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1. A nurse is preparing to give an oral dose of drug X to treat a patient's
high blood pressure. After giving the drug, the nurse finds that it not only
reduces the blood pressure without serious harmful effects, but it also causes
the patient to have nausea and headache. Based on this information, which
property of an ideal drug is this drug lacking?
A. Effectiveness
B. Safety
C. Selectivity
D. Ease of administration: C. Selectivity Correct
The drug is ettective in lowering the blood pressure and safe in that it does not cause harmful ettects. However, as
do most drugs, it causes other ettects besides the one response desired; therefore, it lacks selectivity. The oral form
provides ease of administration.
2. The nurse is preparing to give a drug with certain properties. Which property
of the drug is the most compelling indication that it should not be given?
A. The drug produces an unwanted side effect.
B. The drug is difficult to administer.
C. The drug's effects are reversible.
D. The drug is not effective for its intended purpose.: D. The drug is not ettective for its
intended purpose. Correct
If a drug is not ettective, there is no justification for giving it. Some drugs may be given even though they produce
unwanted side ettects or are diflcult to administer. Reversible action is a desired property for most drugs.
3. Why is it important for drugs to have ease of administration?
A. Fewer administration errors
B. Less risk of side effects
C. Greater chemical stability
D. Greater likelihood of reversibility: A. Fewer administration errors Correct
Ease of administration increases convenience and adherence and can reduce administration errors. Ease of admin-
istration is not related to side ettects, chemical stability, or reversibility.
,4. The nurse teaches a patient not to consume alcohol with nitroglycerine,
because the blood pressure often drops significantly when nitroglycerine is
taken with alcohol. Which drug property does this illustrate?
A. Chemical instability
,B. Drug interaction
C. Reversible action
D. Drug selectivity: B. Drug interaction Correct
When two or more drugs are taken together, they can interact, causing either increased or decreased drug responses.
In this case, alcohol would increase the nitroglycerine response. Chemical instability, reversible action, and drug
selectivity are not related to this situation.
5. When studying the impact a drug has on the body, the nurse is reviewing
what?
A. The drug's pharmacokinetics
B. The drug's selectivity
C. The drug's pharmacodynamics
D. The drug's predictability.: C. The drug's pharmacodynamics Correct
Pharmacodynamics can be thought of as the impact of drugs on the body. Pharmacokinetics describes the movement
of drugs through the body. Selectivity is the ability of a drug to elicit only the response for which it is given. Predictability
is the degree of certainty about how a patient will respond to a certain drug.
6. When studying the effects of drugs in humans, the nurse is learning about
what?
A. Pharmacology
B. Clinical pharmacology
C. Therapeutics
D. Effectiveness: B. Clinical pharmacology Correct
Clinical pharmacology is the study of the ettects of drugs in humans. Pharmacology can be defined as the study of
drugs and their interactions with living systems. Therapeutics, also known as pharmacotherapeutics, is the use of
drugs to diagnose, prevent, or treat disease or to prevent pregnancy. The term ettectiveness indicates that the drug
elicits the intended response or responses.
7. Which statement by a new nurse indicates that further study is indicated?
A. Effectiveness is the most important property a drug can have.
B. There is no such thing as a safe drug.
C. Drugs are defined as illegal substances.
D. There is no such thing as a selective drug; all medications cause side
effects.: Drugs are defined as illegal substances. Correct
A drug is any chemical that can attect living processes. All the other statements are correct.
, 8. What is the ultimate concern for the nurse when administering a drug?
A. Intensity of the response
B. Dosage
C. Route of administration
D. Timing of administration: A. Intensity of the response Correct
The ultimate concern for the nurse when administering a drug is the intensity of the response, which is determined
by the dosage size, route of administration, and timing of administration.
9. What is the objective of drug therapy?
A. To provide maximum benefit with minimal harm
B. To provide minimum benefit with maximum harm
C. To provide total relief of symptoms regardless of harm
D. To provide as much benefit as possible: A. To provide maximum benefit with minimal harm
Correct
The objective of drug therapy is to provide maximum benefit with minimal harm. All drugs have the potential to
produce side ettects. Because drugs are not ideal, we must exercise skill and care if treatment is to result in more
good than harm
10. Characteristics unique to each patient can influence pharmacokinetic and
pharmacodynamic processes. What characteristics may determine the pa-
tient's response to a drug? (Select all that apply.)
A. Age
B. Gender
C. Weight
D. Mood
E. Genetics: A. Age
B. Gender
C. Weight
E. Genetics
Characteristics unique to each patient can influence pharmacokinetic and pharmacodynamic processes and, by doing
so, can help determine the patient's response to a drug. Sources of individual variation include drug interactions;
physiologic variables (eg, age, gender, weight); pathologic variables (especially diminished function of the kidneys
and liver, the major organs of drug elimination); and genetic variables.