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Evolve NCLEX Prep Pharmacology Q&A Updated 2025–2026 Complete Exam Questions and Answers Study Guide for NCLEX Pharmacology Success

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This Evolve NCLEX Prep Pharmacology Q&A is a comprehensive exam preparation resource designed for nursing students preparing for NCLEX success in 2025–2026. It provides a structured set of practice questions and answers focused specifically on pharmacology concepts tested in licensure examinations. The content covers essential topics such as drug classifications, pharmacokinetics, pharmacodynamics, medication safety, dosage calculations, adverse drug reactions, contraindications, and patient education. It also emphasizes clinical judgment, prioritization, safety principles, and evidence-based medication administration across major body systems and disease conditions. This resource is ideal for revision, quizzes, mock exams, and final NCLEX preparation, helping students strengthen pharmacological reasoning, test-taking strategies, and clinical decision-making skills. It supports mastery of core medication knowledge required for safe and effective nursing practice and successful performance in NCLEX examinations.

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Institution
Nursing Pharmacology
Course
Nursing pharmacology

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NCLEX-RN
Examination, 5th Edition
Pharmacology Test Bank

,NCLEX-RN Examination, 5th Edition Pharmacology Test Bank




Pharmacology
MULTIPLE CHOICE

1. The nurse is caring for a client in labor. The nurse reviews the physician’s prescriptions and notes that T T T T T T T T T T T T T T



the client has a prescription for butorphanol tartrate (Stadol). The nurse understands that this medication
T T T T T T T T T T T T T T T



is prescribed for:
T T




1. Pain relief T




2. Increasing uterine contractions T T




3. Decreasing uterine contractions T T




4. Promoting fetal lung maturity T T T




ANS: 1 T




Rationale: The client in labor may be given parenteral analgesia during the first stage of labor, up to 2 to 3
T T T T T T T T T T T T T T T T T T T T T



hours before the anticipated delivery. Butorphanol tartrate is a medication that may be prescribed for
T T T T T T T T T T T T T T T



pain relief. “Increasing uterine contractions,” “decreasing uterine contractions,” and “promoting fetal
T T T T T T T T T T T



lung maturity” are not actions of this medication.
T T T T T T T




Test-Taking Strategy: Knowledge of the action of butorphanol tartrate is required to answer this
T T T T T T T T T T T T T T



question. Remember that this medication is used for pain relief. Review the action of this medication if
T T T T T T T T T T T T T T T T T



you had difficulty with this question and are unfamiliar with this medication.
T T T T T T T T T T T




PTS: 1
DIF: Level of Cognitive Ability: UnderstandingT T T T



REF: Lehne, R. (2010). Pharmacology for nursing care (7th ed.). St. Louis: Saunders.
T T T T T T T T T T T T



OBJ: Client Needs: Physiological Integrity T T T



TOP: Content Area: Pharmacology T T



MSC: Integrated Process: Nursing Process—Planning
T T T T




2. The postpartum nurse is caring for a client with an epidural catheter in place for opioid analgesic
T T T T T T T T T T T T T T T T T



administration following cesarean birth. If the client develops respiratory depression and requires
T T T T T T T T T T T T



naloxone (Narcan) as an antidote, the client may complain of which of the following?
T T T T T T T T T T T T T




1. Increase in her pain level T T T T




2. Decrease in her pain level T T T T

, 3. Increase in the amount of itching from the opioid used in the epidural
T T T T T T T T T T T T




ANS: 1 T




Rationale: Remember that opioids are used for epidural analgesia. Naloxone is an opioid antagonist,
T T T T T T T T T T T T T T



which reverses the effects of opioids. If it is given, the client may complain of an increase in her pain
T T T T T T T T T T T T T T T T T T T T



level. Therefore “decrease in her pain level,” “increase in the amount of itching from the opioid used in
T T T T T T T T T T T T T T T T T T



the epidural,” and “decrease in the amount of itching from the opioid used in the epidural” are incorrect.
T T T T T T T T T T T T T T T T T




Test-Taking Strategy: To answer this question accurately, you must know that opioid analgesics are the
T T T T T T T T T T T T T T T



medications used with epidural analgesia to relieve pain. Therefore if naloxone is administered as an
T T T T T T T T T T T T T T T



antidote for an opioid analgesic, the client’s pain will increase. Review the effects of naloxone if this
T T T T T T T T T T T T T T T T T



question was difficult. T T




PTS: 1
DIF: Level of Cognitive Ability: Understanding T T T T



REF: Lehne, R. (2010). Pharmacology for nursing care (7th ed.). St. Louis: Saunders.
T T T T T T T T T T T T



OBJ: Client Needs: Physiological Integrity T T T



TOP: Content Area: Pharmacology T T



MSC: Integrated Process: Nursing Process—Assessment
T T T T




3. A client experiencing preterm labor at the twenty-ninth week of gestation has been admitted to the
T T T T T T T T T T T T T T T T



hospital. The client has a prescription to receive betamethasone (Celestone). The nurse understands that
T T T T T T T T T T T T T T



the medication will do which of the following?
T T T T T T T




1. Prevent spontaneous delivery. T T




2. Stop the uterine contractions.
T T T




3. Promote maturation of the fetal lungs. T T T T T




4. Accelerate the growth rate of the fetus. T T T T T T




ANS: 3 T




Rationale: Betamethasone (Celestone) is classified as an anti-inflammatory and corticosteroid. It
T T T T T T T T T T T



increases the surfactant level and lung maturity in the fetus, which reduces the incidence of respiratory
T T T T T T T T T T T T T T T T



distress syndrome. Delivery must be delayed for at least 48 hours after administration of betamethasone to
T T T T T T T T T T T T T T T T



allow time for the lungs of the fetus to mature.
T T T T T T T T T




Test-Taking Strategy: Options that are comparable or alike are not likely to be correct. With this in
T T T T T T T T T T T T T T T T T



mind, eliminate “prevent spontaneous delivery” and “stop the uterine contractions.” Note the strategic
T T T T T T T T T T T T T



words “twenty-ninth week of gestation.” Specific knowledge about the medication and knowledge of the
T T T T T T T T T T T T T T



problems encountered by premature infants will assist in answering this question. Review the action of
T T T T T T T T T T T T T T T



this medication if this question was difficult.
T T T T T T




PTS: 1
DIF: Level of Cognitive Ability: Understanding T T T T



REF: McKinney, E., James, S., Murray, S., & Ashwill, J. (2009). Maternal-child nursing (3rd ed.). St. T T T T T T T T T T T T T T T



Louis: Saunders. OBJ: Client Needs: Physiological Integrity
T T T T

, TOP: Content Area: Pharmacology T T



MSC: Integrated Process: Nursing Process—Planning
T T T T




4. A client with preeclampsia is receiving magnesium sulfate. The nurse assesses the client closely for
T T T T T T T T T T T T T T T



which sign of magnesium toxicity?
T T T T




1. Proteinuria
2. Hyperactive deep tendon reflexes T T T




3. Respiratory rate of 10 breaths/min T T T T




4. Serum magnesium level of 5 mEq/L
T T T T T




ANS: 3 T




Rationale: Magnesium toxicity is a risk associated with magnesium sulfate therapy. Signs of magnesium
T T T T T T T T T T T T T T



toxicity relate to central nervous system (CNS) depression and include respiratory depression, loss of
T T T T T T T T T T T T T T



deep tendon reflexes, and sudden drop in fetal heart rate and/or maternal heart rate and blood pressure.
T T T T T T T T T T T T T T T T



Magnesium is excreted through the kidneys. If renal impairment is present, magnesium toxicity can
T T T T T T T T T T T T T T



develop very quickly. Therapeutic serum levels of magnesium are 4 to 7 mEq/L.
T T T T T T T T T T T T




Test-Taking Strategy: To answer this question accurately, you must recall that magnesium sulfate is a
T T T T T T T T T T T T T T T



CNS depressant. Begin to answer this question by eliminating “proteinuria” and “hyperactive deep
T T T T T T T T T T T T T



tendon reflexes,” which are signs of preeclampsia. Select between the last two options using medication
T T T T T T T T T T T T T T T



knowledge and recalling that the therapeutic serum levels of magnesium are 4 to 7 mEq/L. Review this
T T T T T T T T T T T T T T T T T



medication and the normal magnesium level if this question was difficult.
T T T T T T T T T T




PTS: 1
DIF: Level of Cognitive Ability: Analyzing T T T T



REF: Lowdermilk, D., Perry, S., & Cashion, K. (2010). Maternity nursing (8th ed.). St. Louis: Mosby.
T T T T T T T T T T T T T T



OBJ: Client Needs: Physiological Integrity T T T T



TOP: Content Area: Pharmacology T T



MSC: Integrated Process: Nursing Process—Assessment
T T T T




5. A pregnant client who has human immunodeficiency virus (HIV) infection is being seen in the antenatal
T T T T T T T T T T T T T T T T



clinic. The nurse recalls that zidovudine (AZT) therapy will be initiated when the fetus has reached how
T T T T T T T T T T T T T T T T T



many weeks of gestation?
T T T




1. 4
2. 14
3. 24
4. 34

ANS: 2 T




Rationale: The pregnant women with HIV infection will be prescribed oral AZT in the fourteenth week of
T T T T T T T T T T T T T T T T T



gestation. Before this time, the fetus is at risk because of the teratogenic effects of the medication. In
T T T T T T T T T T T T T T T T T

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Institution
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Course
Nursing pharmacology

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