NUR 6111 ADVANCED PRACTICE
NURSING I EXAM 2 (2026-2027)
COMPLETE PRACTICE QUESTIONS,
ANSWERS, AND RATIONALES
Practice Questions (1–200)
1. A patient with heart failure is prescribed an ACE inhibitor. What is the primary mechanism of
action?
A. Increase heart rate
B. Block conversion of angiotensin I to II
C. Increase sodium retention
D. Stimulate aldosterone
Answer: B
Rationale: ACE inhibitors reduce angiotensin II, leading to vasodilation and decreased
preload/afterload.
2. Which lab value is most indicative of worsening heart failure?
A. BNP elevation
B. Low potassium
C. High calcium
D. Low glucose
Answer: A
Rationale: BNP is released with ventricular stretch and correlates with HF severity.
3. What is first-line treatment for acute asthma exacerbation?
A. Inhaled corticosteroids
B. Short-acting beta-agonists
C. Long-acting beta-agonists
D. Oral antibiotics
Answer: B
Rationale: SABAs provide rapid bronchodilation.
4. A hallmark of Type 2 Diabetes pathophysiology is:
A. Absolute insulin deficiency
B. Autoimmune destruction
, C. Insulin resistance
D. Hypoglycemia
Answer: C
Rationale: T2DM involves insulin resistance with relative insulin deficiency.
5. Which medication class reduces mortality in heart failure?
A. NSAIDs
B. ACE inhibitors
C. Calcium supplements
D. Antacids
Answer: B
Rationale: ACE inhibitors improve survival in HF patients.
6. What is the most common cause of GERD?
A. Increased gastric acid only
B. Lower esophageal sphincter dysfunction
C. Infection
D. Cancer
Answer: B
Rationale: LES dysfunction allows acid reflux.
7. Which electrolyte imbalance is common with loop diuretics?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hyponatremia only
Answer: B
Rationale: Loop diuretics increase potassium loss.
8. COPD is primarily characterized by:
A. Reversible airflow limitation
B. Permanent airflow limitation
C. Acute infection
D. Fluid overload
Answer: B
Rationale: COPD causes irreversible airflow limitation.
9. Which hormone is elevated in hyperthyroidism?
A. TSH
NURSING I EXAM 2 (2026-2027)
COMPLETE PRACTICE QUESTIONS,
ANSWERS, AND RATIONALES
Practice Questions (1–200)
1. A patient with heart failure is prescribed an ACE inhibitor. What is the primary mechanism of
action?
A. Increase heart rate
B. Block conversion of angiotensin I to II
C. Increase sodium retention
D. Stimulate aldosterone
Answer: B
Rationale: ACE inhibitors reduce angiotensin II, leading to vasodilation and decreased
preload/afterload.
2. Which lab value is most indicative of worsening heart failure?
A. BNP elevation
B. Low potassium
C. High calcium
D. Low glucose
Answer: A
Rationale: BNP is released with ventricular stretch and correlates with HF severity.
3. What is first-line treatment for acute asthma exacerbation?
A. Inhaled corticosteroids
B. Short-acting beta-agonists
C. Long-acting beta-agonists
D. Oral antibiotics
Answer: B
Rationale: SABAs provide rapid bronchodilation.
4. A hallmark of Type 2 Diabetes pathophysiology is:
A. Absolute insulin deficiency
B. Autoimmune destruction
, C. Insulin resistance
D. Hypoglycemia
Answer: C
Rationale: T2DM involves insulin resistance with relative insulin deficiency.
5. Which medication class reduces mortality in heart failure?
A. NSAIDs
B. ACE inhibitors
C. Calcium supplements
D. Antacids
Answer: B
Rationale: ACE inhibitors improve survival in HF patients.
6. What is the most common cause of GERD?
A. Increased gastric acid only
B. Lower esophageal sphincter dysfunction
C. Infection
D. Cancer
Answer: B
Rationale: LES dysfunction allows acid reflux.
7. Which electrolyte imbalance is common with loop diuretics?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hyponatremia only
Answer: B
Rationale: Loop diuretics increase potassium loss.
8. COPD is primarily characterized by:
A. Reversible airflow limitation
B. Permanent airflow limitation
C. Acute infection
D. Fluid overload
Answer: B
Rationale: COPD causes irreversible airflow limitation.
9. Which hormone is elevated in hyperthyroidism?
A. TSH
