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NR565 Week 8 Final Exam: NR 565 Advanced
Pharmacology Fundamentals Complete Question 1- 180
(Actual Exam Proctored via Examplify) With Correct
Answers | 100% Pass Guaranteed | Graded A +
A patient with renal failure requires dosage adjustments for which type of
medication?
A. Drugs excreted unchanged by the kidneys ✓
B. Drugs metabolized by the liver
C. Topical corticosteroids
D. Sublingual nitroglycerin
Explanation: Drugs primarily cleared unchanged through the kidneys accumulate
when renal function declines, requiring dosage reduction.
Which receptor type is primarily targeted by beta-blockers?
A. Alpha-1 adrenergic
B. Beta-adrenergic ✓
C. Muscarinic
D. Dopaminergic
,2
Explanation: Beta-blockers block beta-adrenergic receptors in the heart, reducing
heart rate, myocardial contractility, and blood pressure.
Select all that apply: Common side effects of ACE inhibitors include:
A. Dry cough ✓B. Hyperkalemia ✓
C. Hypoglycemia
D. Bradycardia
Explanation: ACE inhibitors cause dry cough from bradykinin accumulation and
can increase potassium retention.
Which of the following best describes a partial agonist?
A. Produces no effect when binding to a receptor
B. Produces the same maximal effect as a full agonist
C. Produces a smaller maximal response, even when all receptors are occupied ✓
D. Blocks receptor activation
Explanation: Partial agonists bind to receptors but produce less than maximal
activation, even at high doses.
Which of the following medications is contraindicated in pregnancy?
A. Labetalol
B. Methyldopa
C. ACE inhibitors ✓
,3
D. Insulin
Explanation: ACE inhibitors are teratogenic and can cause fetal renal damage,
especially in the second and third trimesters.
Which neurotransmitter is primarily involved in Parkinson’s disease?
A. Acetylcholine
B. Dopamine ✓
C. Serotonin
D. GABA
Explanation: Parkinson’s disease is caused by dopamine deficiency in the
substantia nigra, leading to motor dysfunction.
A nurse observes bleeding gums in a patient on warfarin. Which lab value should
be monitored?
A. BUN
B. PT/INR ✓
C. Serum creatinine
D. AST/ALT
Explanation: PT/INR reflects warfarin’s anticoagulant effect; elevated levels
indicate risk of bleeding.
What is the mechanism of action of calcium channel blockers?
, 4
A. Increase heart contractility
B. Block calcium entry into cardiac and smooth muscle cells ✓
C. Stimulate beta receptors
D. Increase sodium reabsorption
Explanation: CCBs inhibit calcium influx, reducing myocardial contractility and
promoting vasodilation.
Select all that apply: Which drugs require monitoring for hypokalemia?
A. Loop diuretics ✓B. Thiazide diuretics ✓
C. ACE inhibitors
D. Potassium-sparing diuretics
Explanation: Loop and thiazide diuretics promote potassium loss, increasing the
risk of hypokalemia.
Which of the following adverse reactions is associated with statins?
A. Bradycardia
B. Rhabdomyolysis ✓
C. Hypokalemia
D. Hypertension
Explanation: Statins can cause muscle breakdown, leading to rhabdomyolysis.
A patient on digoxin presents with nausea, confusion, and visual disturbances.
What is the likely cause?
NR565 Week 8 Final Exam: NR 565 Advanced
Pharmacology Fundamentals Complete Question 1- 180
(Actual Exam Proctored via Examplify) With Correct
Answers | 100% Pass Guaranteed | Graded A +
A patient with renal failure requires dosage adjustments for which type of
medication?
A. Drugs excreted unchanged by the kidneys ✓
B. Drugs metabolized by the liver
C. Topical corticosteroids
D. Sublingual nitroglycerin
Explanation: Drugs primarily cleared unchanged through the kidneys accumulate
when renal function declines, requiring dosage reduction.
Which receptor type is primarily targeted by beta-blockers?
A. Alpha-1 adrenergic
B. Beta-adrenergic ✓
C. Muscarinic
D. Dopaminergic
,2
Explanation: Beta-blockers block beta-adrenergic receptors in the heart, reducing
heart rate, myocardial contractility, and blood pressure.
Select all that apply: Common side effects of ACE inhibitors include:
A. Dry cough ✓B. Hyperkalemia ✓
C. Hypoglycemia
D. Bradycardia
Explanation: ACE inhibitors cause dry cough from bradykinin accumulation and
can increase potassium retention.
Which of the following best describes a partial agonist?
A. Produces no effect when binding to a receptor
B. Produces the same maximal effect as a full agonist
C. Produces a smaller maximal response, even when all receptors are occupied ✓
D. Blocks receptor activation
Explanation: Partial agonists bind to receptors but produce less than maximal
activation, even at high doses.
Which of the following medications is contraindicated in pregnancy?
A. Labetalol
B. Methyldopa
C. ACE inhibitors ✓
,3
D. Insulin
Explanation: ACE inhibitors are teratogenic and can cause fetal renal damage,
especially in the second and third trimesters.
Which neurotransmitter is primarily involved in Parkinson’s disease?
A. Acetylcholine
B. Dopamine ✓
C. Serotonin
D. GABA
Explanation: Parkinson’s disease is caused by dopamine deficiency in the
substantia nigra, leading to motor dysfunction.
A nurse observes bleeding gums in a patient on warfarin. Which lab value should
be monitored?
A. BUN
B. PT/INR ✓
C. Serum creatinine
D. AST/ALT
Explanation: PT/INR reflects warfarin’s anticoagulant effect; elevated levels
indicate risk of bleeding.
What is the mechanism of action of calcium channel blockers?
, 4
A. Increase heart contractility
B. Block calcium entry into cardiac and smooth muscle cells ✓
C. Stimulate beta receptors
D. Increase sodium reabsorption
Explanation: CCBs inhibit calcium influx, reducing myocardial contractility and
promoting vasodilation.
Select all that apply: Which drugs require monitoring for hypokalemia?
A. Loop diuretics ✓B. Thiazide diuretics ✓
C. ACE inhibitors
D. Potassium-sparing diuretics
Explanation: Loop and thiazide diuretics promote potassium loss, increasing the
risk of hypokalemia.
Which of the following adverse reactions is associated with statins?
A. Bradycardia
B. Rhabdomyolysis ✓
C. Hypokalemia
D. Hypertension
Explanation: Statins can cause muscle breakdown, leading to rhabdomyolysis.
A patient on digoxin presents with nausea, confusion, and visual disturbances.
What is the likely cause?
