Exam Practice Questions and Correct Answers
(Verified Answers) Plus Rationales 2026/2027 Q&A|
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1. Which anticoagulant is most appropriate for a complete blood count (CBC)?
A. EDTA
B. Heparin
C. Sodium citrate
D. Oxalate
Answer & Rationale: A. EDTA – Preserves cellular morphology and prevents clotting,
making it ideal for CBC analysis.
2. Which of the following is the normal reference range for adult hemoglobin?
A. 13–17 g/dL for males, 12–16 g/dL for females
B. 10–14 g/dL for males, 9–13 g/dL for females
C. 15–19 g/dL for males, 14–18 g/dL for females
D. 11–15 g/dL for males, 10–14 g/dL for females
Answer & Rationale: A. 13–17 g/dL (males), 12–16 g/dL (females) – Standard adult
hemoglobin reference range for healthy individuals.
3. Which test is used to monitor long-term glucose control in diabetic patients?
A. Hemoglobin A1c
B. Fasting blood glucose
C. Random plasma glucose
D. Oral glucose tolerance test
Answer & Rationale: A. Hemoglobin A1c – Reflects average blood glucose over 2–3
months.
4. What is the principle of the Wright-Giemsa stain used in hematology?
A. Differential staining of blood cell types
B. Detection of bacterial infections
C. Protein quantification
D. Lipid analysis
Answer & Rationale: A. Differential staining – Allows visualization of RBCs, WBCs, and
platelets for morphology evaluation.
5. Which of the following is the primary function of a centrifuge in a clinical laboratory?
A. Separate components of blood or other specimens
B. Measure pH
, C. Detect antibodies
D. Culture microorganisms
Answer & Rationale: A. Separation – Uses centrifugal force to separate plasma, serum, and
cellular elements for testing.
6. Which urine test is most appropriate for detecting early kidney disease?
A. Microalbuminuria
B. Urine glucose
C. Urine ketones
D. Urine bilirubin
Answer & Rationale: A. Microalbuminuria – Detects small amounts of protein in urine,
indicating early renal damage.
7. Which of the following is the best method for sterilizing heat-sensitive laboratory
equipment?
A. Ethylene oxide gas
B. Autoclaving
C. Boiling
D. UV light only
Answer & Rationale: A. Ethylene oxide – Chemical sterilization suitable for heat-sensitive
instruments.
8. Which white blood cell is primarily responsible for allergic reactions?
A. Eosinophils
B. Neutrophils
C. Monocytes
D. Lymphocytes
Answer & Rationale: A. Eosinophils – Play a key role in allergic responses and parasitic
infections.
9. Which of the following is the most common cause of hemolytic anemia?
A. Autoimmune destruction of RBCs
B. Iron deficiency
C. Vitamin B12 deficiency
D. Thalassemia minor
Answer & Rationale: A. Autoimmune – Autoantibodies target RBCs, leading to premature
destruction.
10. Which laboratory test measures the coagulation pathway integrity?
A. Prothrombin time (PT) and activated partial thromboplastin time (aPTT)
B. Complete blood count
, C. Blood glucose
D. Serum electrolytes
Answer & Rationale: A. PT and aPTT – Assess extrinsic and intrinsic coagulation
pathways, respectively.
11. Which blood collection tube contains sodium citrate?
A. Light blue top
B. Lavender top
C. Green top
D. Red top
Answer & Rationale: A. Light blue – Sodium citrate prevents coagulation and is used for
coagulation studies.
12. Which microorganism is detected using acid-fast staining?
A. Mycobacterium tuberculosis
B. Escherichia coli
C. Staphylococcus aureus
D. Candida albicans
Answer & Rationale: A. Mycobacterium tuberculosis – Acid-fast stain identifies
mycobacteria due to their waxy cell wall.
13. What is the normal platelet count range in adults?
A. 150,000–450,000/µL
B. 100,000–300,000/µL
C. 200,000–500,000/µL
D. 50,000–150,000/µL
Answer & Rationale: A. 150,000–450,000/µL – Standard reference range for healthy
adults.
14. Which enzyme is commonly measured to assess liver function?
A. Alanine aminotransferase (ALT)
B. Creatine kinase
C. Amylase
D. Lactate dehydrogenase
Answer & Rationale: A. ALT – Elevated levels indicate hepatocellular injury.
15. Which of the following blood components is most affected by hemolysis during
collection?
A. Potassium
B. Sodium