NURS 356 EXAM PREPARATION QUESTIONS
WITH FULL RATIONALES 2026
> Interactions? Answer:Increased risk for liver toxicity with isoniazid and
pyrazinamide.
> Metronidazole (Flagyl)? Answer:A broad-spectrum antiparasitic used for
bacterial and protozoal infections.
> Therapeutic Use of Metronidazole? Answer:Used to treat bacterial
infections like Clostridium difficile-associated diarrhea and protozoal
infections.
> CNS Manifestations? Answer:Neurological symptoms that can range
from mild (headache, vertigo) to severe (seizures, peripheral neuropathy).
> Administration of Metronidazole? Answer:Can be given as PO, topical
cream, vaginal gel, or IV.
> Client Instructions for Metronidazole? Answer:Take with food if GI
manifestations occur and report severe symptoms.
> Headache? Answer:A symptom that may occur as an adverse drug
reaction.
> Vertigo? Answer:A symptom that may occur as an adverse drug reaction.
> Seizures? Answer:A symptom that may occur as an adverse drug
reaction.
> Neuropathy? Answer:A symptom that may occur as an adverse drug
reaction.
> Darkened urine? Answer:A harmless adverse drug reaction.
> Metallic taste? Answer:A possible side effect of the drug.
, > Alcohol? Answer:Should be avoided due to potential disulfiram reaction.
> Chloroquine? Answer:A drug class used mainly to treat malaria,
rheumatoid arthritis, and systemic lupus erythematosus.
> MOA of Chloroquine? Answer:Mechanism of action is unknown.
> Therapeutic Use of Chloroquine? Answer:Used to treat chloroquine-
sensitive malaria, amebiasis, and as second-line therapy for rheumatoid
arthritis and SLE.
> Adverse Drug Reactions (ADR) of Chloroquine? Answer:Includes visual
manifestations/impairments and GI manifestations (nausea/vomiting).
> Administration of Chloroquine? Answer:Preferred route is PO; should be
given at least 4 hours before or after antacids or laxatives.
> Client Instructions for Chloroquine? Answer:Wear sunglasses to minimize
visual effects and report any vision changes.
> Contraindications for Chloroquine? Answer:Includes allergy to
chloroquine-related meds and history of visual changes caused by
chloroquine.
> Precautions for Chloroquine? Answer:Includes liver disease and
pregnancy & lactation.
> Interactions of Chloroquine? Answer:Increases risk for hypoglycemia with
antihyperglycemics and QT prolongation with various medications.
> Kidney Functions? Answer:Includes filtering blood plasma, regulating
blood volume and BP, and secreting renin.
> Acute Kidney Injury (AKI)? Answer:Etiology includes pre-renal, intra-
renal, and post-renal pathophysiologies.
> Chronic Kidney Disease (CKD)? Answer:A slower and more progressive
disease resulting from years of kidney injury.
WITH FULL RATIONALES 2026
> Interactions? Answer:Increased risk for liver toxicity with isoniazid and
pyrazinamide.
> Metronidazole (Flagyl)? Answer:A broad-spectrum antiparasitic used for
bacterial and protozoal infections.
> Therapeutic Use of Metronidazole? Answer:Used to treat bacterial
infections like Clostridium difficile-associated diarrhea and protozoal
infections.
> CNS Manifestations? Answer:Neurological symptoms that can range
from mild (headache, vertigo) to severe (seizures, peripheral neuropathy).
> Administration of Metronidazole? Answer:Can be given as PO, topical
cream, vaginal gel, or IV.
> Client Instructions for Metronidazole? Answer:Take with food if GI
manifestations occur and report severe symptoms.
> Headache? Answer:A symptom that may occur as an adverse drug
reaction.
> Vertigo? Answer:A symptom that may occur as an adverse drug reaction.
> Seizures? Answer:A symptom that may occur as an adverse drug
reaction.
> Neuropathy? Answer:A symptom that may occur as an adverse drug
reaction.
> Darkened urine? Answer:A harmless adverse drug reaction.
> Metallic taste? Answer:A possible side effect of the drug.
, > Alcohol? Answer:Should be avoided due to potential disulfiram reaction.
> Chloroquine? Answer:A drug class used mainly to treat malaria,
rheumatoid arthritis, and systemic lupus erythematosus.
> MOA of Chloroquine? Answer:Mechanism of action is unknown.
> Therapeutic Use of Chloroquine? Answer:Used to treat chloroquine-
sensitive malaria, amebiasis, and as second-line therapy for rheumatoid
arthritis and SLE.
> Adverse Drug Reactions (ADR) of Chloroquine? Answer:Includes visual
manifestations/impairments and GI manifestations (nausea/vomiting).
> Administration of Chloroquine? Answer:Preferred route is PO; should be
given at least 4 hours before or after antacids or laxatives.
> Client Instructions for Chloroquine? Answer:Wear sunglasses to minimize
visual effects and report any vision changes.
> Contraindications for Chloroquine? Answer:Includes allergy to
chloroquine-related meds and history of visual changes caused by
chloroquine.
> Precautions for Chloroquine? Answer:Includes liver disease and
pregnancy & lactation.
> Interactions of Chloroquine? Answer:Increases risk for hypoglycemia with
antihyperglycemics and QT prolongation with various medications.
> Kidney Functions? Answer:Includes filtering blood plasma, regulating
blood volume and BP, and secreting renin.
> Acute Kidney Injury (AKI)? Answer:Etiology includes pre-renal, intra-
renal, and post-renal pathophysiologies.
> Chronic Kidney Disease (CKD)? Answer:A slower and more progressive
disease resulting from years of kidney injury.
