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PSL 310 EXAM 4 QUESTIONS WITH COMPLETE ANSWERS

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PSL 310 EXAM 4 QUESTIONS WITH COMPLETE ANSWERS

Institution
PSL 310
Course
PSL 310

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What effect does the binding of proton to hemoglobin have on its function?


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it decreases hemoglobin's affinity for oxygen




Based on a manual calculation of a hematocrit for someone that is dehydrated, would
the person appear to be anemic or polycythemic?


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polycythemic




What hormones stimulate erythropoiesis?

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-erythropoietin


-testosterone


-growth hormone

-thyroid hormone




What vessels does the right ventricle pump blood into?


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-into the pulmonary trunk, which leads to the pulmonary arteries




compare and contrast sickle-cell trait and sickle-cell disease


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-trait, you are a carrier for the disease and you are heterozygous for the
allele (HgbAS)

-disease, you are homozygous for the allele (HgbSS)

-disease life expectancy is 40-50 years

-only treatment is blood transfusion or bone marrow transplant




What is the major hormone that stimulates erythropoiesis?

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-erythropoietin (EPO)

-JG apparatus cells secrete this hormone in the kidney

-hormone is secreted under hypoxic conditions




How would baroreflex respond to acute bout of hypotension or hypertension?


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-Hypotension, there would be an increase sympathetic activity to the heart
and vasculature, and a reduction in parasympathetic activity to the heart


-hypertension, would decrease sympathetic activity to the heart and
vasculature and an increase in parasympathetic activity to the heart.




Where is the binding site for oxygen on hemoglobin?


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to the iron




What blood types can AB- receive?


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, A-, B-, AB-, O-




How are cardiac output and total peripheral resistance pharmacologically modulated
to lower mean arterial pressure?


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-CO is modulated by beta blockers to reduce the CO by weakening the
pump

-TPR is modulated by alpha blockers to reduce TPR by vasodilating blood
vessels




What are the 2 main components of heme?


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-porphyrin rings and ferrous iron




What are the different methods that individuals employ for blood doping?


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-testosterone and EPO are used for blood doping

-they can also take blood out their own body and then reinject it

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