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NR 507 ADVANCED PATHOPHYSIOLOGY MIDTERM TEST|QUESTIONS AND VERIFIED ANSWERS|LATEST 2026 UPDATE|GRADED A+

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NR 507 ADVANCED PATHOPHYSIOLOGY MIDTERM TEST|QUESTIONS AND VERIFIED ANSWERS|LATEST 2026 UPDATE|GRADED A+

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Acute renal failure - ANSWERReversible

Determining prognosis- kidneys respond to diuretic with good output; this indicates that kidneys are
functioning well



Acute Pyelonephritis - ANSWERDiagnosing by clinical symptoms alone can be difficult; can be similar to
cystitis



Diagnosis established by:

-Urine culture

-Urinalysis (WBC casts indicates pyelonephritis, but may not always be present)

-Signs/Symptoms

-Complicated pyelonephritis requires blood cultures and urinary tract imaging



Renal Calculi (Renal Stones) - ANSWERGoals of Treatment:

Manage acute pain

Promote passage of stone

Reduce size of stone

Prevent new stone formation



Chronic Renal Failure - ANSWERChronic Kidney Disease (CKD) is a progressive loss of renal function
associated with systemic disease such as hypertension, diabetes mellitus (most significant risk factor),
systemic lupus erythematosus or intrinsic kidney disease

CKD stage is determined by estimates of GFR and albuminuria

, Who is a candidate for dialysis? - ANSWEREnd-stage renal disease (ESRD) is the final stage of CKD with
the number one cause being diabetes mellitus combined with hypertension. At this point, the patient is
completely dependent on dialysis to survive.

CKD is classified into five stages and is based on the patient's GFR rather than symptoms.



Patients will need dialysis when the following symptoms are present:

--Metabolic acidosis.

--Hyperkalemia: Hyperkalemia in the presence of EKG changes (peaked T-waves) is an indication for
dialysis. --Hyperkalemia by itself is not an indication for dialysis.

--Drug toxicity: Drug toxicity due to the following drugs is an indication for dialysis and include
salicylates, Lithium, Isopropanol, Methanol and Ethylene glycol).

--Fluid volume overload that is not responsive to diuretics.

--Uremic symptoms due to nitrogenous wastes in the blood stream.



Stage I CKD - ANSWERThere is kidney damage with normal or elevated GFR

90-120



Stage II CKD - ANSWERThere is kidney damage with mild decrease in GFR

60-89



Stage III CKD - ANSWERThere is a moderate decrease in GFR

30-59



Stage IV CKD - ANSWERThere is a severe decrease in GFR

15-29



Stage V CKD - ANSWERKidney failure- End-stage renal disease

<15 (dialysis) Once Stage IV is reached, progression to Stage V is inevitable as well as dialysis or kidney
transplant

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