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NUR 4256C HESI RN ADVANCED PATHOPHYSIOLOGY 2024–2025 NURSING REVIEW MATERIAL – PRACTICE QUESTIONS WITH ANSWERS

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This document covers advanced pathophysiology concepts aligned with the NUR 4256C HESI RN curriculum for the 2024–2025 academic year. It includes high-yield nursing content focused on disease processes across major body systems such as cardiovascular, respiratory, renal, endocrine, neurological, and immune systems. The material is designed as a structured study and revision aid for exam preparation, including practice-style questions with detailed answers and rationales to support clinical reasoning. It is useful for reinforcing core concepts commonly tested in HESI and NCLEX-style examinations.

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NUR 425 PATHOPHYSIOLOGY
Course
NUR 425 PATHOPHYSIOLOGY

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NUR 4256C HESI RN ADVANCED PATHOPHYSIOLOGY
2024–2025 NURSING REVIEW MATERIAL – PRACTICE
QUESTIONS WITH ANSWERS
What does Frank-Starling law predict about heart function?

a. More afterload, less perfusion

b. More preload, increased contraction

c. Less afterload, more ischemia

d. More contraction, less output

b. More preload, increased contraction




What is the function of the glomerulus?

a. Filter blood

b. Activate vitamin D

c. Actively reabsorb glucose

d. Regulate sodium excretion

a. Filter blood




What neurotransmitter changes in brain are associated with mood depression?

a. High dopamine

b. Low serotonin

c. Increase acetylcholine (ACh)

d. Low norepinephrine

b. Low serotonin

,Which is true about HIV transmission? (select all that apply)

a. It is transmitted via breast milk

b. It has been transmitted via aerosol route

c. It cannot be transmitted during pregnancy until delivery

d. It can be transmitted by sharing needles

e. Saliva is a common route for transmission

f. It can live for 48 hrs on surfaces outside the body

a. It is transmitted via breast milk

d. It can be transmitted by sharing needles




Which of the following is associated with initial HIV infection?

a. Flulike symptoms and rash

b. Decreased CD4 T cells

c. Seroconversion within 3-6 days

d. CD4 T cell count < 200 per mcg/L

a. Flulike symptoms and rash




Which of the following statement is true regarding HIV testing?

a. The first test is the electrophoresis

b. The new rapid finger stick tests give results in 20 min

c. All patient's w/a positive test must have the ELISA performed

d. The Western blot is the initial test

,b. The new rapid finger stick tests give results in 20 min




Which of the following are required for erythropoieses? (select all that apply)

a. Vitamin K

b. Vitamin B12

c. Folate

d. Vitamin E

e. Niacin

f. Ascorbic acid (Vitamin C)

b. Vitamin B12

c. Folate

e. Niacin

f. Ascorbic acid (Vitamin C)




What causes a shift of the oxyhemoglobin curve to the right?

a. Chronic disease.

b. Increased pH

c. Decreased H+ ions

d. Decreased temperature

a. Chronic disease




What is the term used for an excess of RBCs?

a. Anemia

, b. Polycythemia

c. Pancytopenia

d. Granulocytosis

b. Polycythemia




What is false regarding aplastic anemia?

a. It runs in families

b. It causes overproduction of hematopoietic tissue

c. It is characterized by pancytopenia

d. It is caused by viral infections

b. It causes overproduction of hematopoietic tissue




Which of the following is a macrocytic anemia?

a. Thalassemia

b. Anemia of chronic renal failure

c. Iron deficiency anemia

d. Pernicious anemia

d. Pernicious anemia




Which of the following are appropriate for sickle cell anemia?

a. Early spleen removal

b. Acetaminophen (Tylenol) for fever

c. Dehydration to prevent vaso-occlusive crises

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Institution
NUR 425 PATHOPHYSIOLOGY
Course
NUR 425 PATHOPHYSIOLOGY

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April 17, 2026
Number of pages
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