
phenelzine (Nardil) for a client with depression? To prevent a potentially lethal hypertensive crisis, a tyramine-free diet should be
A) Activity level. maintained during antidepressant therapy with Nardil, a monoamine oxidase
B) Mood and affect. inhibitor (MAOI). It is most important to determine if the client understands diet
C) Understanding of diet modification. modification (C) before Nardil is initiated to prevent consumption of foods that
D) The client's support system. interact with Nardil. Although a client's activity level (A) and mood and affect (B)
should be monitored during antidepressant therapy, it is most important that the
client understand diet modifications. The client's support system (D) and network of
family and friends is important, but the client should understand the responsibility of
dietary compliance with the medication regimen.
https://quizlet.com/87170320/evolve-pharmacology-hesi-practice-flash-cards/ 1/9
HESI Practice Questions
& Study Guide with
Answers and Rationales |
Nursing Pharm
Comprehensive Review |
Graded A+ | Guaranteed
success
Updated 2026 Questions and Answers
100% Verified Exam Prep and Comprehensive
Rationales
Included
, 4/24/26, 7:06 PM Evolve Pharmacology hesi practice Flashcards | Quizlet
A client who has been taking phenazopyridine (Pyridium) C) Have you had any relief from urinary pain, burning, or urgency?
for symptoms of urethritis and cystitis comes to the clinic Feedback:
because her urine is reddish-orange. Which question Phenazopyridine, an over-the-counter urinary analgesic, acts on the mucosa of the
should the practical nurse ask to determine if the urinary tract to relieve urinary pain, burning, itching, or urgency (C) associated with
medication has been effective? urethritis and cystitis. Although determining if the client is forcing fluids (A),
A) How much water have you been drinking each day? experiencing staining from Pyridium's side effect (B), or having signs of a urinary
B) Does the urine color stain your toilet bowl or infection (D) are worthwhile assessments, the therapeutic response of Pyridium is
undergarments? related to urinary discomforts only.
C) Have you had any relief from urinary pain, burning, or
urgency?
D) Did your urine appear cloudy or have a foul odor on
voiding?
A male client who has been receiving an antineoplastic D) Shave with an electric razor.
drug has developed thrombocytopenia. What instructions Feedback:
should the practical nurse (PN) reinforce? Thrombocytopenia is a common side effect of bone marrow depression caused by
A) Use suppository form of drugs. several antineoplastic agents. The client is experiencing a low platelet count and
B) Avoid large public gatherings. should use an electric razor (D) to reduce his risk of bleeding. (A, B, and C) are not
C) Rise slowly when standing up. indicated for a client who needs to implement thrombocytopenia precautions.
D) Shave with an electric razor.
The practical nurse (PN) is caring for a client who has B) Weight gain.
been taking prednisone (Deltasone) daily for a year. Which Feedback:
adverse effect should the PN document in the client's Long term use of prednisone causes fluid retention and redistribution of fat
record? deposition. Weight gain (B) and moon face reflect adverse effects of long-term
A) Photosensitvity. prednisone use and should be documented. (A, C, and D) do not occur with
B) Weight gain. treatment using prednisone.
C) Loss of hair.
D) Pale skin color.
A female client with recurring headaches tells the practical B) Hepatic enzymes.
nurse (PN) that she has been taking at least 4 grams of Feedback:
acetaminophen a day. Which laboratory studies should the Liver toxicity can occur when doses of acetaminophen exceed 4 grams a day,
PN review for this client? resulting in an elevation in hepatic enzyme values (B). (A, C, and D) do not reveal
A) Creatinine clearance. findings related to acetaminophen toxicity.
B) Hepatic enzymes.
C) Coagulation values.
D) Arterial blood gases.
A client receives a prescription for an oral opioid analgesic A) Constipation.
for post-operative pain. Which adverse effect should the Feedback:
practical nurse (PN) monitor for with the client? Opioid analgesics slow peristalsis, which leads to constipation (A), a common side
A) Constipation. effect of opiates. (B, C, and D) are not associated with opioid analgesics.
B) Photosensitivity.
C) Decreased heart rate.
D) Frequent urination.
Which action should the practical nurse implement when D) Place the medication between the upper molar teeth and cheek.
administering a buccal medication? Feedback:
A) Encourage the client to swallow. Buccal medications are placed between the upper molar teeth and the cheek (D) for
B) Administer water with medication. absorption by the capillaries of the oral mucosa. The client should be cautioned
C) Ensure the medication is positioned under the tongue. against swallowing, not (A). Buccal medications are not administered with water (B).
D) Place the medication between the upper molar teeth (C) describes sublingual administration.
and cheek.
What assessment is most important for the practical nurse C) Understanding of diet modification.
(PN) to obtain prior to initiating medication therapy with Feedback:
phenelzine (Nardil) for a client with depression? To prevent a potentially lethal hypertensive crisis, a tyramine-free diet should be
A) Activity level. maintained during antidepressant therapy with Nardil, a monoamine oxidase
B) Mood and affect. inhibitor (MAOI). It is most important to determine if the client understands diet
C) Understanding of diet modification. modification (C) before Nardil is initiated to prevent consumption of foods that
D) The client's support system. interact with Nardil. Although a client's activity level (A) and mood and affect (B)
should be monitored during antidepressant therapy, it is most important that the
client understand diet modifications. The client's support system (D) and network of
family and friends is important, but the client should understand the responsibility of
dietary compliance with the medication regimen.
https://quizlet.com/87170320/evolve-pharmacology-hesi-practice-flash-cards/ 1/9
