MLT 126 - immunology & serology -Final Exam Review Guide (Latest 2024/2025) (500 Q&A)

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Part I: Basic Immunologic Mechanisms
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1. Highlights of Innate and Adaptive Immune Systems
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2. Soluble Mediators of the Immune System
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3. Antigens and Antibodies r r




4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
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Part II: The Theory of Immunologic and Serologic Procedures
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5. Basic Safety in the Immunology-Serology Laboratory
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6. Quality Assurance and Quality Control Practices
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7. Basic Serologic Laboratory: Techniques and Clinical Applications
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8. Precipitation and Particle Agglutination Methods r r r r




9. Electrophoresis Techniques r




10. Labeling Techniques in Immunoassay r r r




11. Flow Cytometry r




12. Molecular Laboratory Techniques r r



Part III: Immunologic Manifestations of Infectious Diseases
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13. Infectious Diseases: Overview & TORCH Diseases r r r r r




14. Streptococcal Infections r




15. Syphilis

16. Vector-Borne Diseases r




17. Infectious Mononucleosis r




18. Viral Hepatitis r



Part IV: Immune Disorders
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19. Primary and Acquired (Secondary) Immune Deficiencies
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20. Hypersensitivity Reactions r




21. Immunoproliferative Disorders r




22. Tolerance, Autoimmunity and Autoimmune Disorders r r r r




23. Systemic Lupus Erythematosus r r

,24. Rheumatoid Arthritis r



Part V: Transplantation & Tumor Immunology
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25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
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26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
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Part VI: Vaccines
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27. Primer on Vaccines r r




Chapter 01: Highlights of the Innate and Adaptive Immune Systems
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MULTIPLE CHOICE r




1. The―father‖ofimmunologyisgenerallyconsideredto be
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a. Koch.
b. Pasteur.
c. Gram.
d. Salk.

ANS: B r

, Louis Pasteur is generally considered to be the ―father of immunology.‖
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DIF: Cognitive Level: I r r




2. An early form of immunization was practiced by the
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a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. r




ANS: C r



Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried powders
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derived from the crusts of smallpox lesions.
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DIF: Cognitive Level: I r r




3. A specific function of the immune system is to
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a. recognize self from nonself. r r r



b. defend the body against nonself. r r r r



c. amplify specific functions. r r



d. Both A and B. r r r




ANS: D r



The function ofthe immune system is to recognize self from nonself and defend the body against
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nonself. Such a system is necessary for survival. The immune system also has nonspecific
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effector mechanisms that usually amplify the specific functions. Nonspecific components of the
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immune system include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble
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factors (e.g., complement).
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DIF: Cognitive Level: I r r




4. An undesirable consequence of immunity is
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a. natural resistance. r



b. acquired resistance to infectious diseases. r r r r