Neuro ROSH 2026-2027 Questions With
Verified Correct Answers A+ Grade
A 22-year-old nursing student presents to the clinic concerned that she has Guillain-Barré syndrome.
She has a recent history of mononucleosis. Which of the following would be most concerning for this
diagnosis?
BDifficulty swallowing
CDiminished lower extremity reflexesCorrect Answer
DRight arm weakness - C
A 39-year-old man who is a professional football player presents to the clinic with a 3-day history of
headaches, dizziness, irritability, and fatigue. He reports that his symptoms started when he hit his head
during a game. He lost consciousness and had two episodes of vomiting with disorientation and amnesia
up to several hours after the incident. He has not had medical care for his symptoms until now. Which of
the following is the best next step in management for this patient?
ACT scan of the brain Correct Answer
BMRI of the brain
CNeuropsychological testing
DPolysomnography - A
A 55-year-old man presents with proximal muscle pain and weakness in both legs that developed
several days ago. He reports having difficulty climbing stairs in his house. He has a 5-year history of HIV
treated with ritonavir-boosted darunavir plus tenofovir. He had a recent diagnosis of hyperlipidemia and
was placed on simvastatin 3 weeks ago. Physical examination and vital signs are unremarkable. His
creatine kinase level is 500 U/L, serum creatinine is 0.7 mg/dL (61.9 µmol/L), and thyroid-stimulating
hormone is 3.5 µU/mL (3.5 mU/L). His most recent CD4 cell count was 400 cells/µL, and he has stable
suppression of his HIV RNA viral load. Results from a complete count are normal. Which of the following
is the most likely diagnosis?
ADermatomyositis
BDrug-induced myopathyCorrect Answer
CMyasthenia gravis
DRhabdomyolysis - B
,A 37-year-old woman presents to her primary care clinician with reports of pain in her right wrist and
hand. She reports no old injuries or falls and works as an administrative assistant. The nurse practitioner
notes a positive Phalen test and weakness with thumb abduction. Which of the following is the most
effective management?
ACorticosteroid injection
BNonsteroidal anti-inflammatory medication
CPhysical therapy
DSplint wrist - D
A 33-year-old man with schizophrenia treated with haloperidol presents with involuntary, writhing
movements of the tongue and face. Additionally, the patient has choreoathetoid movements of the
trunk and arms. What management is indicated?
ABenztropine
BDiphenhydramine
CLorazepam
DTaper down haloperidol - D
A 74-year-old man presents to the clinic with vision loss. He states that 2 days ago, he could not see out
of his left eye for 3 hours. He reports no pain and states that his vision has since returned to normal. He
has a history of diabetes mellitus and hypertension, and his physical examination is within normal limits.
Which of the following should be included in the initial management?
ACarotid ultrasonography
BElectroencephalogram
COptometry referral for cataracts
DUrgent referral for neurologic evaluation - D
A 35-year-old woman presents to clinic three hours after the onset of a recurrent right frontal pulsatile
headache that starts roughly one hour after experiencing visual loss which has since resolved. You
suspect migraine headache with aura. What are you likely to find on physical examination?
ABitemporal hemianopsia
BNormal visual fieldsCorrect Answer
, CRight homonymous hemianopsia
DRight temporal field loss - B
A patient presents to the clinic with 3 weeks of bilateral dull frontal head pain. He reports no symptoms
of photophobia or phonophobia. He has experienced these symptoms infrequently in the past. After
being assigned a large company project, his symptoms have increased. What is the most likely
diagnosis?
ACluster headache
BMedication overuse headache
CMigraine headache without aura
DTension-type headache - D
An 82-year-old woman presents to clinic with her daughter. Both are concerned with an acute change in
mood, stating that beginning two days ago the patient felt depressed and irritable, described by the
daughter as "having a short fuse." The patient reports not having felt this way in the past, even after her
husband died 5 years ago. She can state her name, address and date properly. She is well groomed and
has been eating and voiding normally, although she does complain of dysuria for the past four days.
Which of the following is the most likely diagnosis?
ADeliriumCorrect Answer
BDementia
CDisorientation
DMajor depression - A
A 60-year-old woman with a history of hypertension presents to your office with a complaint of facial
pain. She describes the pain as right-sided, stabbing, and localized from the corner of her mouth up into
her jaw. It occurs 2-3 times per day and lasts for approximately 30 seconds with some residual burning
sensation afterwards. She notes that she also has increased tearing when these episodes occur. Which
of the following is the most appropriate therapy?
ACarbamazepineCorrect Answer
BClonazepam
CMorphine
DTopiramate - A
Verified Correct Answers A+ Grade
A 22-year-old nursing student presents to the clinic concerned that she has Guillain-Barré syndrome.
She has a recent history of mononucleosis. Which of the following would be most concerning for this
diagnosis?
BDifficulty swallowing
CDiminished lower extremity reflexesCorrect Answer
DRight arm weakness - C
A 39-year-old man who is a professional football player presents to the clinic with a 3-day history of
headaches, dizziness, irritability, and fatigue. He reports that his symptoms started when he hit his head
during a game. He lost consciousness and had two episodes of vomiting with disorientation and amnesia
up to several hours after the incident. He has not had medical care for his symptoms until now. Which of
the following is the best next step in management for this patient?
ACT scan of the brain Correct Answer
BMRI of the brain
CNeuropsychological testing
DPolysomnography - A
A 55-year-old man presents with proximal muscle pain and weakness in both legs that developed
several days ago. He reports having difficulty climbing stairs in his house. He has a 5-year history of HIV
treated with ritonavir-boosted darunavir plus tenofovir. He had a recent diagnosis of hyperlipidemia and
was placed on simvastatin 3 weeks ago. Physical examination and vital signs are unremarkable. His
creatine kinase level is 500 U/L, serum creatinine is 0.7 mg/dL (61.9 µmol/L), and thyroid-stimulating
hormone is 3.5 µU/mL (3.5 mU/L). His most recent CD4 cell count was 400 cells/µL, and he has stable
suppression of his HIV RNA viral load. Results from a complete count are normal. Which of the following
is the most likely diagnosis?
ADermatomyositis
BDrug-induced myopathyCorrect Answer
CMyasthenia gravis
DRhabdomyolysis - B
,A 37-year-old woman presents to her primary care clinician with reports of pain in her right wrist and
hand. She reports no old injuries or falls and works as an administrative assistant. The nurse practitioner
notes a positive Phalen test and weakness with thumb abduction. Which of the following is the most
effective management?
ACorticosteroid injection
BNonsteroidal anti-inflammatory medication
CPhysical therapy
DSplint wrist - D
A 33-year-old man with schizophrenia treated with haloperidol presents with involuntary, writhing
movements of the tongue and face. Additionally, the patient has choreoathetoid movements of the
trunk and arms. What management is indicated?
ABenztropine
BDiphenhydramine
CLorazepam
DTaper down haloperidol - D
A 74-year-old man presents to the clinic with vision loss. He states that 2 days ago, he could not see out
of his left eye for 3 hours. He reports no pain and states that his vision has since returned to normal. He
has a history of diabetes mellitus and hypertension, and his physical examination is within normal limits.
Which of the following should be included in the initial management?
ACarotid ultrasonography
BElectroencephalogram
COptometry referral for cataracts
DUrgent referral for neurologic evaluation - D
A 35-year-old woman presents to clinic three hours after the onset of a recurrent right frontal pulsatile
headache that starts roughly one hour after experiencing visual loss which has since resolved. You
suspect migraine headache with aura. What are you likely to find on physical examination?
ABitemporal hemianopsia
BNormal visual fieldsCorrect Answer
, CRight homonymous hemianopsia
DRight temporal field loss - B
A patient presents to the clinic with 3 weeks of bilateral dull frontal head pain. He reports no symptoms
of photophobia or phonophobia. He has experienced these symptoms infrequently in the past. After
being assigned a large company project, his symptoms have increased. What is the most likely
diagnosis?
ACluster headache
BMedication overuse headache
CMigraine headache without aura
DTension-type headache - D
An 82-year-old woman presents to clinic with her daughter. Both are concerned with an acute change in
mood, stating that beginning two days ago the patient felt depressed and irritable, described by the
daughter as "having a short fuse." The patient reports not having felt this way in the past, even after her
husband died 5 years ago. She can state her name, address and date properly. She is well groomed and
has been eating and voiding normally, although she does complain of dysuria for the past four days.
Which of the following is the most likely diagnosis?
ADeliriumCorrect Answer
BDementia
CDisorientation
DMajor depression - A
A 60-year-old woman with a history of hypertension presents to your office with a complaint of facial
pain. She describes the pain as right-sided, stabbing, and localized from the corner of her mouth up into
her jaw. It occurs 2-3 times per day and lasts for approximately 30 seconds with some residual burning
sensation afterwards. She notes that she also has increased tearing when these episodes occur. Which
of the following is the most appropriate therapy?
ACarbamazepineCorrect Answer
BClonazepam
CMorphine
DTopiramate - A
