Test Bank For Clayton's Basic Pharmacology for Nurses 19th Edition By Bruce Clayton, Michelle Willihnganz, Samuel Gurevitz ( ) / 9780323796309 / Chapter 1-48 / Complete Questions and Answers A+

Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Com
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plete

,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnga
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nz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE CHOICE +y




1. Which name identifies a drug listed by the US Food a
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ndDrug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C +y


The official name is the name under which a drug is list
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ed by the FDA. The brand name, or trademark, is the na
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me given to a drug by its manufacturer. The nonproprietar
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y, or generic, name is provided by the United States Ado
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pted Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 9 +y +y +y +y


OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective C
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areEnvironment TOP: Nursing Process Step: Assessment
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CON: +y


Patient Education +y




2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database +y +y +y


c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts +y +y




ANS: C +y


United States Pharmacopoeia/National Formulary contains information specific to nutrition
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alsupplements. USP Dictionary of USAN & International Drug Names is a compilation of
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drugnames, pronunciation guide, and possible future FDA approved drugs; it does not inc
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lude nutritional supplements. Natural Medicines Comprehensive Database contains
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evidence-
based information on herbal medicines and herbal combination products; it does notinclude
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information specific to nutritional supplements. Drug Interaction Facts contains comprehe
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nsive information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 +y +y + y +y


OBJ: 3NAT: NCLEX Client Needs Category: Physiological Int
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egrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons +y +y +y

,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
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on
b. Drug Interaction Facts +y +y


c. Handbook on Injectable Drugs +y +y +y


d. Martindale—The Complete Drug Reference +y +y +y




ANS: A +y


Drug Facts and Comparisons contains drug monographs that describe all drugs in
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atherapeutic class. Monographs are formatted as tables to allow comparison of sim
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ilarproducts, brand names, manufacturers, cost indices, and available dosage forms
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Online version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 +y +y + y +y +y +y


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
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4. Which drug reference contains monographs about virtually every single-
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entity drug availablein the United States and describes therapeutic uses of drugs, includin
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g approved and unapproved uses?
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a. Martindale: The Complete Drug Reference +y +y +y +y


b. AHFS Drug Information +y +y


c. Drug Reference +y


d. Drug Facts and Comparisons +y +y +y




ANS: B +y


AHFS Drug Information contains monographs about virtually every single-
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entity drug available in the United States and describes therapeutic uses of drugs, including
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approved andunapproved uses.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 +y +y + y +y +y +y


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning
+ y CON: Safety | Patient Education | Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a
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standard, comprehensive, up-to- +y +y


date look up and downloadable resource about medicines?
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a. American Drug Index +y +y


b. American Hospital Formulary +y +y


c. DailyMed
d. Drug Reference +y




ANS: C +y


DailyMed makes available to healthcare providers and the public a standard, comprehensi
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ve,up-to- +
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date look up and downloadable resource about medicines. The American Drug Index isnot
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appropriate for patient use. The American Hospital Formulary is not appropriate for pati
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ent use. The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 +y +y + y +y +y +y +y


OBJ: 3NAT: NCLEX Client Needs Category: Physiological Int
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egrity
TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) +y +y +y +y +y +y


b. Durham Humphrey Amendment (1952) +y +y +y

, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
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on
c. Controlled Substances Act (1970) +y +y +y


d. Kefauver Harris Drug Amendment (1962) +y +y +y +y




ANS: A +y


The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
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safety of all drugs before marketing. Later amendments and acts helped tighten FDA cont
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rol and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drug
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s that cannot be used safely without medical supervision and restricts their sale to prescrip
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tion by a licensed practitioner. The Controlled Substances Act addresses only controlled su
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bstances andtheir categorization. The Kefauver Harris Drug Amendment ensures drug effic
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acy and greaterdrug safety. Drug manufacturers are required to prove to the FDA the effe
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ctiveness of their products before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 +y +y +y +y +y +y


OBJ: 5 + y


NAT: NCLEX Client Needs Category: Physiological Integri +y +y +y +y +y +y


tyTOP: Nursing Process Step: Assessment
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CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B +y


Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lea
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d tosevere psychological and physical dependence. Schedule I drugs have high potential for
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abuseand no recognized medical use. Schedule III drugs have some potential for abuse.
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Use may lead to low to moderate physical dependence or high psychological dependence.
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Schedule IVdrugs have low potential for abuse. Use may lead to limited physical or psyc
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hological dependence. +y




DIF: Cognitive Level: Knowledge REF: p. 10 +y +y + y +y


OBJ: 2NAT: NCLEX Client Needs Category: Safe, Effective C
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are Environment
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TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
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8. Which action would the FDA take to expedite drug development and approval for an outbre
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akof smallpox?
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a. List smallpox as a health orphan disease.
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b. Omit the preclinical research phase. +y +y +y +y


c. Extend the clinical research phase. +y +y +y +y


d. Fast track the investigational drug.+y +y +y +y




ANS: D +y


Once the Investigational New Drug Application has been approved, the drug can receive
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highest priority within the agency, which is called fast tracking. A smallpox outbreak wou
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ld become a priority concern in the world. Orphan diseases are not researched in a priorit
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y manner. Preclinical research is not omitted. Extending any phase of the research would
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meana longer time to develop a vaccine. The FDA must ensure that all phases of the preclin
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ical andclinical research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge +y +y REF: +y+y+y p. 7 +y OBJ: 5 +y