Test Bank
For Pathophysiology The Biological Basis For
Disease In Adults And Children 8th Edition By
Kathryn L. Mccance Latest Edition 2026
NURSINGTB.COM
,Table Of Contents
Part 1: Central Concepts Of Pathophysiology: Cells And Tissues
Unit I: The Cell
1. Cellular Biology
2. Altered Cellular And Tissue Biology: Environmental Agents
3. The Cellular Environment: Fluids And Electrolytes, Acids And Bases
Unit Ii: Genes And Gene-Environment Interaction
4. Genes And Genetic Diseases
5. Genes, Environment-Lifestyle, And Common Diseases
6. Epigenetics And Disease
Unit Iii: Mechanisms Of Self-Defense
7. Innate Immunity: Inflammation
8. Adaptive Immunity
9. Alterations In Immunity And Inflammation
10. Infection
11. Stress And Disease
Unit Iv. Cellular Proliferation: Cancer
12. Cancer Biology
13. Cancer Epidemiology
14. Cancer In Children
Part 2: Pathophysiologic Alterations: Organs And Systems
Unit V: The Neurologic System
15. Structure And Function Of The Neurologic System
16. Pain, Temperature Regulation, Sleep, And Sensory Function
17. Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function
18. Disorders Of The Central And Peripheral Nervous Systems And The Neuromuscular Junction
19. Neurobiology Of Schizophrenia, Mood Disorders, And Anxiety Disorders
20. Alterations Of Neurologic Function In Children
Unit Vi: The Endocrine System
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,21. Mechanisms Of Hormonal Regulation
22. Alterations Of Hormonal Regulation
23. Obesity And Disorders Of Nutrition
Unit Vii: The Reproductive Systems
24. Structure And Function Of The Reproductive Systems
25. Alterations Of The Female Reproductive System
26. Alterations Of The Male Reproductive System
27. Sexually Transmitted Infections
Unit Viii: The Hematologic System
28. Structure And Function Of The Hematologic System
29. Alterations Of Erythrocyte, Platelet, And Hemostatic Function
30. Alterations Of Leukocyte And Lymphoid Function
31. Alterations Of Hematologic Function In Children
Unit Ix: The Cardiovascular And Lymphatic Systems
32. Structure And Function Of The Cardiovascular And Lymphatic Systems
33. Alterations Of Cardiovascular Function
34. Alterations Of Cardiovascular Function In Children
Unit X: The Pulmonary System
35. Structure And Function Of The Pulmonary System
36. Alterations Of Pulmonary Function
37. Alterations Of Pulmonary Function In Children
Unit Xi: The Renal And Urologic Systems
38. Structure And Function Of The Renal And Urologic Systems
39. Alterations Of Renal And Urinary Function
40. Alterations Of Renal And Urinary Tract Function In Children
Unit Xii: The Digestive System
41. Structure And Function Of The Digestive System
42. Alterations Of Digestive Function
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,43. Alterations Of Digestive Function In Children
Unit Xiii: The Musculoskeletal System
44. Structure And Function Of The Musculoskeletal System
45. Alterations Of Musculoskeletal Function
46. Alterations Of Musculoskeletal Function In Children
Unit Xiv: The Integumentary System
47. Structure, Function, And Disorders Of The Integument
48. Alterations Of The Integument In Children
Unit Xv: Multiple Interacting Systems
49. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Adults
50. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Children
NURSINGTB.COM
,Pathophysiology 8th edition mccance test bank chapter 1
To 50
Chapter 1: cellular biology
Multiple
choice
1. Which statement best describes the cellular function of metabolic
absorption?
a. Cells can produce proteins. C. Cells can take in and use nutrients.
b. Cells can secrete digestive enzymes. D. Cells can synthesize fats.
Ans: c
In metabolic absorption, all cells take in and use nutrients and other
substances from theirsurroundings. The remaining options are not
inclusive in their descriptions of cellular metabolic absorption.
Pts: 1 ref: page 2
2. Most of a cell’s genetic information, including rna and dna, is contained
in the:
a. Mitochondria c. Nucleolus
b. Ribosome d. Lysosome
Ans: c
The nucleus contains the nucleolus, a small dense structure
composed largely of rna, most of the cellular dna, and the dna-binding
proteins, such as the histones, which regulate its activity. The other
options do not contain most of a cell’s genetic information.
Pts: 1 ref: page 2
3. Which component of the cell prodnuucerssihnygd rt obg.cenomperoxide (h2o2)
by using oxygen to remove hydrogen atoms from specific
substrates in an oxidative reaction?
a. Lysosomes c. Ribosomes
b. Peroxisomes d. Oxyhydrosomes
Ans: b
Peroxisomes are so named because they usually contain enzymes that
use oxygen to remove hydrogen atoms from specific substrates in an
oxidative reaction that produces h2o2, which is a powerful oxidant and
potentially destructive if it accumulates or escapes from peroxisomes.
Ribosomes are rna-protein complexes (nucleoproteins) that are
synthesized in the nucleolus and secreted into the cytoplasm through
pores in the nuclear envelope called nuclear pore complexes. Lysosomes
are saclike structures that originate from the golgi complex and contain
NURSINGTB.COM
, more than 40 digestive enzymes called hydrolases, which catalyze
bonds in proteins, lipids, nucleic acids, and carbohydrates.
Oxyhydrosomesare involved in enzyme production.
Pts: 1 ref: page 8
4. Which cell component is capable of cellular autodigestion when
it is released during cellinjury?
a. Ribosome c. Smooth endoplasmic reticulum
b. Golgi complex d. Lysosomes
Ans: d
The lysosomal membrane acts as a protective shield between the
powerful digestive enzymes within the lysosome and the cytoplasm,
preventing their leakage into the cytoplasmic matrix. Disruption of the
membrane by various treatments or cellular injury leads to a release
of the lysosomal enzymes, which can then react with their specific
substrates, causing cellular self- digestion. The other options do not
correctly describe thisprocess.
Pts: 1 ref: pages 7-8
5. What is the sequence of steps in the development of a digestive
enzyme by the pancreascells from the initial transcription to the
release from the cell?
a. The enzyme is transcribed from dna by rna in the
nucleus, proceeds to theribosome for synthesis, and is
transported in a secretory vesicle to the cell membrane.
b. The enzyme is transcribed from rna by dna in the nucleus,
proceeds to the lysosome for synthesis, and is transported
in an encapsulated membrane to the cellmembrane.
c. The enzyme is transcribed by the mitochondria in the
nucleus, proceeds to the ribosome for synthesis, and is
transported in a cytoskeleton to the cell membrane.
d. The enzyme is transcribed from dna by rna in the nucleus,
proceeds to the golgi complex for synthesis, and is
transported in a cytosol to the cell membrane.
Ans: a
The enzyme is transcribed from dna by rna in the nucleus, proceeds
to the ribosomefor synthesis, and is transported in a secretory
vesicle to the cell membrane. The other options do not correctly
describe this process.
Nursingtb.com
Pts: 1 ref: page 7 | figure 1-5
6. During which phase of the cell cycle is dna synthesized?
a. G1 c. G2
NURSINGTB.COM
For Pathophysiology The Biological Basis For
Disease In Adults And Children 8th Edition By
Kathryn L. Mccance Latest Edition 2026
NURSINGTB.COM
,Table Of Contents
Part 1: Central Concepts Of Pathophysiology: Cells And Tissues
Unit I: The Cell
1. Cellular Biology
2. Altered Cellular And Tissue Biology: Environmental Agents
3. The Cellular Environment: Fluids And Electrolytes, Acids And Bases
Unit Ii: Genes And Gene-Environment Interaction
4. Genes And Genetic Diseases
5. Genes, Environment-Lifestyle, And Common Diseases
6. Epigenetics And Disease
Unit Iii: Mechanisms Of Self-Defense
7. Innate Immunity: Inflammation
8. Adaptive Immunity
9. Alterations In Immunity And Inflammation
10. Infection
11. Stress And Disease
Unit Iv. Cellular Proliferation: Cancer
12. Cancer Biology
13. Cancer Epidemiology
14. Cancer In Children
Part 2: Pathophysiologic Alterations: Organs And Systems
Unit V: The Neurologic System
15. Structure And Function Of The Neurologic System
16. Pain, Temperature Regulation, Sleep, And Sensory Function
17. Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function
18. Disorders Of The Central And Peripheral Nervous Systems And The Neuromuscular Junction
19. Neurobiology Of Schizophrenia, Mood Disorders, And Anxiety Disorders
20. Alterations Of Neurologic Function In Children
Unit Vi: The Endocrine System
NURSINGTB.COM
,21. Mechanisms Of Hormonal Regulation
22. Alterations Of Hormonal Regulation
23. Obesity And Disorders Of Nutrition
Unit Vii: The Reproductive Systems
24. Structure And Function Of The Reproductive Systems
25. Alterations Of The Female Reproductive System
26. Alterations Of The Male Reproductive System
27. Sexually Transmitted Infections
Unit Viii: The Hematologic System
28. Structure And Function Of The Hematologic System
29. Alterations Of Erythrocyte, Platelet, And Hemostatic Function
30. Alterations Of Leukocyte And Lymphoid Function
31. Alterations Of Hematologic Function In Children
Unit Ix: The Cardiovascular And Lymphatic Systems
32. Structure And Function Of The Cardiovascular And Lymphatic Systems
33. Alterations Of Cardiovascular Function
34. Alterations Of Cardiovascular Function In Children
Unit X: The Pulmonary System
35. Structure And Function Of The Pulmonary System
36. Alterations Of Pulmonary Function
37. Alterations Of Pulmonary Function In Children
Unit Xi: The Renal And Urologic Systems
38. Structure And Function Of The Renal And Urologic Systems
39. Alterations Of Renal And Urinary Function
40. Alterations Of Renal And Urinary Tract Function In Children
Unit Xii: The Digestive System
41. Structure And Function Of The Digestive System
42. Alterations Of Digestive Function
NURSINGTB.COM
,43. Alterations Of Digestive Function In Children
Unit Xiii: The Musculoskeletal System
44. Structure And Function Of The Musculoskeletal System
45. Alterations Of Musculoskeletal Function
46. Alterations Of Musculoskeletal Function In Children
Unit Xiv: The Integumentary System
47. Structure, Function, And Disorders Of The Integument
48. Alterations Of The Integument In Children
Unit Xv: Multiple Interacting Systems
49. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Adults
50. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Children
NURSINGTB.COM
,Pathophysiology 8th edition mccance test bank chapter 1
To 50
Chapter 1: cellular biology
Multiple
choice
1. Which statement best describes the cellular function of metabolic
absorption?
a. Cells can produce proteins. C. Cells can take in and use nutrients.
b. Cells can secrete digestive enzymes. D. Cells can synthesize fats.
Ans: c
In metabolic absorption, all cells take in and use nutrients and other
substances from theirsurroundings. The remaining options are not
inclusive in their descriptions of cellular metabolic absorption.
Pts: 1 ref: page 2
2. Most of a cell’s genetic information, including rna and dna, is contained
in the:
a. Mitochondria c. Nucleolus
b. Ribosome d. Lysosome
Ans: c
The nucleus contains the nucleolus, a small dense structure
composed largely of rna, most of the cellular dna, and the dna-binding
proteins, such as the histones, which regulate its activity. The other
options do not contain most of a cell’s genetic information.
Pts: 1 ref: page 2
3. Which component of the cell prodnuucerssihnygd rt obg.cenomperoxide (h2o2)
by using oxygen to remove hydrogen atoms from specific
substrates in an oxidative reaction?
a. Lysosomes c. Ribosomes
b. Peroxisomes d. Oxyhydrosomes
Ans: b
Peroxisomes are so named because they usually contain enzymes that
use oxygen to remove hydrogen atoms from specific substrates in an
oxidative reaction that produces h2o2, which is a powerful oxidant and
potentially destructive if it accumulates or escapes from peroxisomes.
Ribosomes are rna-protein complexes (nucleoproteins) that are
synthesized in the nucleolus and secreted into the cytoplasm through
pores in the nuclear envelope called nuclear pore complexes. Lysosomes
are saclike structures that originate from the golgi complex and contain
NURSINGTB.COM
, more than 40 digestive enzymes called hydrolases, which catalyze
bonds in proteins, lipids, nucleic acids, and carbohydrates.
Oxyhydrosomesare involved in enzyme production.
Pts: 1 ref: page 8
4. Which cell component is capable of cellular autodigestion when
it is released during cellinjury?
a. Ribosome c. Smooth endoplasmic reticulum
b. Golgi complex d. Lysosomes
Ans: d
The lysosomal membrane acts as a protective shield between the
powerful digestive enzymes within the lysosome and the cytoplasm,
preventing their leakage into the cytoplasmic matrix. Disruption of the
membrane by various treatments or cellular injury leads to a release
of the lysosomal enzymes, which can then react with their specific
substrates, causing cellular self- digestion. The other options do not
correctly describe thisprocess.
Pts: 1 ref: pages 7-8
5. What is the sequence of steps in the development of a digestive
enzyme by the pancreascells from the initial transcription to the
release from the cell?
a. The enzyme is transcribed from dna by rna in the
nucleus, proceeds to theribosome for synthesis, and is
transported in a secretory vesicle to the cell membrane.
b. The enzyme is transcribed from rna by dna in the nucleus,
proceeds to the lysosome for synthesis, and is transported
in an encapsulated membrane to the cellmembrane.
c. The enzyme is transcribed by the mitochondria in the
nucleus, proceeds to the ribosome for synthesis, and is
transported in a cytoskeleton to the cell membrane.
d. The enzyme is transcribed from dna by rna in the nucleus,
proceeds to the golgi complex for synthesis, and is
transported in a cytosol to the cell membrane.
Ans: a
The enzyme is transcribed from dna by rna in the nucleus, proceeds
to the ribosomefor synthesis, and is transported in a secretory
vesicle to the cell membrane. The other options do not correctly
describe this process.
Nursingtb.com
Pts: 1 ref: page 7 | figure 1-5
6. During which phase of the cell cycle is dna synthesized?
a. G1 c. G2
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