UAMS BioChem Exam 2 Test Questions with Answers Rated A
1. Essential amino Amino acids that are necessary for the body but cannot be synthesized by it.
acids
2. Conditional essential An amino acid that is not typically essential but becomes essential under
amino acid certain conditions, such as illness.
3. Albumin -The most abundant protein in plasma.
- decreased in malnutrition
4. Albumin and globu- A/G
lin results are used to
calculate ratio
5. Alpha 1 globulins Proteins that include AFP and Alpha-1 antitrypsin.
6. Alpha-1 antitrypsin -A protein that inhibits protease neutrophil elastase (PNE) and is a positive
function acute phase reactant.
-no smoking
7. Protease neutrophil An enzyme that can destroy alveoli leading to emphysema.
elastase (PNE)
8. Liver Cirrhosis Accumulation of Alpha-1 antitrypsin in the liver.
Beta-Gamma Bridge
9. Haptoglobin func- -binds free hemoglobin to prevent loss of iron into urine
tion
10. Alpha 2 globulins Proteins that include Haptoglobin, A2Macroglobulin, and Ceruloplasmin.
11. Ceruloplasmin -synthesized in the liver.
-Decreased in Wilson's disease.
-Contains copper
,UAMS BioChem Exam 2 Test Questions with Answers Rated A
12. Beta globulins Transferrin, B2Microglobulin, Complement, Fibrinogen, and CRP
13. Transferrin -binds and transports iron to storage sites
-Major component of Beta globulin
14. Gamma globulins Proteins that include Immunoglobins (antibodies) such as IgG, IgA, IgM,
IgD, and IgE.
15. Myoglobin and tro- Both are used as cardiac biomarkers.
ponin
16. B-type natriuretic A marker of congestive heart failure, also elevated with myocardial infarction
peptide (BNP) and in patients undergoing renal dialysis.
17. Biuret method The most widely used protein determination method.
18. Principle of the bi- Cupric (Copper) ions react with peptide bonds to form a violet color, which
uret protein determi- is proportional to the number of peptide bonds and reflects total protein
nation method concentration.
19. Four levels of protein Primary, secondary, tertiary, and quaternary.
structure
20. Alpha-1 antitrypsin
deficiency
21. Liver Cirrhosis A condition characterized by a relative decrease in albumin and a relative
increase in Gamma, noted by the Beta-Gamma Bridge in SPE.
, 22. Cystatin C -marker for GFR
-small protein produced by most nucleated cells in a consistent manner,
unattected by gender, age, eating habits, etc.
23. C-Reactive Protein One of the first acute phase reactants to rise in response to inflammation.
Non specific
24. High-sensitive CRP Used as a cardiovascular risk marker.
25. Monoclonal increase -Perhaps the most significant finding of SPE is monoclonal Ig disease.
-M spike, multiple myeloma, etc.
26. Nephrotic syndrome Condition where the patient loses serum albumin, leading to an increase in
Alpha 2 and Beta.
27. Inflammation Inflammatory conditions cause a decrease in albumin and an increase in
Alpha 1, 2 and Beta (acute phase reactant pattern).
1. Essential amino Amino acids that are necessary for the body but cannot be synthesized by it.
acids
2. Conditional essential An amino acid that is not typically essential but becomes essential under
amino acid certain conditions, such as illness.
3. Albumin -The most abundant protein in plasma.
- decreased in malnutrition
4. Albumin and globu- A/G
lin results are used to
calculate ratio
5. Alpha 1 globulins Proteins that include AFP and Alpha-1 antitrypsin.
6. Alpha-1 antitrypsin -A protein that inhibits protease neutrophil elastase (PNE) and is a positive
function acute phase reactant.
-no smoking
7. Protease neutrophil An enzyme that can destroy alveoli leading to emphysema.
elastase (PNE)
8. Liver Cirrhosis Accumulation of Alpha-1 antitrypsin in the liver.
Beta-Gamma Bridge
9. Haptoglobin func- -binds free hemoglobin to prevent loss of iron into urine
tion
10. Alpha 2 globulins Proteins that include Haptoglobin, A2Macroglobulin, and Ceruloplasmin.
11. Ceruloplasmin -synthesized in the liver.
-Decreased in Wilson's disease.
-Contains copper
,UAMS BioChem Exam 2 Test Questions with Answers Rated A
12. Beta globulins Transferrin, B2Microglobulin, Complement, Fibrinogen, and CRP
13. Transferrin -binds and transports iron to storage sites
-Major component of Beta globulin
14. Gamma globulins Proteins that include Immunoglobins (antibodies) such as IgG, IgA, IgM,
IgD, and IgE.
15. Myoglobin and tro- Both are used as cardiac biomarkers.
ponin
16. B-type natriuretic A marker of congestive heart failure, also elevated with myocardial infarction
peptide (BNP) and in patients undergoing renal dialysis.
17. Biuret method The most widely used protein determination method.
18. Principle of the bi- Cupric (Copper) ions react with peptide bonds to form a violet color, which
uret protein determi- is proportional to the number of peptide bonds and reflects total protein
nation method concentration.
19. Four levels of protein Primary, secondary, tertiary, and quaternary.
structure
20. Alpha-1 antitrypsin
deficiency
21. Liver Cirrhosis A condition characterized by a relative decrease in albumin and a relative
increase in Gamma, noted by the Beta-Gamma Bridge in SPE.
, 22. Cystatin C -marker for GFR
-small protein produced by most nucleated cells in a consistent manner,
unattected by gender, age, eating habits, etc.
23. C-Reactive Protein One of the first acute phase reactants to rise in response to inflammation.
Non specific
24. High-sensitive CRP Used as a cardiovascular risk marker.
25. Monoclonal increase -Perhaps the most significant finding of SPE is monoclonal Ig disease.
-M spike, multiple myeloma, etc.
26. Nephrotic syndrome Condition where the patient loses serum albumin, leading to an increase in
Alpha 2 and Beta.
27. Inflammation Inflammatory conditions cause a decrease in albumin and an increase in
Alpha 1, 2 and Beta (acute phase reactant pattern).
