SBB study guide Exam questions 2026
Exam Questions and verified Answers .
What enzyme may be useful in distinguishing anti-Ge2 from anti-Ge3? - CORRECT ANSWERS
Papain (Anti-Ge2 will not react)
The beta 1-3 linkage between galactose and N-actylglucosamine is found in: - CORRECT ANSWERS
Secretions
Which of the following represents the Type II chain? - CORRECT ANSWERS Beta 1-4
linkage between galactose and N acetyl glucosamine
Rank the order of decreasing H concentration on RBCs - CORRECT ANSWERS
0>A2>B>A2B>A1>A1B
All of the following are genotypes for the A1 phenotype except:
1. A1/A1
2. A1/A2
3. A2/B
4. A1/O - CORRECT ANSWERS A2/B
The ABO genes are located on which chromosome? - CORRECT ANSWERS 9
Which glycosyltransferase is needed before A and B antigens are formed? - CORRECT ANSWERS
L-fucosyltransferase
What is the typical reaction of the A3 subgroup? - CORRECT ANSWERS mixed field
reaction with Anti-A and Anti-A,B
What is the typical reaction of the Ael subgroup? - CORRECT ANSWERS Positive
reaction with anti-H
What clinical condition may yield positive reactions with Anti-A, negative with Anti-B, negative with
A1 and B cells. - CORRECT ANSWERS Hypogammaglobulinemia
What differentiates a Bombay anti-H from an anti-H cold agglutin? - CORRECT ANSWERS
Reactivity at body temperature
The is antigen is associated with linear carbohydrate chains? - CORRECT ANSWERS i
antigen
The following reactions are found on a 35 yr old male. Anti-A 4+, Anti-B 0, Anti-A,B-4+, A1 cells 3+,
B cells 4+, O cells 3+. How could these be explained? - CORRECT ANSWERS Anti-M in
plasma
Anti-IH would react best with which RBC? - CORRECT ANSWERS O
, The acquired B phenomenon is only found in which ABO group? - CORRECT ANSWERS
A
Which of the following is true about the A2 subgroup?
1. 1-8% of persons will product anti-A1
2. Anti-A1 does not react with A2 RBCs
3. Anti-A2 is formed
4. Two of the above - CORRECT ANSWERS Two of the above (1-8% of persons will
product anti-A1 and Anti-A1 does not react with A2 RBC )
Anti-Lu3 is associated with: - CORRECT ANSWERS Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what gene? - CORRECT ANSWERS In(Lu)
What substance could be used to rule out anti-E in the presence of anti-Lub? - CORRECT ANSWERS
DTT
Which pair of alleles is out of place?
1. Lu8/Lu14
2. Lu8/Lu10
3.Lu6/Lu9
4. Aua/Aub - CORRECT ANSWERS Lu8/Lu10
Persons who are group B are more common among which population? - CORRECT ANSWERS
Black/Asian
Red cells that lack glycophrin A also lack: - CORRECT ANSWERS Ena antigens
Anti-ENKT reacts with which RBCs? - CORRECT ANSWERS ENaFS
What is a lectin? - CORRECT ANSWERS Seed extracts that agglutinate human cells with
moderate specificity
All of the following are representative of Lewis antibodies, except?
1. They can be neutralized by Lewis substance
2. They occur frequently in pregnant women
3. They are destroyed by enzymes
4. They are enhanced by enzymes - CORRECT ANSWERS They are destroyed by
enzymes
Why can anti-H sometimes be fund in A2B persons? - CORRECT ANSWERS The specific
immunodominant sugar blocks the presence of H antigen
Why is determenantion of Rh status crucial for obstetric patients? - CORRECT ANSWERS
All Rh negative mothers are possible candidates for Rhogam
An adult who inherits Le,Se and H will type as: - CORRECT ANSWERS Le(a-b+)
Exam Questions and verified Answers .
What enzyme may be useful in distinguishing anti-Ge2 from anti-Ge3? - CORRECT ANSWERS
Papain (Anti-Ge2 will not react)
The beta 1-3 linkage between galactose and N-actylglucosamine is found in: - CORRECT ANSWERS
Secretions
Which of the following represents the Type II chain? - CORRECT ANSWERS Beta 1-4
linkage between galactose and N acetyl glucosamine
Rank the order of decreasing H concentration on RBCs - CORRECT ANSWERS
0>A2>B>A2B>A1>A1B
All of the following are genotypes for the A1 phenotype except:
1. A1/A1
2. A1/A2
3. A2/B
4. A1/O - CORRECT ANSWERS A2/B
The ABO genes are located on which chromosome? - CORRECT ANSWERS 9
Which glycosyltransferase is needed before A and B antigens are formed? - CORRECT ANSWERS
L-fucosyltransferase
What is the typical reaction of the A3 subgroup? - CORRECT ANSWERS mixed field
reaction with Anti-A and Anti-A,B
What is the typical reaction of the Ael subgroup? - CORRECT ANSWERS Positive
reaction with anti-H
What clinical condition may yield positive reactions with Anti-A, negative with Anti-B, negative with
A1 and B cells. - CORRECT ANSWERS Hypogammaglobulinemia
What differentiates a Bombay anti-H from an anti-H cold agglutin? - CORRECT ANSWERS
Reactivity at body temperature
The is antigen is associated with linear carbohydrate chains? - CORRECT ANSWERS i
antigen
The following reactions are found on a 35 yr old male. Anti-A 4+, Anti-B 0, Anti-A,B-4+, A1 cells 3+,
B cells 4+, O cells 3+. How could these be explained? - CORRECT ANSWERS Anti-M in
plasma
Anti-IH would react best with which RBC? - CORRECT ANSWERS O
, The acquired B phenomenon is only found in which ABO group? - CORRECT ANSWERS
A
Which of the following is true about the A2 subgroup?
1. 1-8% of persons will product anti-A1
2. Anti-A1 does not react with A2 RBCs
3. Anti-A2 is formed
4. Two of the above - CORRECT ANSWERS Two of the above (1-8% of persons will
product anti-A1 and Anti-A1 does not react with A2 RBC )
Anti-Lu3 is associated with: - CORRECT ANSWERS Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what gene? - CORRECT ANSWERS In(Lu)
What substance could be used to rule out anti-E in the presence of anti-Lub? - CORRECT ANSWERS
DTT
Which pair of alleles is out of place?
1. Lu8/Lu14
2. Lu8/Lu10
3.Lu6/Lu9
4. Aua/Aub - CORRECT ANSWERS Lu8/Lu10
Persons who are group B are more common among which population? - CORRECT ANSWERS
Black/Asian
Red cells that lack glycophrin A also lack: - CORRECT ANSWERS Ena antigens
Anti-ENKT reacts with which RBCs? - CORRECT ANSWERS ENaFS
What is a lectin? - CORRECT ANSWERS Seed extracts that agglutinate human cells with
moderate specificity
All of the following are representative of Lewis antibodies, except?
1. They can be neutralized by Lewis substance
2. They occur frequently in pregnant women
3. They are destroyed by enzymes
4. They are enhanced by enzymes - CORRECT ANSWERS They are destroyed by
enzymes
Why can anti-H sometimes be fund in A2B persons? - CORRECT ANSWERS The specific
immunodominant sugar blocks the presence of H antigen
Why is determenantion of Rh status crucial for obstetric patients? - CORRECT ANSWERS
All Rh negative mothers are possible candidates for Rhogam
An adult who inherits Le,Se and H will type as: - CORRECT ANSWERS Le(a-b+)
