PASSMEDICINE (PASSMED) COMPREHENSIVE REVISION 2026/2027 | 100%
VERIFIED EXAM QUESTIONS & ANSWERS | LATEST UPDATED
A 37-year-old female presents to her general practitioner with a 2-month history
of progressive fatigue. She has a background medical history of type-1 diabetes
mellitus.Her doctor orders a full blood count, which is reported as follows:
Hb78 g/L (115 - 160)
Mean cell volume136 fl (82-100)
Platelets156 * 109/L (150 - 400)
WBC4.2 * 109/L (4.0 - 11.0)
Based on the above information, testing for which of the following antibodies is
most appropriate to aid diagnosis? - ANSWER Intrinsic factor antibodies are
more useful than gastric parietal cell antibodies when investigating vitamin B12
deficiency, given low specificity of gastric parietal cell antibodies
I thought it would be Anti-TTG antibodies but these are used as a screening test
for coeliac disease. Coeliac disease can cause anaemia. However, it tends to be
a microcytic (low mean cell volume) anaemia caused by iron deficiency due to
malabsorption.
A SABA or SAMA is the first-line pharmacological treatment of COPD eg. -
ANSWER ipratropium
In type 1 diabetes, we would expect a ? level of plasma C-peptide - ANSWER
low or undetectable level
due to absolute insulin deficiency
if high = type 2
UTI treatment first line - ANSWER Trimethoprim
Nitrofurantoin
3 days for simple
7 days for men/ pregnancy
pregnancy:
Nitrofurantoin (avoid in the third trimester)
Amoxicillin (only after sensitivities are known)
Cefalexin
VERIFIED EXAM QUESTIONS & ANSWERS | LATEST UPDATED
A 37-year-old female presents to her general practitioner with a 2-month history
of progressive fatigue. She has a background medical history of type-1 diabetes
mellitus.Her doctor orders a full blood count, which is reported as follows:
Hb78 g/L (115 - 160)
Mean cell volume136 fl (82-100)
Platelets156 * 109/L (150 - 400)
WBC4.2 * 109/L (4.0 - 11.0)
Based on the above information, testing for which of the following antibodies is
most appropriate to aid diagnosis? - ANSWER Intrinsic factor antibodies are
more useful than gastric parietal cell antibodies when investigating vitamin B12
deficiency, given low specificity of gastric parietal cell antibodies
I thought it would be Anti-TTG antibodies but these are used as a screening test
for coeliac disease. Coeliac disease can cause anaemia. However, it tends to be
a microcytic (low mean cell volume) anaemia caused by iron deficiency due to
malabsorption.
A SABA or SAMA is the first-line pharmacological treatment of COPD eg. -
ANSWER ipratropium
In type 1 diabetes, we would expect a ? level of plasma C-peptide - ANSWER
low or undetectable level
due to absolute insulin deficiency
if high = type 2
UTI treatment first line - ANSWER Trimethoprim
Nitrofurantoin
3 days for simple
7 days for men/ pregnancy
pregnancy:
Nitrofurantoin (avoid in the third trimester)
Amoxicillin (only after sensitivities are known)
Cefalexin
