Nightingale College Pathophysiology Midterm
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Terms in this set (76)
Pathophysiology The study of the underlying changes in body
physiology (molecular, cellular, and organ systems)
that result from disease or injury.
Pathology The investigation of structural alterations in cells,
tissues, and organs, which can help identify the
cause of a particular disease.
Diagnosis The naming or identification of a disease - is made
from an evaluation of the evidence accumulated
from the presenting signs and symptoms, health
and medical history, physical examination,
laboratory tests, and imaging.
Etiology The study of the CAUSE of disease
Epidemiology The study of tracking patterns or disease
occurrence and transmission among populations
and by geographic areas
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Nucleus Controls and regulates the activities of the cell
(e.g., growth and metabolism) and carries the
genes, structures that contain the hereditary
information
Cytoplasm An aqueous solution. The medium for chemical
reaction. It provides a platform upon which other
organelles can operate within the cell. All of the
functions for cell expansion, growth and replication
are carried out in the cytoplasm of a cell.
Ribosomes Provide sites for cellular protein synthesis.
Endoplasmic Reticulum Specializes in synthesis, folding, and transport of
protein and lipid components of most organelles. A
new role is sensing cellular stress.
Golgi apparatus Responsible for processing and packaging proteins
onto secretory vesicles that break away from the
complex and migrate to various intracellular and
extracellular destinations, including plasma
membrane.
Lysosomes Contain enzymes for digesting most cellular
substances to their basic form, such as amino acids,
fatty acids, and carbohydrates (sugars).
Peroxisomes Contain oxidase enzymes that detoxify alcohol,
hydrogen peroxide, and other harmful chemicals
Mitochondria Powerhouse of the cell, organelle that is the site of
ATP (energy) production
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Cytoskeleton Network of protein filaments within some cells that
helps the cell maintain its shape and is involved in
many forms of cell movement
Plasma Membrane The membrane at the boundary of every cell that
acts as a selective barrier, thereby regulating the
cell's chemical composition.
Signaling processes 1. They display plasma membrane-bound signaling
molecules (receptors) that affect the cell itself and
other cells in direct physical contact
2. They affect receptor proteins inside the target
cell and the signal molecule has to enter the cell to
bind to them
3. They form protein channels (gap junctions) that
directly coordinate the activities of adjacent cells
Adaptive cellular mechanism - Decrease in cell size
Atrophy:
Adaptive cellular mechanism - Increase in cell size
Hypertrophy:
Adaptive cellular mechanism - Increase in cell number
Hyperplasia:
Adaptive cellular mechanism - Reversible replacement of one mature cell type by
Metaplasia: another, less mature cell type or a change in cell
phenotype
Adaptive cellular mechanism - Deranged cellular growth, is not considered a true
Dysplasia: cellular adaptation but rather atypical hyperplasia
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