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Nervous System II

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1. Predict whether ion movement across a postsynaptic membrane will generate an EPSP or IPSP based on its effect on membrane potential relative to threshold. 2. Know that the CNS and PNS work together to sense and respond to the environment, coordinate movement, and regulate internal bodily functions, via afferent & efferent signals. 3. Compare and contrast the Sympathetic and Parasympathetic control over bodily functions. 4. Describe how the nervous system helps regulate body temperature via negative feedback. 5. Understand how simple reflex circuits make fast responses possible and underpin a mouse’s ability (or inability) to escape from a cat (Judy). Signal transduction pathway, Myelin sheath, EPSP & IPSP (literally means Excitatory/Inhibitory PostSynaptic Potential, but we’ll call them EPSP and IPSP), Temporal vs. Spatial summation, afferent vs. efferent neurons, PNS, CNS, Somatic vs. Autonomic responses, Sympathetic vs Parasympathetic, Motor endplate, Acetylcholine, afferent vs. efferent nerves, reciprocal inhibition (in a reflex circuit)

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Animalnervoussystems11 Lecture3 M2
layersof myelin
nervoussystems 1 overview
insulate Imp
fromnodetonode
speeding upconduction
Enfier
Nucleus myelinsheath
cellbo axon
ag
nucleusofgivalce
this s8fi'sregenerated atthese regions
Ap Jaxon

Inhabitants'm'ision sina.itainImitters
chkhnel are re absorbed
begins w actionpotential into thepresynaptic
conductionto axon
cazer
terminal neuron eightnthester

2 Depolarization of axon
terminal opens
Yt it amitia.in afiiatingitvoitageaateacan
PSInaptic
and starting a signaltransduction channels
pathway leceptor membrane
calmodulin activates proteinkinase11 3 vesicles respondto the
influx of cart byfusing w the veryfast
phosphorylates synapsin causing presynaptic membrane and releasing
neurotransmitters into synapticcleft
ftpifyeaqfe É Ée jp t ntoYahfa 4 Neurotransmitters the ligand bind w receptors on
the postsynapticcell that are ligand gated ion channels
their release causing a change in membrane potential
onceliberatedvesicles are shared fuse and
cycled to store neurotransmittersagain
9
tissue cell that supports neurons by
helping neurons fire AP more quickly efficiently
provide nutritional physicalsupport
help establish new neuronal connections feed neurons repair
neurons help clear neurotransmitters help
maintain the ion conc that neurons rely on to fire APs
stain blood brain batrite prevent pathogens toxic compounds in
blood from entering brain
gilial scar repair damage
homeostasis of interstitial fluid and neurons

imitate.latamteinIiieriistite areiow
clear neurotransmitters between synapses
huge component of the central nervoussystem
70 of the CNS by mass
Blood brain barrier
scaffolding structure

Document information

Uploaded on
April 22, 2026
Number of pages
4
Written in
2025/2026
Type
Class notes
Professor(s)
Jeremiah yahn
Contains
All classes

Subjects

  • myelin sheath
  • pns
  • cns
  • sympathetic
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